CRISPR Genome Editing & Therapy

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

June 26, 2020

CRISPR-Cas13a Inhibits HIV-1 Infection

Molecular Therapy. Nucleic Acids
Lijuan YinFei Guo
May 21, 2020

Applications of CRISPR-Cas systems in Lactic Acid Bacteria

FEMS Microbiology Reviews
Avery Roberts, Rodolphe Barrangou
May 23, 2020
Review

Precision Therapy for Inherited Retinal Disease: At the Forefront of Genomic Medicine

Clinics in Laboratory Medicine
Nicole Koulisis, Aaron Nagiel
June 11, 2020

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

ELife
Joshua C CofskyJennifer A Doudna
May 28, 2020
Open Access

PaCRISPR: a server for predicting and visualizing anti-CRISPR proteins

Nucleic Acids Research
Jiawei WangTrevor Lithgow
June 23, 2020

CRISPR Genome Editing Technology and its Application in Genetic Diseases: A Review

Current Pharmaceutical Biotechnology
Sepideh KhatibiSeyed Hamid Aghaee Bakhtiari
June 2, 2020
Review

Correction of muscular dystrophies by CRISPR gene editing

The Journal of Clinical Investigation
Francesco ChemelloEric N Olson
May 18, 2020

Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

Cell Death and Differentiation
Soumyadip DasSuresh Ramakrishna
June 26, 2020

Photoactivatable RNA N6 -Methyladenosine Editing with CRISPR-Cas13

Small
Jie ZhaoXinlong Ma
June 20, 2020
Open Access

Orthogonal tuning of gene expression noise using CRISPR-Cas

Nucleic Acids Research
Fan WuCheemeng Tan
June 26, 2020

Super-enhancer acquisition drives oncogene expression in triple negative breast cancer

PloS One
Ryan RaisnerKaren E Gascoigne
June 9, 2020
Open Access

The Improvement of CRISPR-Cas9 System With Ubiquitin-Associated Domain Fusion for Efficient Plant Genome Editing

Frontiers in Plant Science
Xuelian ZhengYong Zhang
July 7, 2020
Preprint

A High-efficacy CRISPRi System for Gene Function Discovery in Zymomonas mobilis

BioRxiv : the Preprint Server for Biology
Jason M PetersC. Siletti
May 19, 2020

CRISPR-Directed Therapeutic Correction at the NCF1 Locus Is Challenged by Frequent Incidence of Chromosomal Deletions

Molecular Therapy. Methods & Clinical Development
Dominik WronaJanine Reichenbach
July 3, 2020
Open Access

Expression of ncRNAs on the DLK1-DIO3 Locus Is Associated With Basal and Mesenchymal Phenotype in Breast Epithelial Progenitor Cells

Frontiers in Cell and Developmental Biology
Zuzana BudkovaBylgja Hilmarsdottir
May 21, 2020
Correction
Open Access

Author Correction: Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

Nature Biotechnology
Michelle F RichterDavid R Liu
June 9, 2020

Gene editing technology for improving life quality: A dream coming true?

Clinical Genetics
Roya RamezankhaniCatherine M Verfaillie
June 3, 2020
Open Access

Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death

Nature Communications
Eduardo BalsaPere Puigserver
May 11, 2020
Review

Advances in genome editing for genetic hearing loss

Advanced Drug Delivery Reviews
Ning DingXue Gao

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