CRISPR Genome Editing & Therapy

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

October 17, 2021

CellFIE: CRISPR- and cell fusion-based two-hybrid interaction mapping of endogenous proteins.

Journal of Molecular Biology
Christopher SeckerErich E Wanker
October 17, 2021

CRISPR/Cas9 in cancer therapy: A review with a special focus on tumor angiogenesis.

International Journal of Biological Macromolecules
Krishnasamy Naidu Gopal HariprabuSelvaraj Vimalraj
October 17, 2021

Loss of KDM1A in GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome: a multicentre, retrospective, cohort study.

The Lancet. Diabetes & Endocrinology
Fanny ChasseloupPeter Kamenický
October 16, 2021

Human kidney organoids reveal the role of glutathione in Fabry disease.

Experimental & Molecular Medicine
Jin Won KimYong Kyun Kim
October 16, 2021

Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis.

Journal of Experimental & Clinical Cancer Research : CR
Oxana SchmidtGünther H S Richter
October 16, 2021

Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model.

Stem Cell Reports
Kathleen R ChircoDeepak A Lamba
October 15, 2021

Prenatal Gene Therapy for Metabolic Disorders.

Clinical Obstetrics and Gynecology
Barbara Coons, William H Peranteau
October 15, 2021

Precise genomic deletions using paired prime editing.

Nature Biotechnology
Junhong ChoiJay Shendure
October 15, 2021

Inherent hepatocytic heterogeneity determines expression and retention of edited F9 alleles post-AAV/CRISPR infusion.

Proceedings of the National Academy of Sciences of the United States of America
Qiang WangSai-Juan Chen
October 15, 2021
Open Access

Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.

Molecular Cancer
Yang GuZusen Fan
October 14, 2021
Open Access

A Novel Mice Model of Catecholaminergic Polymorphic Ventricular Tachycardia Generated by CRISPR/Cas9

BioRxiv : the Preprint Server for Biology
c. houXiao tingting
October 13, 2021

DNA barcode to trace the development and differentiation of cord blood stem cells (Review).

Molecular Medicine Reports
Mo-Yu WangHong-Wu Xin
October 13, 2021

Evolution of RNA viruses from SARS to SARS-CoV-2 and diagnostic techniques for COVID-19: a review.

Beni-Suef University Journal of Basic and Applied Sciences
Johra KhanJames H Zothantluanga
October 13, 2021

Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells.

Journal of Experimental & Clinical Cancer Research : CR
Tamara RothenburgerJindrich Cinatl

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