CRISPR Genome Editing & Therapy

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

June 26, 2020

CRISPR-Cas13a Inhibits HIV-1 Infection

Molecular Therapy. Nucleic Acids
Lijuan YinFei Guo
May 21, 2020

Applications of CRISPR-Cas systems in Lactic Acid Bacteria

FEMS Microbiology Reviews
Avery Roberts, Rodolphe Barrangou
May 23, 2020

Precision Therapy for Inherited Retinal Disease: At the Forefront of Genomic Medicine

Clinics in Laboratory Medicine
Nicole Koulisis, Aaron Nagiel
June 11, 2020

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

Joshua C CofskyJennifer A Doudna
May 28, 2020
Open Access

PaCRISPR: a server for predicting and visualizing anti-CRISPR proteins

Nucleic Acids Research
Jiawei WangTrevor Lithgow
June 23, 2020

CRISPR Genome Editing Technology and its Application in Genetic Diseases: A Review

Current Pharmaceutical Biotechnology
Sepideh KhatibiSeyed Hamid Aghaee Bakhtiari
June 2, 2020

Correction of muscular dystrophies by CRISPR gene editing

The Journal of Clinical Investigation
Francesco ChemelloEric N Olson
May 18, 2020

Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

Cell Death and Differentiation
Soumyadip DasSuresh Ramakrishna
June 26, 2020

Photoactivatable RNA N6 -Methyladenosine Editing with CRISPR-Cas13

Jie ZhaoXinlong Ma
June 20, 2020
Open Access

Orthogonal tuning of gene expression noise using CRISPR-Cas

Nucleic Acids Research
Fan WuCheemeng Tan
June 26, 2020

Super-enhancer acquisition drives oncogene expression in triple negative breast cancer

PloS One
Ryan RaisnerKaren E Gascoigne
June 9, 2020
Open Access

The Improvement of CRISPR-Cas9 System With Ubiquitin-Associated Domain Fusion for Efficient Plant Genome Editing

Frontiers in Plant Science
Xuelian ZhengYong Zhang
July 7, 2020

A High-efficacy CRISPRi System for Gene Function Discovery in Zymomonas mobilis

BioRxiv : the Preprint Server for Biology
Jason M PetersC. Siletti
May 19, 2020

CRISPR-Directed Therapeutic Correction at the NCF1 Locus Is Challenged by Frequent Incidence of Chromosomal Deletions

Molecular Therapy. Methods & Clinical Development
Dominik WronaJanine Reichenbach
July 3, 2020
Open Access

Expression of ncRNAs on the DLK1-DIO3 Locus Is Associated With Basal and Mesenchymal Phenotype in Breast Epithelial Progenitor Cells

Frontiers in Cell and Developmental Biology
Zuzana BudkovaBylgja Hilmarsdottir
May 21, 2020
Open Access

Author Correction: Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

Nature Biotechnology
Michelle F RichterDavid R Liu
June 9, 2020

Gene editing technology for improving life quality: A dream coming true?

Clinical Genetics
Roya RamezankhaniCatherine M Verfaillie
June 3, 2020
Open Access

Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death

Nature Communications
Eduardo BalsaPere Puigserver
May 11, 2020

Advances in genome editing for genetic hearing loss

Advanced Drug Delivery Reviews
Ning DingXue Gao

Sign up to follow this feed and discover related papers.

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

Adult Kidney Organoids at Single Cell Resolution

Single-cell RNA sequencing of the adult human kidney transcriptome can provide molecular information about cell-specific responses to environmental variables and disease states. This information can provide a dataset to benchmark human kidney organoids. Discover the latest research on adult kidney organoids at single cell resolution here.

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antisense Oligonucleotide - Therapies For ALS

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Artificial Cell Models

This feed focuses on biomimetrics, synthetic biology and bio- and tissue-engineering approaches used for modeling human diseases.

Artificial Chromosomes

Artificial chromosomes are genetically engineered chromosomes derived from the DNA of a species. Discover the latest research on artificial chromosomes here.

© 2020 Meta ULC. All rights reserved