CRISPR in Cancer

CRISPR-Cas system enables the editing of genes to create or correct mutations. Given that genome instability and mutation is one of the hallmarks of cancer, the CRISPR-Cas system is being explored to genetically alter and eliminate cancer cells. Here is the latest research.

June 24, 2020

The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment

Acta Neuropathologica
Yan Ting LiuZhe Bao Wu
June 21, 2020
Review

Long non-coding RNA in cervical cancer: From biology to therapeutic opportunity

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Jiaxing HeTianmin Xu
May 27, 2020
Review

Argonaute proteins: Structural features, functions and emerging roles

Journal of Advanced Research
Jin'en WuYadong Zheng
July 1, 2020
Review
Open Access

Innovative Precision Gene-Editing Tools in Personalized Cancer Medicine

Advanced Science
Xiaofeng DaiKostya Ken Ostrikov
May 20, 2020

3D Spheroids Propel Tumor Characterization

Trends in Cancer
Shengli LiLeng Han
June 13, 2020
Open Access

The Role of BAFF-R Signaling in the Growth of Primary Central Nervous System Lymphoma

Frontiers in Oncology
Xiaolan ZhouLouisa von Baumgarten
June 9, 2020

Haploinsufficiency of the Primary Familial Brain Calcification Gene SLC20A2 Mediated by Disruption of a Regulatory Element

Movement Disorders : Official Journal of the Movement Disorder Society
Kévin CassinariGaël Nicolas
July 3, 2020

Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer

Clinical & Experimental Metastasis
Yahui HuangQiongqiong He
May 20, 2020

Targeting RLIP with CRISPR/Cas9 controls tumor growth

Carcinogenesis
Jyotsana SinghalSharad S Singhal
July 3, 2020
Open Access

Expression of ncRNAs on the DLK1-DIO3 Locus Is Associated With Basal and Mesenchymal Phenotype in Breast Epithelial Progenitor Cells

Frontiers in Cell and Developmental Biology
Zuzana BudkovaBylgja Hilmarsdottir
June 9, 2020
Review
Open Access

Molecular mechanisms, off-target activities, and clinical potentials of genome editing systems

Clinical and Translational Medicine
Nannan ZhengXiangdong Wang

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