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CRISPR in Cancer

CRISPR in Cancer diagram by Meletios Verras, Shutterstock
Meletios Verras, Shutterstock

CRISPR-Cas system enables the editing of genes to create or correct mutations. Given that genome instability and mutation is one of the hallmarks of cancer, the CRISPR-Cas system is being explored to genetically alter and eliminate cancer cells. Here is the latest research.

Top 20 most recent papers
Science

CRISPR-engineered T cells in patients with refractory cancer

ScienceFebruary 8, 2020
Edward A StadtmauerCarl H June
786
72
5
1
Nature Cell Biology

Programmable base editing of mutated TERT promoter inhibits brain tumour growth

Nature Cell BiologyFebruary 19, 2020
Xinjian LiZhimin Lu
10
1
Clinical Genetics

Applications of CRISPR-Cas9 in Gynecological Cancer Research

Clinical GeneticsFebruary 11, 2020
Wei ZhangHongbo Wang
2
Cold Spring Harbor Perspectives in Medicine

Mouse Models of Myeloid Malignancies

Cold Spring Harbor Perspectives in MedicineFebruary 20, 2020
Faisal Basheer, George Vassiliou
1
Frontiers in Microbiology

Multiplexed Knockouts in the Model Diatom Phaeodactylum by Episomal Delivery of a Selectable Cas9

Frontiers in MicrobiologyFebruary 13, 2020
Mark Andrew MoosburnerAndrew E Allen
5
4
Journal of Cancer Research and Clinical Oncology

The PI3K pathway impacts stem gene expression in a set of glioblastoma cell lines

Journal of Cancer Research and Clinical OncologyFebruary 8, 2020
Eduardo MartinezMegan Keniry
Briefings in Functional Genomics

CRISPR/Cas9 for cancer treatment: technology, clinical applications and challenges

Briefings in Functional GenomicsFebruary 14, 2020
Xing ChenXianfa Du
1

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