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CRISPR in Cancer

CRISPR in Cancer diagram by Meletios Verras, Shutterstock
Meletios Verras, Shutterstock

CRISPR-Cas system enables the editing of genes to create or correct mutations. Given that genome instability and mutation is one of the hallmarks of cancer, the CRISPR-Cas system is being explored to genetically alter and eliminate cancer cells. Here is the latest research.

Top 20 most recent papers

CRISPR-engineered T cells in patients with refractory cancer

ScienceFebruary 8, 2020
Edward A StadtmauerCarl H June
Nature Cell Biology

Programmable base editing of mutated TERT promoter inhibits brain tumour growth

Nature Cell BiologyFebruary 19, 2020
Xinjian LiZhimin Lu
Clinical Genetics

Applications of CRISPR-Cas9 in Gynecological Cancer Research

Clinical GeneticsFebruary 11, 2020
Wei ZhangHongbo Wang
Cold Spring Harbor Perspectives in Medicine

Mouse Models of Myeloid Malignancies

Cold Spring Harbor Perspectives in MedicineFebruary 20, 2020
Faisal Basheer, George Vassiliou
Frontiers in Microbiology

Multiplexed Knockouts in the Model Diatom Phaeodactylum by Episomal Delivery of a Selectable Cas9

Frontiers in MicrobiologyFebruary 13, 2020
Mark Andrew MoosburnerAndrew E Allen
Journal of Cancer Research and Clinical Oncology

The PI3K pathway impacts stem gene expression in a set of glioblastoma cell lines

Journal of Cancer Research and Clinical OncologyFebruary 8, 2020
Eduardo MartinezMegan Keniry
Briefings in Functional Genomics

CRISPR/Cas9 for cancer treatment: technology, clinical applications and challenges

Briefings in Functional GenomicsFebruary 14, 2020
Xing ChenXianfa Du

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