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CRISPR in Cancer

CRISPR in Cancer diagram by Meletios Verras, Shutterstock
Meletios Verras, Shutterstock

CRISPR-Cas system enables the editing of genes to create or correct mutations. Given that genome instability and mutation is one of the hallmarks of cancer, the CRISPR-Cas system is being explored to genetically alter and eliminate cancer cells. Here is the latest research.

Top 20 most recent papers
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchApril 5, 2020
James R WhittleGeoffrey J Lindeman
Anticancer Research

PTEN Is Involved in Sunitinib and Sorafenib Resistance in Renal Cell Carcinoma

Anticancer ResearchApril 3, 2020
Yohei SekinoAkio Matsubara

Integrated Molecular Characterisation of the MAPK Pathways in Human Cancers

bioRxivMarch 16, 2020
Musalula SinkalaDarren Patrick Martin
Cell Communication and Signaling : CCS

Angiopoietin-2 induces angiogenesis via exosomes in human hepatocellular carcinoma

Cell Communication and Signaling : CCSMarch 19, 2020
Ji-Yan XieJun Min
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

MAPK pathway alterations correlate with poor survival and drive resistance to therapy in patients with lung cancers driven by ROS1 fusions

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchMarch 4, 2020
Hiroki SatoRomel Somwar
Frontiers in Chemistry

The CRISP(Y) Future of Pediatric Soft Tissue Sarcomas

Frontiers in ChemistryApril 2, 2020
Silvia Pomella, Rossella Rota
Plant Biotechnology Journal

Elevating seed oil content in a polypoid crop by induced mutations in SEED FATTY ACID REDUCER genes

Plant Biotechnology JournalMarch 28, 2020
Nirosha L KarunarathnaChristian Jung

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