CRISPR in Malaria

CRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.

February 11, 2020

Digital droplet PCR and IDAA for the detection of CRISPR indel edits in the malaria species Anopheles stephensi

Rebeca Carballar-LejarazúAnthony A James
December 7, 2019
Open Access

Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii

Proceedings of the National Academy of Sciences of the United States of America
Alex RosenbergL David Sibley
February 25, 2020
Open Access

Anopheles stephensi as an emerging malaria vector in the Horn of Africa with high susceptibility to Ethiopian Plasmodium vivax and Plasmodium falciparum isolates

BioRxiv : the Preprint Server for Biology
Temesgen Ashine AmenuFitsum G Tadesse
September 23, 2019
Open Access

An assessment of adult mosquito collection techniques for studying species abundance and diversity in Maferinyah, Guinea

BioRxiv : the Preprint Server for Biology
Cintia Cansado UtrillaThomas Walker
November 18, 2019
Open Access

Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes

BioRxiv : the Preprint Server for Biology
Aditi KulkarniJiannong Xu
October 14, 2019

Long term prevention and vector control of arboviral diseases: What does the future hold?

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Bernardo Pereira CabralFabio Batista Mota
April 26, 2020

Gastric injury secondary to button battery ingestions: a retrospective multicenter review

Gastrointestinal Endoscopy
Racha T KhalafThomas Walker
December 20, 2019
Open Access

Experimental population modification of the malaria vector mosquito, Anopheles stephensi

PLoS Genetics
Thai Binh PhamAnthony A James
October 30, 2019
Open Access

Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection

The Journal of Experimental Medicine
Jing YangErol Fikrig
March 11, 2020
Open Access

Toward the Definition of Efficacy and Safety Criteria for Advancing Gene Drive-Modified Mosquitoes to Field Testing

Vector Borne and Zoonotic Diseases
Stephanie L JamesTony Nolan
May 21, 2020
Open Access

Inhibition of Asaia in Adult Mosquitoes Causes Male-Specific Mortality and Diverse Transcriptome Changes

Maria Vittoria ManciniGuido Favia
November 19, 2019
Open Access

Winning the Tug-of-War Between Effector Gene Design and Pathogen Evolution in Vector Population Replacement Strategies

Frontiers in Genetics
John M MarshallOmar S Akbari
March 27, 2020
Open Access

An assessment of adult mosquito collection techniques for studying species abundance and diversity in Maferinyah, Guinea

Parasites & Vectors
Cintia Cansado-UtrillaThomas Walker
December 19, 2019
Comment / Editorial
Open Access

Gene drive: progress and prospects

Proceedings. Biological Sciences
N WedellA K Lindholm
January 30, 2020

Assessing connectivity despite high diversity in island populations of a malaria mosquito

Evolutionary Applications
Christina M BergeyNora J Besansky

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