Feed Preview

Crispr In Malaria

Crispr In Malaria diagram by undefined

CRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.

Top 20 most recent papers
Science Translational Medicine

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum

Science Translational MedicineSeptember 18, 2019
Joost SchalkwijkKoen J Dechering
Nature Biotechnology

In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

Nature BiotechnologySeptember 25, 2019
Lupeng YeSidi Chen

High density Novel Wolbachia strains in Anopheles species from Guinea

bioRxivSeptember 24, 2019
Claire L. JeffriesThomas Walker

Evolution of resistance in vitro reveals a novel mechanism of artemisinin activity in Toxoplasma gondii.

bioRxivAugust 24, 2019
Alex RozenbergL. David David Sibley
Scientific Reports

High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation

Scientific ReportsOctober 16, 2019
Chrysanthi TaxiarchiRoberto Galizi
Scientific Reports

Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum

Scientific ReportsNovember 13, 2019
Hai T N BuiTill S Voss

EXP1 is required for organization of the intraerythrocytic malaria parasite vacuole

bioRxivAugust 31, 2019
Timothy NesselJosh R. Beck
The Journal of Experimental Medicine

Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection

The Journal of Experimental MedicineOctober 28, 2019
Jing YangErol Fikrig

Cas9-mediated gene-editing in the malaria mosquito Anopheles stephensi by ReMOT Control

bioRxivSeptember 19, 2019
Vanessa M. MaciasJason L. Rasgon

A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters

bioRxivNovember 8, 2019
Barbara FasuloNikolai Windbichler

An assessment of adult mosquito collection techniques for studying species abundance and diversity in Maferinyah, Guinea

bioRxivSeptember 23, 2019
Cintia Cansado UtrillaThomas Walker

A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle

MBioSeptember 17, 2019
Marta TibúrcioMoritz Treeck
BMC Medical Ethics

Informed consent and community engagement in open field research: lessons for gene drive science

BMC Medical EthicsJuly 27, 2019
Jerome Amir Singh

Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti.

bioRxivMay 24, 2019
Ming D LiOmar S. Akbari
Scientific Reports

Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy

Scientific ReportsAugust 19, 2019
Ratna VeeramachaneniNalin S Thakker
Malaria Journal

Characterizing the molecular and metabolic mechanisms of insecticide resistance in Anopheles gambiae in Faranah, Guinea

Malaria JournalJuly 17, 2019
Caleb SticaLouisa Alexandra Messenger
The CRISPR Journal

Redkmer: An Assembly-Free Pipeline for the Identification of Abundant and Specific X-Chromosome Target Sequences for X-Shredding by CRISPR Endonucleases

The CRISPR JournalFebruary 1, 2018
Philippos Aris A. Papathanos, Nikolai Windbichler
Scientific Reports

Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis

Scientific ReportsMarch 26, 2019
Federica BernardiniAndrea Crisanti

Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes

bioRxivNovember 18, 2019
Aditi KulkarniJian-Nong Xu

Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research

ELifeJune 17, 2019
Franziska MohringRobert W Moon

See more papers from this feed

Related Feeds

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Adult Kidney Organoids at Single Cell Resolution

Single-cell RNA sequencing of the adult human kidney transcriptome can provide molecular information about cell-specific responses to environmental variables and disease states. This information can provide a dataset to benchmark human kidney organoids. Discover the latest research on adult kidney organoids at single cell resolution here.

African Trypanosomiasis

African trypanosomiasis, also known as sleeping sickness, is an insect-borne parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei and almost invariably progresses to death unless treated. Discover the latest research on African trypanosomiasis here.

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.


Amoebiasis, infection by the protozoan parasite Entamoeba histolytica, remains a global health problem, despite the availability of effective treatment. Here is the latest research.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.


Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Artificial Cell Models

This feed focuses on biomimetrics, synthetic biology and bio- and tissue-engineering approaches used for modeling human diseases.

© 2019 Meta ULC. All rights reserved