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Crispr In Malaria
CRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.
Top 20 most recent papers
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum
Science Translational MedicineSeptember 18, 2019
Joost SchalkwijkKoen J Dechering
22
13
In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma
Nature BiotechnologySeptember 25, 2019
Lupeng YeSidi Chen
107
5
High density Novel Wolbachia strains in Anopheles species from Guinea
bioRxivSeptember 24, 2019
Claire L. JeffriesThomas Walker
18
Evolution of resistance in vitro reveals a novel mechanism of artemisinin activity in Toxoplasma gondii.
bioRxivAugust 24, 2019
Alex RozenbergL. David David Sibley
4
2
High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation
Scientific ReportsOctober 16, 2019
Chrysanthi TaxiarchiRoberto Galizi
26
Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum
Scientific ReportsNovember 13, 2019
Hai T N BuiTill S Voss
EXP1 is required for organization of the intraerythrocytic malaria parasite vacuole
bioRxivAugust 31, 2019
Timothy NesselJosh R. Beck
5
3
Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection
The Journal of Experimental MedicineOctober 28, 2019
Jing YangErol Fikrig
8
4
4
Cas9-mediated gene-editing in the malaria mosquito Anopheles stephensi by ReMOT Control
bioRxivSeptember 19, 2019
Vanessa M. MaciasJason L. Rasgon
62
A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters
bioRxivNovember 8, 2019
Barbara FasuloNikolai Windbichler
19
An assessment of adult mosquito collection techniques for studying species abundance and diversity in Maferinyah, Guinea
bioRxivSeptember 23, 2019
Cintia Cansado UtrillaThomas Walker
9
A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle
MBioSeptember 17, 2019
Marta TibúrcioMoritz Treeck
42
2
Informed consent and community engagement in open field research: lessons for gene drive science
BMC Medical EthicsJuly 27, 2019
Jerome Amir Singh
4
8
Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti.
bioRxivMay 24, 2019
Ming D LiOmar S. Akbari
41
Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy
Scientific ReportsAugust 19, 2019
Ratna VeeramachaneniNalin S Thakker
15
7
Characterizing the molecular and metabolic mechanisms of insecticide resistance in Anopheles gambiae in Faranah, Guinea
Malaria JournalJuly 17, 2019
Caleb SticaLouisa Alexandra Messenger
7
12
Redkmer: An Assembly-Free Pipeline for the Identification of Abundant and Specific X-Chromosome Target Sequences for X-Shredding by CRISPR Endonucleases
The CRISPR JournalFebruary 1, 2018
Philippos Aris A. Papathanos, Nikolai Windbichler
6
1
19
Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis
Scientific ReportsMarch 26, 2019
Federica BernardiniAndrea Crisanti
4
11
Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes
bioRxivNovember 18, 2019
Aditi KulkarniJian-Nong Xu
6
Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
ELifeJune 17, 2019
Franziska MohringRobert W Moon
36
27