Feed Preview
Fast Growing
Crispr In Malaria
Freakeistein, ShutterstockCRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.
Top 20 most recent papers
Hemocyte-targeted gene expression in the female malaria mosquito using the hemolectin promoter from Drosophila
bioRxivDecember 13, 2019
Emilie PondevilleCatherine Bourgouin
29
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum
Science Translational MedicineSeptember 20, 2019
Joost SchalkwijkKoen J Dechering
22
13
17
Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes
bioRxivNovember 18, 2019
Aditi KulkarniJiannong Xu
11
3
Genome variation and population structure among 1,142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii
bioRxivDecember 9, 2019
Chris S ClarksonDominic P Kwiatkowski
80
Disrupting female flight in the vector Aedes aegypti
bioRxivDecember 2, 2019
Sarah O'Leary, Zach Adelman
18
In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma
Nature BiotechnologySeptember 25, 2019
Lupeng YeSidi Chen
112
5
114
High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation
Scientific ReportsOctober 18, 2019
Chrysanthi TaxiarchiRoberto Galizi
26
13
A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters
bioRxivNovember 8, 2019
Barbara FasuloNikolai Windbichler
20
2
Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti.
bioRxivMay 24, 2019
Ming LiOmar S Akbari
41
1
Antiviral Effectors and Gene Drive Strategies for Mosquito Population Suppression or Replacement to Mitigate Arbovirus Transmission by Aedes aegypti
InsectsJanuary 17, 2020
Adeline E WilliamsKen E Olson
A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle
MBioSeptember 19, 2019
Marta TibúrcioMoritz Treeck
42
2
24
Evolution of resistance in vitro reveals a novel mechanism of artemisinin activity in Toxoplasma gondii.
bioRxivAugust 24, 2019
Alex RozenbergL David Sibley
4
9
Resistance is futile: A CRISPR homing gene drive targeting a haplolethal gene
bioRxivMay 27, 2019
Jackson ChamperPhilipp W. Messer
22
12
Publisher Correction: Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis
Scientific ReportsMay 23, 2019
Federica BernardiniAndrea Crisanti
4
EXP1 is required for organization of the intraerythrocytic malaria parasite vacuole
bioRxivAugust 31, 2019
Timothy NesselJosh R Beck
5
3
Cas9-mediated gene-editing in the malaria mosquito Anopheles stephensi by ReMOT Control
bioRxivSeptember 19, 2019
Vanessa M MaciasJason L Rasgon
62
10
Confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations
bioRxivApril 12, 2019
Héctor M. Sánchez C.John M Marshall
23
High density Novel Wolbachia strains in Anopheles species from Guinea
bioRxivSeptember 24, 2019
Claire L JeffriesThomas Walker
18
4
The abundance and diversity of West Nile virus mosquito vectors in two Regional Units of Greece during the onset of the 2018 transmission season
bioRxivAugust 15, 2019
Marina BisiaThomas Walker
5
Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii
Proceedings of the National Academy of Sciences of the United States of AmericaDecember 7, 2019
Alex RosenbergL David Sibley
12