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CRISPR Ribonucleases Deactivation

CRISPR Ribonucleases Deactivation diagram by A2-33

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on mechanisms that underlie deactivation of CRISPR ribonucleases. Here is the latest research.

Top 20 most recent papers
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Significance of BRCA2 and RB1 co-loss in aggressive prostate cancer progression

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchDecember 3, 2019
Goutam ChakrabortyPhilip W Kantoff
Journal of the American Chemical Society

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic Acid Targets

Journal of the American Chemical SocietyDecember 4, 2019
Ying XiongYi Lu
Scientific Reports

LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels

Scientific ReportsDecember 2, 2019
Jaakko T LeinonenElisabeth I M Widen

Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity

bioRxivDecember 4, 2019
I H GANSJames A. Coffman
Scientific Reports

Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a

Scientific ReportsDecember 2, 2019
Kunwadee PalasinWilaiwan Chotigeat
Nature Communications

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

Nature CommunicationsDecember 6, 2019
Hiroyuki MorisakaTomoji Mashimo

Efficient Homology-directed Repair with Circular ssDNA Donors

bioRxivDecember 5, 2019
Sukanya IyerScot A. Wolfe

Characterization, modelling and mitigation of gene expression burden in mammalian cells

bioRxivDecember 6, 2019
Timothy FreiVelia Siciliano
Scientific Reports

An insulin-like growth factor-like peptide promotes ovarian development in the silkmoth Bombyx mori

Scientific ReportsDecember 5, 2019
Daiki FujinagaAkira Mizoguchi
Harmful Algae

Interaction between cyanophage MaMV-DC and eight Microcystis strains, revealed by genetic defense systems

Harmful AlgaeMay 1, 2019
Juanping WangJindong Zhao
Science Immunology

Clec10a regulates mite-induced dermatitis

Science ImmunologyDecember 6, 2019
Kazumasa KanemaruAkira Shibuya
Molecular Biology Reports

Highly efficient CRISPR-targeting of the murine Hipp11 intergenic region supports inducible human transgene expression

Molecular Biology ReportsDecember 6, 2019
Jill BrowningVincent P Kelly
BMC Genomics

Combining information from genome-wide association and multi-tissue gene expression studies to elucidate factors underlying genetic variation for residual feed intake in Australian Angus cattle

BMC GenomicsDecember 6, 2019
Sara de Las Heras-SaldanaYi-Zhou Chen
International Journal of Molecular Sciences

Dead Cas Systems: Types, Principles, and Applications

International Journal of Molecular SciencesNovember 30, 2019
Sergey BrezginVladimir P Chulanov
PLoS Neglected Tropical Diseases

Serotype distribution and antimicrobial resistance of human Salmonella enterica in Bangui, Central African Republic, from 2004 to 2013

PLoS Neglected Tropical DiseasesDecember 2, 2019
Sebastien BreurecSimon Le Hello
Nucleic Acids Research

Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking

Nucleic Acids ResearchDecember 4, 2019
Xiao-Yu ChenManuel A F V Gonçalves

Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9

ELifeDecember 2, 2019
Hyung Jung OhDavid M. Knipe
Clinical Epigenetics

Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function

Clinical EpigeneticsDecember 4, 2019
Verena DeutschmeyerAntje M Richter
The Journal of Allergy and Clinical Immunology

Sensitization of spinal itch transmission neurons in a mouse model of chronic itch requires an astrocytic factor

The Journal of Allergy and Clinical ImmunologyNovember 21, 2019
Keisuke KogaMakoto Tsuda
Journal of Enzyme Inhibition and Medicinal Chemistry

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation

Journal of Enzyme Inhibition and Medicinal ChemistryDecember 7, 2019
Mohamed M AbdelrahmanClaudiu Trandafir Supuran

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