CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

January 21, 2021
Open Access

The antibiotic negamycin crosses the bacterial cytoplasmic membrane by multiple routes.

Antimicrobial Agents and Chemotherapy
Daniel HörömpöliHeike Brötz-Oesterhelt
January 9, 2021

Carbapenem-Resistant Gram Negative Bacilli Are Predominantly Multidrug or Pan-Drug Resistant

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Priya KannianChandran Priya
January 21, 2021

The benzimidazole SPR719 shows promising concentration-dependent activity and synergy against nontuberculous mycobacteria.

Antimicrobial Agents and Chemotherapy
Lian J PenningsJakko van Ingen
January 13, 2021

Analysis of multidrug resistance in Staphylococcus aureus with a machine learning generated antibiogram

Antimicrobial Agents and Chemotherapy
Casey L CazerYrjö T Gröhn
January 13, 2021

Structural and biochemical characterization of the novel CTX-M-151 extended-spectrum β-lactamase and its inhibition by Avibactam

Antimicrobial Agents and Chemotherapy
Barbara GhiglionePablo Power
January 9, 2021

Fitness Cost of Antibiotic Resistance in Staphylococcus aureus : A Systematic Review

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Abdelaziz TouatiAssia Mairi
January 21, 2021
Open Access

In vivo targeting of E. coli with vancomycin-arginine.

Antimicrobial Agents and Chemotherapy
Lewis F NevilleJacob T Rendell
January 21, 2021

Limited MDR efflux pump overexpression among multidrug-resistant Escherichia coli of ST131.

Antimicrobial Agents and Chemotherapy
Johannes CampWinfried V Kern
January 21, 2021

Carbapenem use is driving the evolution of IMiPenemase (IMP)-1 variants.

Antimicrobial Agents and Chemotherapy
Zishuo ChengMichael W Crowder
January 12, 2021

Colistin-Resistant Enterobacterales Isolated from Chicken Meat in Western Algeria

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Nadia ChaalalAlix Pantel
January 16, 2021
Open Access

Gene Therapy for Drug-Resistant Glioblastoma via Lipid-Polymer Hybrid Nanoparticles Combined with Focused Ultrasound

International Journal of Nanomedicine
Qiang YangYuan Cheng
January 21, 2021

Adaptive Processes Change as Multiple Functions Evolve.

Antimicrobial Agents and Chemotherapy
Portia M MiraMiriam Barlow
January 21, 2021
Open Access

Synergistic rifabutin and colistin reduce emergence of resistance when treating Acinetobacter baumannii.

Antimicrobial Agents and Chemotherapy
Jiaqi ChengBrian Luna
January 20, 2021
Comment / Editorial

The Future of Microbial Drug Resistance

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Ivo G Boneca
January 21, 2021

Modulation of Human Beta-Defensin 2 Expression by Pathogenic Neisseria meningitidis and Commensal Lactobacilli.

Antimicrobial Agents and Chemotherapy
Gabriela M WassingAnn-Beth Jonsson
January 21, 2021

In vitro resistance and evolution of resistance to tavaborole in Trichophyton rubrum.

Antimicrobial Agents and Chemotherapy
Diletta MazzantiniEmilia Ghelardi

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