CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

January 19, 2022

Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer.

Journal of Experimental & Clinical Cancer Research : CR
Zhang YangRen-Wang Peng
January 19, 2022
Retraction

Retraction for Shin and Ko, "A Plasmid Bearing the blaCTX-M-15 Gene and Phage P1-Like Sequences from a Klebsiella pneumoniae Isolate".

Antimicrobial Agents and Chemotherapy
Juyoun Shin, Kwan Soo Ko
January 18, 2022
Preprint
Open Access

Activation of the Integrated Stress Response overcomes multidrug resistance in FBXW7-deficient cells

BioRxiv : the Preprint Server for Biology
L. Sanchez-BurgosOscar Fernandez-Capetillo
January 17, 2022
Review

Anti-CRISPR proteins as a therapeutic agent against drug-resistant bacteria.

Microbiological Research
Pallavi Vyas, Harish
January 15, 2022

Acknowledgment of Reviewers 2021.

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
January 14, 2022

High Prevalence and Fitness of IncFrepB Carrying qnrS1 in Hypervirulent Klebsiella pneumoniae Isolates.

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Si ChenYang Liu
January 14, 2022

Comparative Genomic Analysis of the Human Variant of Methicillin-Resistant Staphylococcus aureus CC398 in Japan and Korea.

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Hiroshi KanekoHidemasa Nakaminami
January 12, 2022
Preprint
Open Access

TEX13B is important for germ cell development and male fertility

BioRxiv : the Preprint Server for Biology
U K KumarKumarasamy Thangaraj
January 12, 2022
Open Access

Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells.

International Journal of Molecular Sciences
Robert J Rabelo-FernándezPablo E Vivas-Mejia
January 12, 2022
Review

Hairy CRISPR: Genome Editing in Plants Using Hairy Root Transformation.

Plants
Alexey S KiryushkinKirill N Demchenko
January 12, 2022
Open Access

DSTYK Enhances Chemoresistance in Triple-Negative Breast Cancer Cells.

Cells
Stella C OgbuYong Jiang
January 12, 2022

Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association.

Nature Communications
Chia-Chin WuP Andrew Futreal
January 10, 2022
Preprint
Open Access

Genomic features underlie the co-option of SVA transposons as cis-regulatory elements in human pluripotent stem cells

BioRxiv : the Preprint Server for Biology
S. M. BarnadaMarco Trizzino
January 11, 2022

Circulating Tumor Cell Lines: an Innovative Tool for Fundamental and Translational Research.

Journal of Visualized Experiments : JoVE
Guillaume BelthierJulie Pannequin

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