CRISPR & Single Cell Analyses

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on CRISPR-Cas applications relevant to single cell analyses. Here is the latest research.

August 23, 2020
Open Access

Frataxin gene editing rescues Friedreich's ataxia pathology in dorsal root ganglia organoid-derived sensory neurons

Nature Communications
Pietro Giuseppe MazzaraVania Broccoli
September 17, 2020
Open Access

Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells

Science Advances
Hiroshi OchiaiItoshi Nikaido
August 25, 2020
Open Access

Advances in Viral Diagnostic Technologies for Combating COVID-19 and Future Pandemics

SLAS Technology
Ninghao Zhu, Pak Kin Wong
November 28, 2020
Open Access

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes

Science
Xin JinPaola Arlotta
August 19, 2020
Open Access

Uncoupling gene expression noise along the central dogma using genome engineered human cell lines

Nucleic Acids Research
Tyler QuartonLeonidas Bleris
November 24, 2020

Muscle differentiation induced by p53 signaling pathway-related genes in myostatin-knockout quail myoblasts

Molecular Biology Reports
Jeong-Woong ParkTae Sub Park
August 20, 2020
Open Access

Gene editing and elimination of latent herpes simplex virus in vivo

Nature Communications
Martine AubertKeith R Jerome
December 6, 2020
Open Access

Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity

Cell Systems
Woo Jun ShimNathan J Palpant
August 21, 2020

Visualization of Chromatin Dynamics by Live Cell Microscopy Using CRISPR/Cas9 Gene Editing and ANCHOR Labeling

Methods in Molecular Biology
Ezio T FokMusa M Mhlanga
September 29, 2020
Open Access

Optimal Design of Single-Cell Experiments within Temporally Fluctuating Environments

Complexity
Zachary R FoxBrian Munsky
November 8, 2020
Review

Single-cell transfection technologies for cell therapies and gene editing

Journal of Controlled Release : Official Journal of the Controlled Release Society
Bastien DuckertMaarten Fauvart
November 6, 2020
Open Access

Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and Lobular Breast Cancer Cells

Cancer Research
Fangyuan ChenAdrian V Lee
January 15, 2021
Preprint
Open Access

High-resolution characterization of gene function using single-cell CRISPR tiling screen

ResearchSquare
Lu YangChun-Wei Chen
October 28, 2020

Integrated Ca2+ flux and AFM force analysis in human iPSC-derived cardiomyocytes

Biological Chemistry
Andrey V MalkovskiyAntje Ebert
September 22, 2020
Open Access

Generation of Nonhuman Primate Model of Cone Dysfunction through In Situ AAV-Mediated CNGB3 Ablation

Molecular Therapy. Methods & Clinical Development
Qiang LinZi-Bing Jin

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