CRISPR & Single Cell Analyses

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on CRISPR-Cas applications relevant to single cell analyses. Here is the latest research.

January 14, 2022
Open Access

Probabilistic modeling of ambient noise in single-cell omics data

BioRxiv : the Preprint Server for Biology
C. ShengAntoine de Weck
January 14, 2022

Pooled genetic perturbation screens with image-based phenotypes.

Nature Protocols
David FeldmanPaul C Blainey
January 12, 2022
Open Access

CRISPR/Cas9 Genome Editing vs. Over-Expression for Fluorescent Extracellular Vesicle-Labeling: A Quantitative Analysis.

International Journal of Molecular Sciences
Karin StrohmeierMario Mairhofer
January 11, 2022

Comparative Studies of Renin-Null Zebrafish and Mice Provide New Functional Insights.

Scott HoffmannJohn Mullins
January 11, 2022

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants.

Journal of Visualized Experiments : JoVE
Cara E MoravecFrancisco Pelegri
January 9, 2022

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells.

Biotechnology Letters
Xiang-Xing ZhuDong-Sheng Tang
January 7, 2022

ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis.

Paul ChengThomas Quertermous
January 4, 2022

An RNA-Based Theory of Natural Universal Computation.

Journal of Theoretical Biology
Hessameddin Akhlaghpour
January 2, 2022
Open Access

Multiplex labeling and manipulation of endogenous neuronal proteins using sequential CRISPR/Cas9 gene editing

BioRxiv : the Preprint Server for Biology
W. J. DroogersA. P. de Jong
December 31, 2021

Identification of cis-regulatory elements associated with MAPT expression in human induced pluripotent stem cell derived neural cells.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Brianne B RogersJ Nicholas Cochran
December 31, 2021

Lineage recording in human cerebral organoids.

Nature Methods
Zhisong HeBarbara Treutlein
December 25, 2021
Open Access

YAP1 Is a Potential Predictive Molecular Biomarker for Response to SMO Inhibitor in Medulloblastoma Cells.

Gustavo Alencastro Veiga CruzeiroElvis Terci Valera
December 23, 2021
Open Access

Method of Microglial DNA-RNA Purification from a Single Brain of an Adult Mouse.

Methods and Protocols
Md Obayed RaihanJames E Porter

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