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CRISPR & Single Cell Analyses

CRISPR & Single Cell Analyses diagram by Kk5725
Kk5725

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on CRISPR-Cas applications relevant to single cell analyses. Here is the latest research.

Top 20 most recent papers
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Significance of BRCA2 and RB1 co-loss in aggressive prostate cancer progression

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchDecember 3, 2019
Goutam ChakrabortyPhilip W Kantoff
37
Nature Communications

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

Nature CommunicationsDecember 6, 2019
Hiroyuki MorisakaTomoji Mashimo
34
4
Cell

High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity

CellNovember 26, 2019
Ian SetliffIvelin S. Georgiev
128
1
bioRxiv

GO: A functional reporter system to identify and enrich base editing activity

bioRxivDecember 3, 2019
Alyna KattiLukas E. Dow
33
bioRxiv

Relationships and genome evolution of polyploid Salix species revealed by RAD sequencing data

bioRxivDecember 4, 2019
Natascha Dorothea WagnerElvira Hörandl
5
Nature Communications

The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status

Nature CommunicationsNovember 28, 2019
Ricky M TriggSuzanne Dawn Turner
21
3
The European Respiratory Journal

Genetic Landscape of Adult Langerhans Cell Histiocytosis with Lung Involvement

The European Respiratory JournalDecember 5, 2019
Fanelie JouenneAbdellatif Tazi
1
Cell Reports

IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development

Cell ReportsDecember 3, 2019
Amy LiTyler E Jacks
53
bioRxiv

Efficient Homology-directed Repair with Circular ssDNA Donors

bioRxivDecember 5, 2019
Sukanya IyerScot A. Wolfe
4
bioRxiv

Multi-colour DNA-qPAINT reveals how Csk nano-clusters regulate T-cell receptor signalling

bioRxivNovember 27, 2019
Sabrina SimoncelliDylan M. Owen
15
bioRxiv

Minimized double guide RNA libraries enable scale-limited CRISPR/Cas9 screens

bioRxivNovember 29, 2019
Elin Madli PeetsLeopold Parts
63
Proceedings of the National Academy of Sciences of the United States of America

A cis -element within the ARF locus mediates repression of p16INK4A expression via long-range chromatin interactions

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 9, 2019
Yang ZhangChun Liang Li
Nature Methods

Isolating live cells after high-throughput, long-term, time-lapse microscopy

Nature MethodsNovember 25, 2019
Scott LuroJohan Owe Paulsson
Nucleic Acids Research

Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking

Nucleic Acids ResearchDecember 4, 2019
Xiao-Yu ChenManuel A F V Gonçalves
1
Methods in Molecular Biology

Isolation and Characterization of MAIT Cells from Human Tissue Biopsies

Methods in Molecular BiologyDecember 4, 2019
Daniela Di BlasiLucia Mori
Science China. Life Sciences

Recent advances in mammalian reproductive biology

Science China. Life SciencesNovember 29, 2019
Lu WenZi-Jiang Chen
1
Methods in Molecular Biology

Isolation and Characterization of MAIT Cells from Tumor Tissues

Methods in Molecular BiologyDecember 4, 2019
William RodinMarianne Quiding Järbrink
Antimicrobial Agents and Chemotherapy

Linker editing of pneumococcal lysin ClyJ conveys improved bactericidal activity

Antimicrobial Agents and ChemotherapyNovember 25, 2019
Hang YangHong-Ping Wei
PloS One

Genome-wide histone modification profiling of inner cell mass and trophectoderm of bovine blastocysts by RAT-ChIP

PloS OneNovember 25, 2019
Tõnis OrgAnts Kurg
1
Forensic Science International. Genetics

Comparison of CE- and MPS-based analyses of forensic markers in a single cell after whole genome amplification

Forensic Science International. GeneticsNovember 29, 2019
Man ChenJiang Wei Yan
2

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