CRISPRi Screens for Antibiotics

The CRISPR-Cas system is a gene editing technique that can be used for high-throughput genome-wide screens to identify modes of actions of novel antibiotics. Here is the latest research.

October 16, 2020
Open Access

A Flexible, Pooled CRISPR Library for Drug Development Screens

The CRISPR Journal
Maximilian BlanckBenedict C S Cross
October 10, 2020

Comparison of serial optical coherence tomography imaging following aggressive stent expansion technique: insight from the MECHANISM study

The International Journal of Cardiovascular Imaging
Wataru SasakiYoshihiro Morino
October 20, 2020
Open Access

CEN-tools: an integrative platform to identify the contexts of essential genes

Molecular Systems Biology
Sumana SharmaEvangelia Petsalaki
October 24, 2020
Open Access

High-throughput genotyping of high-homology mutant mouse strains by next-generation sequencing

Methods : a Companion to Methods in Enzymology
Diane GleesonEdward Ryder
October 26, 2020
Review

Cellular and Molecular Mechanisms in the Development of a Cleft Lip and/or Cleft Palate; Insights from Zebrafish (Danio rerio)

The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
Devi Sewvandini Atukorala Atukorallaya, Ravindra Kumar Ratnayake
October 13, 2020
Preprint
Open Access

CRISPR-Based Transcriptional Activation Tool for Silent Genes in Filamentous Fungi

BioRxiv : the Preprint Server for Biology
L. MozsikArnold J. M. Driessen
October 23, 2020

Liquid drop of DNA libraries reveals total genome information

Proceedings of the National Academy of Sciences of the United States of America
Stanislav S TerekhovAlexander G Gabibov
October 8, 2020
Review
Open Access

Drug Development and the Use of Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Disease Modeling and Drug Toxicity Screening

International Journal of Molecular Sciences
Paz OvicsOfer Binah
October 25, 2020

Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells

Proceedings of the National Academy of Sciences of the United States of America
Xiaolong WeiMazhar Adli
October 15, 2020
Preprint
Open Access

Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection

BioRxiv : the Preprint Server for Biology
Ryan A FlynnAnsuman T Satpathy
October 20, 2020
Preprint
Open Access

Study on Suitable Analysis Method for HIV-1 Non-catalytic Integrase Inhibitor

ResearchSquare
Ki Hoon ParkYoung Bong Kim
October 22, 2020
Preprint
Open Access

Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction

BioRxiv : the Preprint Server for Biology
K. J. CondonDavid M. Sabatini
October 22, 2020
Open Access

Oregano Phytocomplex Induces Programmed Cell Death in Melanoma Lines via Mitochondria and DNA Damage

Foods
Valentina NanniAngelo Gismondi
October 12, 2020
Open Access

High-Fidelity Drug Induced Liver Injury Screen Using Human PSC-derived Organoids

Gastroenterology
Tadahiro ShinozawaTakanori Takebe
October 24, 2020
Open Access

CNCDatabase: a database of non-coding cancer drivers

Nucleic Acids Research
Eric Minwei LiuEkta Khurana
October 24, 2020

Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing

The CRISPR Journal
Misha AngristKevin Davies
October 15, 2020
Review
Open Access

Biosensing based on field-effect transistors (FET): Recent progress and challenges

Trends in Analytical Chemistry : TRAC
Deniz SadighbayanEbrahim Ghafar-Zadeh
October 23, 2020
Review
Open Access

Applications of 3D Bioprinted-Induced Pluripotent Stem Cells in Healthcare

International Journal of Bioprinting
Soja Saghar Soman, Sanjairaj Vijayavenkataraman

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