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Cryogenic Electron Microscopy

Cryogenic Electron Microscopy diagram by undefined

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

Top 20 most recent papers

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex

ScienceOctober 31, 2019
Rosalie E LawrenceRoberto Zoncu

Structure of the human metapneumovirus polymerase phosphoprotein complex

NatureNovember 7, 2019
Junhua PanJulien Lescar
PLoS Biology

Building de novo cryo-electron microscopy structures collaboratively with citizen scientists

PLoS BiologyNovember 1, 2019
Firas KhatibScott Horowitz

ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer

bioRxivNovember 12, 2019
Xiaoshan ShiJames H Hurley

Monitoring Dynamics of Large Membrane Proteins by 19F Paramagnetic Longitudinal Relaxation: Domain Movement in a Glutamate Transporter Homolog

bioRxivNovember 5, 2019
Yun HuangOlga Boudker
Nature Communications

Active DNA unwinding and transport by a membrane-adapted helicase nanopore

Nature CommunicationsNovember 8, 2019
Ke SunJia Geng

Visualization of the HIV-1 Env Glycan Shield Across Scales

bioRxivNovember 12, 2019
Zachary T BerndsenAndrew B. Ward
Nature Communications

Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis

Nature CommunicationsNovember 1, 2019
Matthias SchmidtMarcus Fändrich

The resolution revolution in cryoEM requires new sample preparation procedures: A rapid pipeline to high resolution maps of yeast FAS

bioRxivNovember 4, 2019
Mirko JoppeWerner Kuehlbrandt
Proceedings of the National Academy of Sciences of the United States of America

Correction for Huet et al., Capsid expansion of bacteriophage T5 revealed by high resolution cryoelectron microscopy

Proceedings of the National Academy of Sciences of the United States of AmericaNovember 11, 2019

Allosteric coupling between alpha-rings of the 20S proteasome

bioRxivNovember 7, 2019
Zanlin YuYifan Cheng

Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome

StructureNovember 7, 2019
Yoshimasa TakizawaHitoshi Kurumizaka

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a novel macromolecular assembly

bioRxivNovember 8, 2019
Xingjian XuDavid J. Weber

Topaz-Denoise: general deep denoising models for cryoEM

bioRxivNovember 12, 2019
Tristan BeplerBonnie Berger

Uncovering patterns of atomic interactions in static and dynamic structures of proteins

bioRxivNovember 13, 2019
A. J. VenkatakrishnanRon O. Dror

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

bioRxivNovember 2, 2019
Rory HendersonS M Sabbir Alam

Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex

CellNovember 5, 2019
Kuang ShenDavid M. Sabatini

Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome

bioRxivNovember 13, 2019
Evan J WordenCynthia P Wolberger
Scientific Reports

Calculation of absolute binding free energies between the hERG channel and structurally diverse drugs

Scientific ReportsNovember 12, 2019
Tatsuki NegamiTohru Terada
Journal of Molecular Biology

Mobile loops and electrostatic interactions maintainthe flexible tail tube of bacteriophage lambda

Journal of Molecular BiologyNovember 8, 2019
Patricia L CampbellAlexis G E Huet

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