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Cryogenic Electron Microscopy
Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.
Top 20 most recent papers
Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex
ScienceOctober 31, 2019
Rosalie E LawrenceRoberto Zoncu
108
Structure of the human metapneumovirus polymerase phosphoprotein complex
NatureNovember 7, 2019
Junhua PanJulien Lescar
10
3
Building de novo cryo-electron microscopy structures collaboratively with citizen scientists
PLoS BiologyNovember 1, 2019
Firas KhatibScott Horowitz
ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer
bioRxivNovember 12, 2019
Xiaoshan ShiJames H Hurley
19
Monitoring Dynamics of Large Membrane Proteins by 19F Paramagnetic Longitudinal Relaxation: Domain Movement in a Glutamate Transporter Homolog
bioRxivNovember 5, 2019
Yun HuangOlga Boudker
4
Active DNA unwinding and transport by a membrane-adapted helicase nanopore
Nature CommunicationsNovember 8, 2019
Ke SunJia Geng
21
Visualization of the HIV-1 Env Glycan Shield Across Scales
bioRxivNovember 12, 2019
Zachary T BerndsenAndrew B. Ward
17
Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis
Nature CommunicationsNovember 1, 2019
Matthias SchmidtMarcus Fändrich
5
The resolution revolution in cryoEM requires new sample preparation procedures: A rapid pipeline to high resolution maps of yeast FAS
bioRxivNovember 4, 2019
Mirko JoppeWerner Kuehlbrandt
18
Correction for Huet et al., Capsid expansion of bacteriophage T5 revealed by high resolution cryoelectron microscopy
Proceedings of the National Academy of Sciences of the United States of AmericaNovember 11, 2019
1
Allosteric coupling between alpha-rings of the 20S proteasome
bioRxivNovember 7, 2019
Zanlin YuYifan Cheng
2
Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome
StructureNovember 7, 2019
Yoshimasa TakizawaHitoshi Kurumizaka
78
Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a novel macromolecular assembly
bioRxivNovember 8, 2019
Xingjian XuDavid J. Weber
16
Topaz-Denoise: general deep denoising models for cryoEM
bioRxivNovember 12, 2019
Tristan BeplerBonnie Berger
35
Uncovering patterns of atomic interactions in static and dynamic structures of proteins
bioRxivNovember 13, 2019
A. J. VenkatakrishnanRon O. Dror
7
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements
bioRxivNovember 2, 2019
Rory HendersonS M Sabbir Alam
7
Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex
CellNovember 5, 2019
Kuang ShenDavid M. Sabatini
24
2
1
Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome
bioRxivNovember 13, 2019
Evan J WordenCynthia P Wolberger
3
Calculation of absolute binding free energies between the hERG channel and structurally diverse drugs
Scientific ReportsNovember 12, 2019
Tatsuki NegamiTohru Terada
Mobile loops and electrostatic interactions maintainthe flexible tail tube of bacteriophage lambda
Journal of Molecular BiologyNovember 8, 2019
Patricia L CampbellAlexis G E Huet