Cytochrome Activity

This feed focuses on cytochromes, including cytochrome C and the cytochromes P450 (CYP) enzyme system, and their involvement in the activation and inactivation of drugs.

October 22, 2021

iCYP-MFE: Identifying Human Cytochrome P450 Inhibitors Using Multitask Learning and Molecular Fingerprint-Embedded Encoding.

Journal of Chemical Information and Modeling
Thanh-Hoang Nguyen-VoLy Le
October 22, 2021

Colchicine in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

The Lancet. Respiratory Medicine
RECOVERY Collaborative Group
October 22, 2021

Environmentally relevant lead (Pb) water concentration induce toxicity in zebrafish (Danio rerio) larvae.

Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP
Andrew KatabaMayumi Ishizuka
October 22, 2021

Refined CYP2E1∗ Template∗∗ system to decipher the ligand-interactions.

Drug Metabolism and Pharmacokinetics
Yasushi YamazoeKouichi Yoshinari
October 22, 2021

Effects of the moderate CYP3A4 inhibitor erythromycin on the pharmacokinetics of palbociclib: a randomized cross-over trial in patients with breast cancer.

Clinical Pharmacology and Therapeutics
Laura Molenaar-KuijstenDutch Pharmacology Oncology Group (DPOG, www.dpog.nl)
October 22, 2021

Determining the Exposure Threshold for Levonorgestrel Efficacy Using an Integrated Model Based Meta-Analysis (MBMA) Approach.

Clinical Pharmacology and Therapeutics
Karthik LingineniStephan Schmidt
October 23, 2021
Open Access

Microsatellites reveal that genetic mixing commonly occurs between invasive fall armyworm populations in Africa.

Scientific Reports
Amy J WithersKenneth Wilson
October 23, 2021

Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism.

The Journal of Biological Chemistry
Meredith R McGuirePeter J Espenshade
October 23, 2021

Application of liquid chromatography coupled to data-independent acquisition mass spectrometry for the metabolic profiling of N-ethyl heptedrone.

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Monica MazzarinoFrancesco Botrè
October 24, 2021

Emergence of Parafilaria bovicola in Austria.

Animals : an Open Access Journal From MDPI
Alexandra HundHans-Peter Fuehrer
October 24, 2021

Revealing Pathways Associated with Feed Efficiency and Meat Quality Traits in Slow-Growing Chickens.

Animals : an Open Access Journal From MDPI
Chotima PoompramunAmélie Juanchich
October 24, 2021

Distribution and Molecular Diversity of Whitefly Species Colonizing Cassava in Kenya.

Insects
Florence M MungutiAgnes W Mwango'mbe

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