Cytoskeleton spans the cytoplasm and interconnects the cell nucleus with the extracellular matrix, thereby forming a structural link between molecules involved in cell communication on the one hand, and gene expression on the other. Since the cytoskeleton is involved in virtually all cellular processes, abnormalities in this essential cellular component frequently result in disease. Discover the latest research on cytoskeleton and disease here.
Contractile forces generated by the actin-myosin cytoskeleton are critical for morphogenesis, but the cellular and molecular mechanisms of contraction have been elusive for many cell shape changes and movements. Here is the latest research on the roles of actin and myosin in cell movement.
Actin-binding proteins are a component of the actin cytoskeleton that play essential roles in cellular functions such as regulation of actin polymerization, maintenance of cell polarity, gene expression regulation, cell motility and many more functions. Discover the latest research on actin-binding proteins here.
Cytoskeletal motors of the dynein, kinesin and myosin superfamilies maintain and adapt subcellular organelle organization to meet functional demands and support the vesicular transport of material between organelles. Here is the latest research on cytoskeletal and motor biophysics.
The cytoskeleton is a dynamic network of interlinking protein filaments that extends from the plasma membrane to the nucleus. Here is the latest research.
The cytoskeleton is a dynamic system that is involved in numerous cellular functions. The dynamic cytoskeleton has a close relationship with formation and trafficking of vesicles, spindle localization, cell compartmentation and more. Here is the latest research on cytoskeletal dynamics.
A dynamic cytoskeleton is critical for the generation of cell polarity. This feed focuses on cell polarity and the cytoskeleton, including actin and microtubular cytoskeletal organization.
The cytoskeleton is composed of three main proteins that help maintain cell structures. Localization of proteins is crucial for understanding how proteins function within a cell. Here is the latest research on the cytoskeleton in protein localization.
Multiprotein adhesion structures allow the interaction of a cell with the extracellular matrix comprised of extracellular molecules that ensure tissue integrity and play a role in cell growth, migration, and differentiation. Here is the latest research.
Intermediate filaments provide mechanical support for cells and tissues. Discover the latest research on intermediate filaments here.
Microtubule organization and dynamics are regulated by microtubule-associated proteins that interact with microtubules to regulate dynamic instability. Here is the latest research on microtubules and microtubule-associated proteins.