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CZI Human Cell Atlas Seed Network

CZI Human Cell Atlas Seed Network diagram by undefined

The aim of the Human Cell Atlas (HCA) is to build reference maps of all human cells in order to enhance our understanding of health and disease. The Seed Networks for the HCA project aims to bring together collaborators with different areas of expertise in order to facilitate the development of the HCA. Find the latest research from members of the HCA Seed Networks here.

Top 20 most recent papers
Nature

Circular ecDNA promotes accessible chromatin and high oncogene expression

NatureNovember 20, 2019
Sihan WuPaul S. Mischel
546
106
5
1
3
1
Science Signaling

The human secretome

Science SignalingNovember 26, 2019
Mathias UhlénAsa Sivertsson
150
1
1
Science

Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice

ScienceNovember 22, 2019
Iván M MoyaGeorg Halder
54
7
1
Nature Methods

Orchestrating single-cell analysis with Bioconductor

Nature MethodsDecember 2, 2019
Robert A AmezquitaStephanie C. Hicks
226
1
bioRxiv

Demand for Multiplatform and Meta-analytic Approaches in Transcriptome Profiling

bioRxivDecember 2, 2019
Dóra TombáczZsolt Boldogköi
9
Science

Massively multiplex chemical transcriptomics at single cell resolution

ScienceDecember 5, 2019
Sanjay SrivatsanCole Trapnell
254
7
Nature Biotechnology

Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia

Nature BiotechnologyDecember 2, 2019
Jeffrey M. GranjaWilliam James Greenleaf
288
1
1
bioRxiv

A limited set of transcriptional programs define major histological types and provide the molecular basis for a cellular taxonomy of the human body

bioRxivNovember 27, 2019
Alessandra BreschiRoderic Guigó
25
Nature Methods

Analysis of the Human Protein Atlas Image Classification competition

Nature MethodsNovember 30, 2019
Wei OuyangEmma K Lundberg
212
bioRxiv

Selective metabolic redundancy of Gpi1 allows for specific inhibition of inflammatory Th17 cells

bioRxivNovember 29, 2019
Lin WuDan R. Littman
11
1
bioRxiv

Frequent extrachromosomal oncogene amplification drives aggressive tumors

bioRxivNovember 28, 2019
Hoon KimRoel G.W. Verhaak
82
Nature Communications

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

Nature CommunicationsNovember 29, 2019
Ayshwarya SubramanianAnna Greka
61
1
Nature

Gene expression cartography

NatureNovember 20, 2019
Mor NitzanNikolaus Rajewsky
419
10
4
Neuron

Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes

NeuronNovember 20, 2019
Nicholas M. TranJoshua R. Sanes
32
bioRxiv

A saturating mutagenesis CRISPR-Cas9 mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in embryonic stem cells

bioRxivNovember 22, 2019
Matthew C. CanverPartha Pratim Das
8
bioRxiv

Structural modularity of the XIST ribonucleoprotein complex

bioRxivNovember 24, 2019
Zhipeng LuHoward Y. Chang
24
Nature

c-Jun overexpression in CAR T cells induces exhaustion resistance

NatureDecember 4, 2019
Rachel Christina LynnCrystal L. Mackall
137
3
4
Cell Stem Cell

Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress

Cell Stem CellDecember 5, 2019
Kevin Matthew ByrdScott E Williams
Nature Communications

Senescent cell turnover slows with age providing an explanation for the Gompertz law

Nature CommunicationsDecember 2, 2019
Omer KarinOmer Karin
154
bioRxiv

Protein products of non-stop mRNA disrupt nucleolar homeostasis

bioRxivNovember 22, 2019
Zoe A DavisOnn Brandman
26

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