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CZI Neurodegeneration Challenge Network

CZI Neurodegeneration Challenge Network diagram by Frank Gaillard, Wikimedia
Frank Gaillard, Wikimedia

The Neurodegeneration Challenge Network aims to provide funding for and to bring together researchers studying neurodegenerative diseases. Find the latest research from the NDCN grantees here.

Top 20 most recent papers
Molecular Psychiatry

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

Molecular PsychiatryOctober 21, 2019
Joshua C M BisLindsay A Farrer
1
1
3
Science

To help aging populations, classify organismal senescence

ScienceNovember 1, 2019
Stuart Richard Gilbert CalimportGeorge M. Church
158
12
Science

Technological challenges and milestones for writing genomes

ScienceOctober 18, 2019
Nili OstrovHille Tekotte
189
6
1
50
Nature Communications

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

Nature CommunicationsNovember 25, 2019
Dimitrios PapaioannouRamiro Garzon
Science Translational Medicine

A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough

Science Translational MedicineOctober 23, 2019
Rushdy AhmadMichael A. Gillette
78
19
1
bioRxiv

Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP-43-C pathology

bioRxivNovember 20, 2019
Valentina BorghesaniMaria Luisa Gorno-Tempini
2
Cell

Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense

CellDecember 3, 2019
Nicole Y. LaiIsaac M Chiu
120
6
1
bioRxiv

Thrombospondin-1 Promotes Circuit-Specific Synapse Formation via β1-Integrin

bioRxivDecember 9, 2019
Sehwon KohCagla Eroglu
10
Stem Cell Reports

A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies

Stem Cell ReportsOctober 22, 2019
Celeste M. KarchTau Consortium Stem Cell Group
58
2
23
bioRxiv

17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease and progressive supranuclear palsy converge on altered glial regulation

bioRxivNovember 30, 2019
Kathryn R BowlesAlison M. Goate
13
bioRxiv

Machine learning on drug-specific data to predict small molecule teratogenicity

bioRxivNovember 30, 2019
Anup P. ChallaDavid M. Aronoff
16
Acta Neuropathologica

Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration

Acta NeuropathologicaNovember 20, 2019
Eri SaijoByron W Caughey
JAMA Network Open

Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease

JAMA Network OpenDecember 2, 2019
Jorge J Llibre-GuerraEric Martin McDade
bioRxiv

Non-stem progenitors enable coordinated changes in gut epithelial cell-type composition

bioRxivNovember 13, 2019
Laura E SanmanSteven J. Altschuler
2
3
Alzheimer's & Dementia : the Journal of the Alzheimer's Association

Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study

Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationOctober 17, 2019
Frederic BrosseronAETIONOMY study group
7
1
1
12
Scientific Reports

Polyneuropathy in Gaucher disease type 1 and 3 - a descriptive case series

Scientific ReportsOctober 25, 2019
Mattias AndréassonPer Svenningsson
Neuron

Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy

NeuronSeptember 18, 2019
Jesse A. BrownWilliam W. Seeley
77
12
2
23
Nature Protocols

Imaging neuromodulators with high spatiotemporal resolution using genetically encoded indicators

Nature ProtocolsNovember 15, 2019
Tommaso PatriarchiLin Tian
96
39
bioRxiv

CRISPR-based screens uncover determinants of immunotherapy response and potential combination therapy strategies

bioRxivNovember 7, 2019
Poornima RamkumarMartin Kampmann
Nature Methods

Unified rational protein engineering with sequence-based deep representation learning

Nature MethodsOctober 23, 2019
Ethan C. AlleyGeorge M. Church
258
4
4
194
3

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