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CZI Neurodegeneration Challenge Network

CZI Neurodegeneration Challenge Network diagram by Frank Gaillard, Wikimedia
Frank Gaillard, Wikimedia

The Neurodegeneration Challenge Network aims to provide funding for and to bring together researchers studying neurodegenerative diseases. Find the latest research from the NDCN grantees here.

Top 20 most recent papers
Nature Reviews. Neuroscience

Tissue clearing and its applications in neuroscience

Nature Reviews. NeuroscienceJanuary 4, 2020
Hiroki R UedaPhilipp J Keller
212
2
Nature Neuroscience

Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins

Nature NeuroscienceJanuary 8, 2020
Simon ErlendssonJohn A G Briggs
378
bioRxiv

In vivo multi-dimensional information-keeping in Halobacterium salinarum

bioRxivFebruary 15, 2020
Joe DavisGeorge M Church
2
Science Translational Medicine

APOE genotype regulates pathology and disease progression in synucleinopathy

Science Translational MedicineFebruary 7, 2020
Albert A DavisDavid M Holtzman
45
8
Alzheimer's & Dementia : the Journal of the Alzheimer's Association

Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning

Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationFebruary 12, 2020
Nicolai FranzmeierMichael Ewers
13
1
Nature Cell Biology

RNA-targeting CRISPR systems from metagenomic discovery to transcriptomic engineering

Nature Cell BiologyFebruary 5, 2020
Aaron A SmargonGene W Yeo
23
93
1
bioRxiv

Pharmaceutical-grade Rigosertib is a Microtubule-destabilizing Agent

bioRxivJanuary 29, 2020
Marco JostJonathan S Weissman
2
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology

Mechanism of microglia promoting retinal ganglion cell death in vitro

[Zhonghua yan ke za zhi] Chinese journal of ophthalmologyJanuary 16, 2020
F LiY H Zhuo
1
The Journal of Biological Chemistry

A synthetic heparinoid blocks tau aggregate cell uptake and amplification

The Journal of Biological ChemistryJanuary 25, 2020
Barbara E StopschinskiMarc I Diamond
6
1
Alzheimer's & Dementia : the Journal of the Alzheimer's Association

Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN)

Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationJanuary 9, 2020
Andrew J AschenbrennerDominantly Inherited Alzheimer Network
17
1
1
Science

Chromatin accessibility dynamics in a model of human forebrain development

ScienceJanuary 25, 2020
Alexandro E TrevinoSergiu Pasca
234
4
Trends in Genetics : TIG

Omics in Neurodegenerative Disease: Hope or Hype?

Trends in Genetics : TIGJanuary 15, 2020
Maria E Diaz-Ortiz, Alice S Chen-Plotkin
30
1
bioRxiv

Low-N protein engineering with data-efficient deep learning

bioRxivJanuary 24, 2020
Surojit BiswasGeorge M Church
124

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