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Dana-Farber Cancer Institute

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Dana-Farber Cancer Institute focuses on advancing cancer tratment through supporting clinical trials and translational research. Follow this feed to stay up to date on research from this institute.

Top 20 most recent papers
Nature

Longitudinal molecular trajectories of diffuse glioma in adults

NatureNovember 20, 2019
Floris P BarthelGLASS Consortium
165
4
1
1
bioRxiv

Oncologic Therapy Shapes the Fitness Landscape of Clonal Hematopoiesis

bioRxivNovember 20, 2019
Kelly L BoltonElli Papaemmanuil
139
Nature Genetics

Stalled developmental programs at the root of pediatric brain tumors

Nature GeneticsNovember 27, 2019
Selin JessaClaudia L. Kleinman
83
6
Science

Clonal hematopoiesis in human aging and disease

ScienceNovember 1, 2019
Siddhartha Jaiswal, Benjamin L Ebert
184
1
1
Nature Medicine

Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans

Nature MedicineNovember 7, 2019
Nicolás Gómez-BanoyJames C Lo
98
11
1
Blood

Genomic Analyses of PMBL Reveal New Drivers and Mechanisms of Sensitivity to PD-1 Blockade

BloodOctober 28, 2019
Bjoern ChapuyMargaret A Shipp
3
bioRxiv

Selective metabolic redundancy of Gpi1 allows for specific inhibition of inflammatory Th17 cells

bioRxivNovember 29, 2019
Lin WuDan R. Littman
11
1
American Journal of Hematology

Increased mitochondrial apoptotic priming with targeted therapy predicts clinical response to re-induction chemotherapy

American Journal of HematologyDecember 5, 2019
Jacqueline S GarciaAnthony G Letai
Annals of Surgical Oncology

Staging for Breast Cancer Patients Receiving Neoadjuvant Chemotherapy: Utility of Incorporating Biologic Factors

Annals of Surgical OncologyOctober 30, 2019
Min YiElizabeth Ann Mittendorf
bioRxiv

Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer

bioRxivNovember 10, 2019
Adrienne G. WaksNikhil Wagle
31
bioRxiv

Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

bioRxivNovember 20, 2019
Inchul YouAlex Toker
3
Genes & Development

The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis

Genes & DevelopmentNovember 16, 2019
Matthew G OserWilliam G. Kaelin
11
Blood Advances

Non-del(5q) myelodysplastic syndromes-associated loci detected by SNP-array genome-wide association meta-analysis

Blood AdvancesNovember 19, 2019
Kathy L McGrawAlan F List
2
Annals of the New York Academy of Sciences

Leveraging insights into cancer metabolism-a symposium report

Annals of the New York Academy of SciencesDecember 2, 2019
Jennifer CableWilliam G. Kaelin
1
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyNovember 13, 2019
Bradley Alexander McGregorToni K. Choueiri
111
3
1
Blood

Preliminary Safety and Efficacy Results from a Phase 2 Study of Acalabrutinib, Venetoclax and Obinutuzumab in Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL)

BloodNovember 13, 2019
Benjamin L LampsonMatthew S Davids
1
Cell Reports

CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer

Cell ReportsNovember 19, 2019
Justin H HwangWilliam Chun Hahn
33
3
Genome Biology

Scaling computational genomics to millions of individuals with GPUs

Genome BiologyNovember 1, 2019
Amaro Taylor-WeinerGad Getz
101
Cancer Discovery

Resistance mechanisms to SYK inhibition in acute myeloid leukemia

Cancer DiscoveryNovember 26, 2019
Anjali CremerKimberly Stegmaier
7
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology

Night-shift work duration and risk of colorectal cancer according to IRS1 and IRS2 expression

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive OncologyOctober 30, 2019
Yan Fen ShiXue-Hong Zhang
1

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