Dana-Farber Cancer Institute

Dana-Farber Cancer Institute focuses on advancing cancer tratment through supporting clinical trials and translational research. Follow this feed to stay up to date on research from this institute.

June 20, 2020

Chromatin Complexes Maintain Self-Renewal of Myeloid Progenitors in AML: Opportunities for Therapeutic Intervention

Stem Cell Reports
Hannah J Uckelmann, Scott A Armstrong
June 17, 2020

Targeted protein degradation as a powerful research tool in basic biology and drug target discovery

Nature Structural & Molecular Biology
Tao WuEric S Fischer
June 3, 2020
Open Access

Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Nature Medicine
Kirsten L BryantChanning J Der
June 6, 2020
Open Access

CoMut: Visualizing integrated molecular information with comutation plots

Jett CrowdisEliezer M Van Allen
July 1, 2020

Pharmacological disruption of the Notch transcription factor complex

Proceedings of the National Academy of Sciences of the United States of America
Rajwinder LehalFreddy Radtke
June 6, 2020

Barcoded microbial system for high-resolution object provenance

Jason QianMichael Springer
June 14, 2020
Open Access

Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant

Nature Communications
Tarek H MouhieddineIrene M Ghobrial
June 5, 2020

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

Mikołaj SłabickiBenjamin L Ebert
June 27, 2020
Open Access

Potent Neutralizing Monoclonal Antibodies Directed to Multiple Epitopes on the SARS-CoV-2 Spike

BioRxiv : the Preprint Server for Biology
Lihong LiuDavid D Ho
July 1, 2020
Open Access

Large Nanodiscs: A Potential Game Changer in Structural Biology of Membrane Protein Complexes and Virus Entry

Frontiers in Bioengineering and Biotechnology
Krishna M Padmanabha DasMahmoud L Nasr
June 7, 2020

Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus

Molecular Cell
Marco MineoE Antonio Chiocca
June 20, 2020

Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface

ACS Medicinal Chemistry Letters
Mingxing TengNathanael Schiander Gray

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Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Head And Neck Squamous Cell Carcinoma

Squamous cell carcinomas account for >90% of all tumors in the head and neck region. Head and neck squamous cell carcinoma incidence has increased dramatically recently with little improvement in patient outcomes. Here is the latest research on this aggressive malignancy.

Signaling in Adult Neurogenesis

Neural stem cells play a critical role in the production of neuronal cells in neurogenesis is of great importance. Of interest is the role signalling mechanisms in adult neurogenesis. Discover the latest research on signalling in adult neurogenesis.

Psychiatric Chronotherapy

Psychiatric Chronotherapy considers the circadian rhythm as a major factor for optimizing therapeutic efficacy of psychiatric interventions. Discover the latest research on Psychiatric Chronotherapy here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

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