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Dana-Farber Cancer Institute

Dana-Farber Cancer Institute diagram by David A. Litman, Shutterstock
David A. Litman, Shutterstock

Dana-Farber Cancer Institute focuses on advancing cancer tratment through supporting clinical trials and translational research. Follow this feed to stay up to date on research from this institute.

Top 20 most recent papers
Nature Reviews. Cancer

A framework for advancing our understanding of cancer-associated fibroblasts

Nature Reviews. CancerJanuary 26, 2020
Erik SahaiZena Werb
45
Cancer Cell

Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

Cancer CellJanuary 15, 2020
Kari J KurppaPasi A Jänne
88
Blood

Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results

BloodDecember 27, 2019
John C ByrdRichard R Furman
4
Cancer Cell

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

Cancer CellDecember 31, 2019
Hua ZhangKwok-Kin Wong
91
1
Nature Genetics

Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation

Nature GeneticsJanuary 22, 2020
Anindita BasakVijay G Sankaran
86
bioRxiv

Varying co-factor requirements for MAML1-dependent transcription at different Notch-responsive target genes

bioRxivJanuary 14, 2020
Julia M RogersStephen Blacklow
1
British Journal of Cancer

A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma

British Journal of CancerDecember 21, 2019
Amin H NassarDavid J Kwiatkowski
28
Nature Genetics

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer

Nature GeneticsJanuary 15, 2020
Guotai XuEneda Toska
73
bioRxiv

Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through Growth Differentiation Factor 3

bioRxivJanuary 14, 2020
Jessica A HallAlexander Banks
13
bioRxiv

Robust nucleation control via crisscross polymerization of DNA slats

bioRxivDecember 12, 2019
Dionis MinevWilliam M Shih
22
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Efficacy and Safety of Duvelisib Following Disease Progression on Ofatumumab in Patients with Relapsed/Refractory CLL or SLL in the DUO Crossover Extension Study

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchJanuary 23, 2020
Matthew DavidsUlrich Jäger
2
Nature Communications

Rapid and deep-scale ubiquitylation profiling for biology and translational research

Nature CommunicationsJanuary 19, 2020
Namrata D UdeshiSteven A Carr
54
ACS Nano

Extrusion of RNA from a DNA-Origami-Based Nanofactory

ACS NanoJanuary 11, 2020
Jaeseung HahnWilliam M Shih
22
Nature Structural & Molecular Biology

Defining the landscape of ATP-competitive inhibitor resistance residues in protein kinases

Nature Structural & Molecular BiologyJanuary 12, 2020
N S PerskyC M Johannessen
30
bioRxiv

Implications of TP53 Allelic State for Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

bioRxivDecember 19, 2019
Elsa BernardElli Papaemmanuil
98
Leukemia & Lymphoma

Pembrolizumab monotherapy in patients with primary refractory classical hodgkin lymphoma who relapsed after salvage autologous stem cell transplantation and/or brentuximab vedotin therapy: KEYNOTE-087 subgroup analysis

Leukemia & LymphomaJanuary 7, 2020
Pier Luigi ZinzaniCraig H Moskowitz
5
Nucleic Acids Research

Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair

Nucleic Acids ResearchJanuary 26, 2020
Niu LiAlan D D'Andrea
2
bioRxiv

Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis

bioRxivDecember 19, 2019
Jennifer ElliottSebla B. Kutluay
3
Diabetologia

An exploratory, randomised, placebo-controlled, 14 day trial of the soluble guanylate cyclase stimulator praliciguat in participants with type 2 diabetes and hypertension

DiabetologiaDecember 21, 2019
John P HanrahanAlbert T Profy
3
Nature Communications

Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer

Nature CommunicationsJanuary 22, 2020
Ritika TiwariBushra Ateeq
57
1

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