Dana-Farber Cancer Institute

Dana-Farber Cancer Institute focuses on advancing cancer tratment through supporting clinical trials and translational research. Follow this feed to stay up to date on research from this institute.

September 3, 2020
Open Access

Rapid 'mix and read' assay for scalable detection of SARS-CoV-2 antibodies in patient plasma

MedRxiv : the Preprint Server for Health Sciences
H. YueEric S Fischer
September 15, 2020
Case Report

WNT-Activated Medulloblastomas With Hybrid Molecular Subtypes

JCO Precision Oncology
Jeffrey HelgagerKeith L Ligon
September 1, 2020
Open Access

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

BioRxiv : the Preprint Server for Biology
C. J. FrangiehBenjamin Izar
August 21, 2020
Open Access

A phase 1b/2 study of duvelisib in combination with FCR (DFCR) for frontline therapy for younger CLL patients

Matthew S DavidsJennifer R Brown
September 3, 2020

Comparing the knowledge gap hypothesis in the United States and Singapore: The case of nanotechnology

Public Understanding of Science
Shirley S HoKasisomayajula Viswanath
September 2, 2020

Genomic predictors of good outcome, recurrence or progression in High grade T1 non-muscle invasive bladder cancer

Cancer Research
Joaquim BellmuntDavid J Kwiatkowski
August 19, 2020
Open Access

Modular HUWE1 architecture serves as hub for degradation of cell-fate decision factors

BioRxiv : the Preprint Server for Biology
M. HunkelerEric S Fischer
August 23, 2020

The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies

Cancer Discovery
Angela SuAlexandre Puissant
September 6, 2020
Open Access

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Dragana VuckovicNicole Soranzo
September 4, 2020
Open Access

Fibrinogen anchors enable efficient multiplexed patterning of active proteins and subcellular control of membrane-receptor distribution

BioRxiv : the Preprint Server for Biology
J. L. WatsonEmmanuel Derivery
August 26, 2020
Open Access

Allogeneic stem cell transplantation for chronic lymphocytic leukemia in the era of novel agents

Blood Advances
Lindsey E RoekerAnthony R Mato
August 19, 2020

Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer

Nature Chemical Biology
Ann M CathcartLoren D Walensky
September 3, 2020

STING cyclic dinucleotide sensing originated in bacteria

Benjamin R MorehousePhilip J Kranzusch
September 2, 2020

Axillary Management After Neoadjuvant Endocrine Therapy for Hormone Receptor-Positive Breast Cancer

Annals of Surgical Oncology
Olga KantorTari A King
September 13, 2020
Open Access

Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors

Nature Genetics
Anton G HenssenAlex Kentsis

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Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

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