Managing and storing research data in formats that can be easily retrieved and shared, and publishing a variety of data outputs, including source data, improves reproducibility of research. Find the latest insights on data sharing here.
Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.
The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.
Biodiversity refers to the variety and variability of life on Earth. Biodiversity is typically a measure of variation at the genetic, species, and ecosystem level.Discover the latest research on biodiversity data here.
Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.
Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a genome-wide technique used to map histone marks and protein binding (ie transcription factors) on chromatin. This can reveal insight into the regulation and dynamics of gene expression. Discover the latest research on ChIP-seq here.
Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.
Computational benchmarking studies aim to rigorously compare the performance of different bioinformatic methods using well-characterized datasets. Discover the latest research on Benchmarking Computational Methods here.
Computational pathology is an approach to diagnosis that incorporates multiple sources of data (e.g., pathology, radiology, clinical, molecular and lab operations); uses mathematical models to generate diagnostic inferences; and presents clinically actionable knowledge to customers. This vision goes beyond an informatics-centric view and leverages the core competency of pathology and the ability to effectively communicate clinically actionable knowledge. Discover the latest research on computational pahtology here.
Expression Quantitative Trait Loci (eQTL) analysis is the identification of specific or groups of genetic variants that affect gene expression levels within the cell. Discover the latest research on Expression Quantitative Trait Loci Analysis here.
Genetic epidemiology examines the role of genetic factors in determining health and disease in populations and the interaction between these genetic factors with environmental factors. Here is the latest research on the genetic epidemiology of complex multifactorial diseases like cancer.