DDX3X Syndrome

DDX3X syndrome is caused by a spontaneous mutation at conception that primarily affects girls due to its location on the X-chromosome. DDX3X syndrome has been linked to intellectual disabilities, seizures, autism, low muscle tone, brain abnormalities, and slower physical developments. Here is the latest research.

July 29, 2010
Open Access

Paternally biased X inactivation in mouse neonatal brain

Genome Biology
Xu WangAndrew G Clark
December 10, 2017

A CK1 FRET biosensor reveals that DDX3X is an essential activator of CK1ε

Journal of Cell Science
Christine DoldeBeat Suter
May 11, 2018
Open Access

Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development

BioRxiv : the Preprint Server for Biology
Ashley L LennoxElliott H Sherr
December 20, 2011

The X chromosome and immune associated genes

Journal of Autoimmunity
Ilaria BianchiPietro Invernizzi
August 21, 2018

DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome

Acta Neuropathologica
Tareq A JuratliPriscilla K Brastianos
March 1, 2012
Open Access

Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controls

Gender Medicine
Yingfang TianFrank R Sharp
August 27, 2013

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cells

Cancer Immunology, Immunotherapy : CII
Jun KoshioIchiei Narita
March 13, 2014
Open Access

RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma

Molecules and Cells
Rebecca Bish, Christine Vogel
August 4, 2015
Open Access

Dynamics of gene silencing during X inactivation using allele-specific RNA-seq

Genome Biology
Hendrik MarksHendrik G Stunnenberg
November 7, 2015

Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors

Journal of Chemical Information and Modeling
Roberta FaziMaurizio Botta
February 2, 2018
Open Access

Dengue Virus Capsid Interacts with DDX3X-A Potential Mechanism for Suppression of Antiviral Functions in Dengue Infection

Frontiers in Cellular and Infection Microbiology
Rinki KumarGuruprasad R Medigeshi
March 19, 2015

Escape from X inactivation varies in mouse tissues

PLoS Genetics
Joel B BerletchXinxian Deng
March 1, 2019

Further delineation of DDX3X syndrome

Clinical Dysmorphology
Nicolas M ChanesYves Lacassie
July 6, 2019

Expansion of phenotype of DDX3X syndrome: six new cases

Clinical Dysmorphology
Bryony BealHimanshu Goel
December 10, 2009
Open Access

Dosage regulation of the active X chromosome in human triploid cells

PLoS Genetics
Xinxian DengChristine M Disteche

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