Deficiency of Adenosine Deaminase 2 (DADA2)

First reported in 2014, deficiency of adenosine deaminase 2 (DADA2) is a genetic disease affecting the blood vessels and the immune system. This disease results in a range of symptoms that may include recurrent strokes, severe systemic inflammation, immune deficiency, and damage to many of the body's tissues and organs. As an extremely rare condition, there is still much to learn. Find the latest research on DADA2 in this feed.

February 24, 2021

Systematic evaluation of nine monogenic autoinflammatory diseases reveals common and disease-specific correlations with allergy-associated features.

Annals of the Rheumatic Diseases
Daniella Muallem SchwartzPamela Frischmeyer-Guerrerio
February 23, 2021

Clinical Features and Outcomes of Childhood Polyarteritis Nodosa: A Single Referral Center Experience.

Modern Rheumatology
Nilüfer TekgözBanu Acar
February 21, 2021
Review

Biologic drugs in the treatment of polyarteritis nodosa and deficit of adenosine deaminase 2: A narrative review.

Autoimmunity Reviews
Edoardo ConticiniLuca Cantarini
February 1, 2021
Open Access

Novel ADA2 Compound Heterozygous Mutations Resulting in Deficiency of Adenosine Deaminase 2 in a Pair of Siblings.

Journal of Clinical Immunology
Li GuoQing Zhou
January 30, 2021
Open Access

Polyarteritis Nodosa: A Systematic Review of Test Accuracy and Benefits and Harms of Common Treatments.

ACR Open Rheumatology
Yih Chang LinReem A Mustafa
December 30, 2020
Preprint
Open Access

Diagnosis and management of Adenosine Deaminase 2 Deficiency children: the experience from China

ResearchSquare
Wei WangHongmei Song
September 7, 2020

Deficiency of Adenosine Deaminase 2 in Adults and Children: Experience From India.

Arthritis & Rheumatology
Aman SharmaPui Y Lee
August 28, 2020
Review
Open Access

The Many Faces of a Monogenic Autoinflammatory Disease: Adenosine Deaminase 2 Deficiency

Current Rheumatology Reports
Jennifer Lee Kendall, Jason M Springer
August 17, 2020

Deficiency of Adenosine Deaminase 2 (DADA2) - A New Autoinflammatory Disease with Multisystem Features

Indian Pediatrics
Raju Khubchandani, Ivona Aksentijevich
July 25, 2020

Dysregulation in B-cell responses and T follicular helper cell function in ADA2 deficiency patients.

European Journal of Immunology
Francesca SchenaMarco Gattorno
July 12, 2020
Open Access

Adenosine deaminase 2 activity negatively correlates with age during childhood

Pediatric Rheumatology Online Journal
Sarah M BowersKelly L Brown
July 9, 2020

Deficiency of Adenosine Deaminase 2 (DADA2): Hidden Variants, Reduced Penetrance, and Unusual Inheritance

Journal of Clinical Immunology
Oskar SchnappaufIvona Aksentijevich

Sign up to follow this feed and discover related papers.

Related Feeds

22q11 Deletion Syndrome

22q11.2 deletion syndrome, also known as DiGeorge syndrome, is a congenital disorder caused as a result of a partial deletion of chromosome 22. Here is the latest research.

4H Leukodystrophy

4H Lekodystrophy involves hypomyelination, hypogonadotropic hypogonadism and hypodontia. It is also known as POLR-3Related Leukodystrophy. 4H syndrome symptoms include delayed or abnormal puberty, issues with central nervous system signal transmission, abnormal development of teeth, and symptoms tend to progressively get worse over time. There is not yet a known cure.

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

Adult Polyglucosan Body Disease

Adult polyglucosan body disease (APBD) is a rare autosomal recessive disease characterized by defects in the glycogen brancher enzyme 1 (GBE1) gene. Discover the latest research on APBD here.

Alzheimer's Disease: Amyloid Beta

Alzheimer's disease is a neurodegenerative disease associated with the accumulation of amyloid plaques in the brain; these plaques are comprised of amyloid beta deposits. Here is the latest research in this field.

Amyloid Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a progressive nervous system disease associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

Angelman Syndrome

Angelman syndrome is a neurogenetic imprinting disorder caused by loss of the maternally inherited UBE3A gene and is characterized by generalized epilepsy, limited expressive speech, sleep dysfunction, and movement disorders. Here is the latest research.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research.

Bullous Pemphigoid

Bullous pemphigoid is a chronic and relatively benign subepidermal blistering disease usually of the elderly and without histopathologic acantholysis. Discover the latest research on bullous pemphigoid here.

CLOVES Syndrome

Congenital, Lipomatous, Overgrowth, Vascular Malformations, Epidermal Nevi and Spinal/Skeletal Anomalies and/or Scoliosis (CLOVES) syndrome is a rare genetic disorder caused by mutations in the PIK3CA gene. Symptoms include blood vessel abnormalities, small tissue tumors, skin legions and spinal abnormalities. Here is the latest research.

© 2021 Meta ULC. All rights reserved
/feed-previews/deficiency-of-adenosine-deaminase-2/aadddb2d-42ef-4e11-8643-5e7d895d670d