Delivery of Editing Machinery

Genome editing technologies enable the editing of genes to create or correct mutations, thus have immense therapeutic potential. However, editing efficiency is limited by the delivery of editing machinery. Here is the latest research pertaining to the delivery of editing machinery.

September 18, 2020

Degradation Dependent Protein Release from Enzyme Sensitive Injectable Glycol Chitosan Hydrogel

Tissue Engineering. Part a
Shalini V GohilLakshmi Nair
July 4, 2020

An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth

Proceedings of the National Academy of Sciences of the United States of America
Vania VidimarKarla J F Satchell
April 30, 2020
Open Access

Genomic Analysis Using Bayesian Methods under Different Genotyping Platforms in Korean Duroc Pigs

Animals : an Open Access Journal From MDPI
Jungjae LeeTaejeong Choi
April 12, 2020

Proteolistics: A Protein Delivery Method

Methods in Molecular Biology
Susana Martin-Ortigosa, Kan Wang
June 12, 2020

Targeting the undruggable: emerging technologies in antibody delivery against intracellular targets

Expert Opinion on Drug Delivery
Suchada NiamsuphapChristopher B Howard
May 5, 2020

Targeted Delivery of Recombinant Heat Shock Protein 27 to Cardiomyocytes Promotes Recovery from Myocardial Infarction

Molecular Pharmaceutics
Nahyeon KimSang-Kyung Lee
July 17, 2020

Cationic Lipid-based Intracellular Delivery of Bacterial Effectors for Rewiring Malignant Cell Signaling

Angewandte Chemie
Shaojun YangPeng R Chen
May 30, 2020

Cell-penetrating peptide enhanced insulin buccal absorption

International Journal of Pharmaceutics
You XuVictor C Yang
March 25, 2020

An in vitro and in vivo study of the brain-targeting effects of an epidermal growth factor-functionalized cholera toxin-like chimeric protein

Journal of Controlled Release : Official Journal of the Controlled Release Society
Huafeng HeHuaqian Wang
March 14, 2020
Open Access

Polyethylenimine based magnetic nanoparticles mediated non-viral CRISPR/Cas9 system for genome editing

Scientific Reports
S S RohiwalK Stieger
September 21, 2020

Nanosponges as protein delivery systems: insulin, a case study

International Journal of Pharmaceutics
Silvia Lucia AppletonRoberta Cavalli
September 13, 2020

Protein Transport Studied by a Model Asymmetric Membrane Army Arranged in a Dimple Chip

Methods in Molecular Biology
Xin Li, Min Chen
August 13, 2020
Preprint
Open Access

CD83 Expression Regulates Antibody Production in Response to Influenza A Virus Infection

ResearchSquare
Madhav AkauliyaHyung-Joo Kwon
June 21, 2020
Open Access

Hypoxia-instructed pro-protein therapy assisted with self-catalyzed nanozymogen

Angewandte Chemie
Xudong LiLichen Yin
August 2, 2020
Open Access

Bivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
R Yu KiselevaC F Greineder
February 19, 2020

A Novel Transdermal Protein Delivery Strategy via Electrohydrodynamic Coating of PLGA Microparticles onto Microneedles

ACS Applied Materials & Interfaces
Ukrit AngkawinitwongGareth R Williams

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