Diabetes & Alzheimer's Disease

Epidemiological data indicate that a significant portion of the diabetic population exhibits brain changes that are hallmarks of Alzheimer’s disease and vascular dementia. However, direct biological links remain incompletely understood. Here is the latest research in this area.

January 15, 2022

Capillary Stalling: A Mechanism of Decreased Cerebral Blood Flow in AD/ADRD.

Journal of Experimental Neurology
Reece CrumplerFan Fan
January 14, 2022
Review

On-going consequences of in utero exposure of Pb: An epigenetic perspective.

Journal of Applied Toxicology : JAT
Fahim Rejanur TasinChanchal Mandal
January 13, 2022
Open Access

Is there an association between non-alcoholic fatty liver disease and cognitive function? A systematic review.

BMC Geriatrics
Elena S GeorgeSze-Yen Tan
January 13, 2022
Review

Reduced nicotinamide adenine dinucleotide phosphate in redox balance and diseases: a friend or foe?

Acta Pharmacologica Sinica
Nirmala KojuRui Sheng
January 13, 2022

Age and Ageing journal 50th anniversary commentary seriesWhy illness is more important than disease in old age.

Age and Ageing
Marcel G M Olde RikkertG M E E Geeske Peeters
January 13, 2022
Review

Inflammation in obesity, diabetes, and related disorders.

Immunity
Theresa V RohmMarc Y Donath
January 12, 2022
Review
Open Access

A Growing Link between Circadian Rhythms, Type 2 Diabetes Mellitus and Alzheimer's Disease.

International Journal of Molecular Sciences
Xuemin PengYan Yang
January 12, 2022
Open Access

Divergent Effect of Central Incretin Receptors Inhibition in a Rat Model of Sporadic Alzheimer's Disease.

International Journal of Molecular Sciences
Jelena Osmanovic BarilarMelita Salkovic-Petrisic
January 12, 2022
Review

Implementing Complementary Approaches to Shape the Mechanism of α-Synuclein Oligomerization as a Model of Amyloid Aggregation.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Marco GiampàVeronica I Dodero
January 12, 2022
Review

Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Md Mominur RahmanMd Sahab Uddin
January 12, 2022

Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer's disease.

Alzheimer's Research & Therapy
Jiansong FangFeixiong Cheng
January 12, 2022

Severe Hypoglycemia Increases Dementia Risk and Related Mortality: A Nationwide, Population-Based Cohort Study.

The Journal of Clinical Endocrinology and Metabolism
Eugene HanYong-Ho Lee
January 10, 2022
Review

Mechanistic insight into the role of metformin in Alzheimer's disease.

Life Sciences
Mehdi SanatiAmirhossein Sahebkar
January 11, 2022

Trials and Treatments for Vascular Brain Health: Risk Factor Modification and Cognitive Outcomes.

Stroke; a Journal of Cerebral Circulation
Miia KivipeltoKristine Yaffe

Sign up to follow this feed and discover related papers.

Related Feeds

3D Cellular Models of Brain and Neurodegeneration

Brain organoids are three-dimensional in vitro cellular models of the brain that can recapitulate many processes such as the neurodevelopment. In addition, these organoids can be combined with other cell types, such as neurons and astrocytes to study their interactions in assembloids. Disease processes can also be modeled by induced pluripotent stem cell-derived organoids and assembloids from patients with neurodegenerative disorders. Discover the latest research on the models here.

ALS & FTD: TDP-43

TAR DNA-binding protein 43 (TDP-43) is a pathological protein identified in sporadic Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). Here are the latest discoveries pertaining to TDP-43 and these diseases.

ALS: Genetics

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Pathogenic Mechanisms

Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS: Phenotypes

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized phenotypically by progressive muscle weakness. Clinical phenotypes of ALS can be classified based on the pattern, level, and area of onset (e.g. bulbar, cervical, lumbar). Here is the latest research investigating phenotypes of ALS.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here is the latest research on ALS and prions.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research in this field.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS) is associated with the death of neurons that control voluntary muscles. This feed followes the latest research into therapies for this progressive neurodegenerative disease.

Age-related Dementia

Dementias are a group of conditions, including Alzheimer's disease, vascular dementia, and frontotemporal dementia, characterized by deficiencies in cognitive abilities. Age-related dementia refers to dementias that occur in older individuals, usually 60+ years old, in contrast to early-onset dementia. Follow the latest research on age-related dementia here.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

© 2022 Meta ULC. All rights reserved
/feed-previews/diabetes-and-alzheimers-disease/1fd339f4-7778-4cc3-82b4-3f71b2b8f654