DNA Helicases

DNA helicases are motor enzymes that move along the DNA phosphodiester backbone separating two DNA strands using energy derived from ATP hydrolysis. They are essential for several cellular processes including DNA replication and transcription. Here is the latest research.

January 21, 2022
Open Access

Discovery of a neuromuscular syndrome caused by biallelic variants in ASCC3.

HGG Advances
Divya NairElizabeth J Bhoj
January 20, 2022

Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments.

Proceedings of the National Academy of Sciences of the United States of America
Aviv MeirEric C Greene
January 20, 2022

CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism.

Proceedings of the National Academy of Sciences of the United States of America
Nina Y YaoMichael E O'Donnell
January 20, 2022

Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.

Brain : a Journal of Neurology
Annapoorna KannanLaxman Gangwani
January 19, 2022

Natural transformation protein ComFA exhibits single-stranded DNA translocase activity.

Journal of Bacteriology
Hannah R FosterBriana M Burton
January 17, 2022

PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response.

Advanced Science
Xinwei GengSongmin Ying
January 17, 2022
Case Report

Werner syndrome in a Lebanese family.

American Journal of Medical Genetics. Part a
Batoul JaafarDavor Lessel
January 14, 2022

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1.

The Journal of Clinical Investigation
Bassam Abu-LibdehGrant S Stewart
January 14, 2022

Mitochondrial RNA processing defect caused by a SUPV3L1 mutation in two siblings with a novel neurodegenerative syndrome.

Journal of Inherited Metabolic Disease
S L van EsveldJ N Spelbrink
January 13, 2022

Chl1 helicase controls replication fork progression by regulating dNTP pools.

Life Science Alliance
Amandine BattéHaico van Attikum
January 12, 2022
Preprint
Open Access

Strand-switching mechanism of Pif1 helicase induced by its collision with a G-quadruplex embedded in dsDNA

BioRxiv : the Preprint Server for Biology
J. Valle-OreroJean-Baptiste Boule
January 12, 2022

Mechanism for inverted-repeat recombination induced by a replication fork barrier.

Nature Communications
Léa Marie, Lorraine S Symington
January 11, 2022
Preprint
Open Access

Single-molecule mapping of replisome progression

BioRxiv : the Preprint Server for Biology
C. ClaussinIestyn Whitehouse
January 10, 2022

Identification and characterization of a new germline-specific marker vasa gene and its promoter in the giant freshwater prawn Macrobrachium rosenbergii.

Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
Xue-Ying HeGao-Feng Qiu

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