DNA Repair & Genome Editing

Development of gene editing techniques, including CRISPR and TALENs, has relied on mechanisms that underlie DNA repair and genome stability pathways. This feed focuses on the role of DNA repair mechanisms in gene editing and genetic engineering.

July 17, 2020

CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells

Computational and Structural Biotechnology Journal
Gue-Ho HwangSangsu Bae
July 12, 2020

Optogenetics and CRISPR: A New Relationship Built to Last

Methods in Molecular Biology
Jan MathonyDominik Niopek
July 23, 2020

Recent developments in enhancing the efficiency of CRISPR/Cas9- mediated knock-in in animals

Yi chuan = Hereditas
Guo Ling LiXian Wei Zhang
July 14, 2020

A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene

American Journal of Physiology. Renal Physiology
Ryan J CorneliusJames A McCormick
July 25, 2020
Preprint
Open Access

Mtg16-dependent repression of E protein activity is required for early lymphopoiesis

BioRxiv : the Preprint Server for Biology
P. AcharyaKristy R Stengel
July 30, 2020
Open Access

Adaptation induced by self-targeting in a type I-B CRISPR-Cas system

The Journal of Biological Chemistry
Aris-Edda StachlerAnita Marchfelder
July 11, 2020

Cleaving DNA by nanozymes

Journal of Materials Chemistry. B, Materials for Biology and Medicine
Ruiqin Fang, Juewen Liu
July 17, 2020
Open Access

CRISPR/Cas9-mediated double knockout of SRPK1 and SRPK2 in a nasopharyngeal carcinoma cell line

Cancer Reports
Pongphol PrattapongTavan Janvilisri
July 12, 2020

The novel insight into the outcomes of CRISPR/Cas9 editing intra- and inter-species

International Journal of Biological Macromolecules
Jiasong ChangQingyou Xia
July 11, 2020
Open Access

A Genetic Map of the Response to DNA Damage in Human Cells

Cell
Michele OlivieriDaniel Durocher
July 26, 2020
Preprint
Open Access

Effects of individual base-pairs on in vivo target search and destruction kinetics of small RNA

BioRxiv : the Preprint Server for Biology
A. PoddarTaekjip Ha
July 9, 2020
Preprint
Open Access

Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiota

BioRxiv : the Preprint Server for Biology
July 17, 2020
Open Access

Engineering the Effector Domain of the Artificial Transcription Factor to Improve Cellulase Production by Trichoderma reesei

Frontiers in Bioengineering and Biotechnology
Qing-Shan MengFeng-Wu Bai
July 30, 2020

Rapidly formed stable and aligned dense collagen gels seeded with Schwann cells support peripheral nerve regeneration

Journal of Neural Engineering
Papon MuangsanitJames Benjamin Phillips
July 9, 2020
Open Access

Comprehensive Constitutional Genetic and Epigenetic Characterization of Lynch-Like Individuals

Cancers
Estela DámasoGabriel Capellá
July 17, 2020
Review
Open Access

Nanoparticle-Mediated Drug Delivery for Treatment of Ischemic Heart Disease

Frontiers in Bioengineering and Biotechnology
Chengming FanWuqiang Zhu
July 30, 2020
Review

Three-dimensional scaffold-free microtissues engineered for cardiac repair

Journal of Materials Chemistry. B, Materials for Biology and Medicine
Alejandra Patino-GuerreroMehdi Nikkhah
July 27, 2020

Identification and Isolation of Human LGR5+ Cells Using an Antibody-Based Strategy

Methods in Molecular Biology
Michael K DameJustin A Colacino

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