DNA Repair & Genome Editing

Development of gene editing techniques, including CRISPR and TALENs, has relied on mechanisms that underlie DNA repair and genome stability pathways. This feed focuses on the role of DNA repair mechanisms in gene editing and genetic engineering.

January 16, 2022

Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress.

Proceedings of the National Academy of Sciences of the United States of America
Yiji LiaoKexin Xu
January 11, 2022
Preprint
Open Access

Optimized cell culture conditions promote ex-vivo manipulation and expansion of primitive hematopoietic stem cells for therapeutic gene editing.

BioRxiv : the Preprint Server for Biology
R. RaiAlessia Cavazza
January 11, 2022
Review

Stem Cell Mimicking Nanoencapsulation for Targeting Arthritis.

International Journal of Nanomedicine
Min Jun ShinDongwoo Khang
January 11, 2022

A Versatile and Efficient Plant Protoplast Platform for Genome Editing by Cas9 RNPs.

Frontiers in Genome Editing
Wenzhi JiangJen Sheen
January 11, 2022

Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects.

Blood
Laëtitia KermassonPatrick Revy
January 6, 2022
Preprint
Open Access

CRISPR/Cas9 knock-in strategy to evaluate phospho-regulation of SAMHD1

BioRxiv : the Preprint Server for Biology
M. SchüsslerR. König
January 6, 2022

[Development of a CRISPR/Cpf1 gene editing system in silkworm Bombyx mori].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Zhanqi DongMinhui Pan
January 5, 2022
Preprint
Open Access

Conserved meiotic mechanisms in the cnidarian Clytia hemisphaerica revealed by Spo11 knockout

BioRxiv : the Preprint Server for Biology
C. MunroJean-Ren&eacute Huynh
January 4, 2022
Review

Targeted Gene Knockouts by Protoplast Transformation in the Moss Physcomitrella patens.

Frontiers in Genome Editing
Lei Zhu
January 4, 2022
Review
Open Access

Circular RNA Expression for Dilated Cardiomyopathy in Hearts and Pluripotent Stem Cell-Derived Cardiomyocytes.

Frontiers in Cell and Developmental Biology
Yiyu ZhangRong Chang
January 3, 2022
Review

CRISPR/Cas gene-editing technology and its advances in dentistry.

Biochimie
Patricia Alejandra Chavez-GranadosRene Garcia-Contreras
January 2, 2022
Preprint
Open Access

oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera

BioRxiv : the Preprint Server for Biology
B. ClarkM. Emilia Santos
January 1, 2022
Preprint
Open Access

Thylakoid grana stacking revealed by multiplex genome editing of LHCII encoding genes

BioRxiv : the Preprint Server for Biology
Z. GuardiniRoberto Bassi

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