DNA Repair in Primary Cell Systems

Cells are subjected to several DNA damaging events on a daily basis which results in the induction of DNA damage signaling and repair cascades to ensure genomic integrity. Here is the latest research on DNA damage signaling and repair mechanisms in primary cells.

August 29, 2020
Open Access

Recent advances in the nucleolar responses to DNA double-strand breaks

Nucleic Acids Research
Lea Milling KorsholmDorthe Helena Larsen
September 1, 2020
Open Access

RecT recombinase expression enables efficient gene editing in Enterococcus

BioRxiv : the Preprint Server for Biology
V. ChenHoward C Hang
September 5, 2020

Modulation of DNA double-strand break repair as a strategy to improve precise genome editing

Ujjayinee Ray, Sathees C Raghavan
September 10, 2020
Open Access

Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases

Frontiers in Molecular Neuroscience
Joseph Edward RittinerBoris Kantor
September 15, 2020

Detection of CRISPR/Cas9-Generated Off-Target Effect by Integration-Defective Lentiviral Vector

Methods in Molecular Biology
Xiaoling WangJiing-Kuan Yee
September 8, 2020
Open Access

Comprehensive classification of ABC ATPases and their functional radiation in nucleoprotein dynamics and biological conflict systems

Nucleic Acids Research
Arunkumar KrishnanL Aravind
September 6, 2020
Open Access

Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo

Nucleic Acids Research
Zhengping ShaoShan Zha
September 12, 2020
Open Access

Rapid, precise quantification of large DNA excisions and inversions by ddPCR

Scientific Reports
Hannah L WatryLuke M Judge
September 10, 2020
Open Access

Functional classification of prostate cancer‑associated miRNAs through CRISPR/Cas9‑mediated gene knockout

Molecular Medicine Reports
Fu-Neng JiangWei-De Zhong
September 6, 2020
Open Access

SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response

Nucleic Acids Research
Andreas MundHans Will
September 26, 2020
Open Access

Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy

Frontiers in Oncology
Vitaly ChasovEmil Bulatov
September 19, 2020

Targeted Transgenic Mice Using CRISPR /Cas9 Technology

Methods in Molecular Biology
Fatima El MarjouDenis Krndija
September 19, 2020

A robust and practical CRISPR/crRNA screening system for soybean cultivar editing using LbCpf1 ribonucleoproteins

Plant Cell Reports
Hyeran Kim, Jisun Choi
September 6, 2020
Open Access

PEG-Delivered CRISPR-Cas9 Ribonucleoproteins System for Gene-Editing Screening of Maize Protoplasts

Rodrigo Ribeiro Arnt Sant'AnaSarah Zanon Agapito-Tenfen
September 1, 2020
Open Access

Assessing Public Opinion on CRISPR-Cas9: Combining Crowdsourcing and Deep Learning

Journal of Medical Internet Research
Martin MüllerEffy Vayena
September 15, 2020

CRISPR-Cas-mediated gene editing in lactic acid bacteria

Molecular Biology Reports
Xin SongLian-Zhong Ai

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