DNA Supercoiling

DNA supercoiling is the over- or under-winding of a DNA strand. It is essential for several biological processes including DNA compacting, DNA metabolism, and likely gene expression. Here is the latest research.

January 21, 2022
Preprint
Open Access

Nucleosome topology and DNA sequence modulate the engagement of pioneer factors SOX2 and OCT4

BioRxiv : the Preprint Server for Biology
F. C. Malaga Gadea, Evgenia N. Nikolova
January 20, 2022
Preprint
Open Access

High abundance of transcription regulators compacts the nucleoid in Escherichia coli

BioRxiv : the Preprint Server for Biology
C. Yilmaz, Karin Schnetz
January 13, 2022

Two-Phase Dynamics of DNA Supercoiling based on DNA Polymer Physics.

Biophysical Journal
Biao Wan, Jin Yu
January 12, 2022
Open Access

Novel Tetrazole-Based Antimicrobial Agents Targeting Clinical Bacteria Strains: Exploring the Inhibition of Staphylococcus aureus DNA Topoisomerase IV and Gyrase.

International Journal of Molecular Sciences
Piotr RoszkowskiDaniel Szulczyk
January 11, 2022

Copper(II) and silver(I)-1,10-phenanthroline-5,6-dione complexes interact with double-stranded DNA: further evidence of their apparent multi-modal activity towards Pseudomonas aeruginosa.

Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry
Anna Clara Milesi GaldinoAndré Luis Souza Dos Santos
December 29, 2021
Preprint
Open Access

A spatial stochastic model reveals the role of supercoiling in transcription regulation

BioRxiv : the Preprint Server for Biology
Yuncong GengE. Roberts
December 25, 2021

DNA supercoiling-mediated collective behavior of co-transcribing RNA polymerases.

Nucleic Acids Research
Shubham TripathiHerbert Levine
December 23, 2021
Open Access

The bacterial promoter spacer modulates promoter strength and timing by length, TG-motifs and DNA supercoiling sensitivity.

Scientific Reports
Carlo A. KleinPatrick Sobetzko
December 23, 2021
Preprint
Open Access

DNA fluctuations reveal the size and dynamics of topological domains

BioRxiv : the Preprint Server for Biology
W. VanderlindenJ. Lipfert
December 4, 2021

DNA Supercoiling Drives a Transition between Collective Modes of Gene Synthesis.

Physical Review Letters
Purba ChatterjeeSangjin Kim
December 2, 2021
Open Access

Pyridine substituted BODIPYs: synthesis, characterization and cholinesterease, α-glucosidase inhibitory, DNA hydrolytic cleavage effects.

Turkish Journal of Chemistry
Burak BarutZekeriya Biyiklioğlu
November 30, 2021
Preprint
Open Access

Topoisomerases I and II facilitate condensin DC translocation to organize and repress X chromosomes in C. elegans

BioRxiv : the Preprint Server for Biology
A. K. MoraoSevinc Ercan
November 28, 2021
Open Access

Interaction of the Escherichia coli HU Protein with Various Topological Forms of DNA.

Biomolecules
Li HuangRoger McMacken
November 25, 2021
Preprint
Open Access

Collective polymerase dynamics emerge from DNA Supercoiling Mediated Transcription

BioRxiv : the Preprint Server for Biology
S. Sevier, Sahand Hormoz
November 12, 2021

Keeping intracellular DNA untangled: A new role for condensin?

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology
Joaquim RocaBelén Martínez-García
November 1, 2021

Nanomechanics of negatively supercoiled diaminopurine-substituted DNA.

Nucleic Acids Research
Domenico SalernoD. Dunlap

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