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DNA Supercoiling

DNA Supercoiling diagram by Aldona Griskeviciene, Shutterstock
Aldona Griskeviciene, Shutterstock

DNA supercoiling is the over- or under-winding of a DNA strand. It is essential for several biological processes including DNA compacting, DNA metabolism, and likely gene expression. Here is the latest research.

Top 20 most recent papers
Chemical Reviews

Single-Molecule Analysis and Engineering of DNA Motors

Chemical ReviewsOctober 30, 2019
Sonisilpa MohapatraTaekjip Ha
44
41
Advanced Materials

Advanced Actuator Materials Powered by Biomimetic Helical Fiber Topologies

Advanced MaterialsDecember 4, 2019
Geoffrey M Spinks
5
Journal of the American Chemical Society

DNA junction ligands trigger DNA damage and are synthetic lethal with DNA repair inhibitors in cancer cells

Journal of the American Chemical SocietyDecember 14, 2019
Katerina DuskovaDavid Monchaud
21
bioRxiv

BZIP Transcription Factors Modulate DNA Supercoiling Transitions

bioRxivDecember 13, 2019
Johanna Hörberg, Anna Reymer
3
bioRxiv

An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete

bioRxivNovember 21, 2019
Charles Vaughn SindelarMathieu Picardeau
9
Nature Communications

Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate

Nature CommunicationsJanuary 26, 2020
Stephen A McMahonTracey M Gloster
24
Scientific Reports

Acquisition of fluoroquinolone resistance leads to increased biofilm formation and pathogenicity in Campylobacter jejuni

Scientific ReportsDecember 5, 2019
Matthew V X WhelanTadhg Ó Cróinín
18
bioRxiv

Combining high-resolution AFM with MD simulations shows that DNA supercoiling induces kinks and defects that enhance flexibility and recognition.

bioRxivDecember 5, 2019
Alice L. B. PyneSarah A. Harris
23
bioRxiv

Interaction of two strongly divergent archaellins stabilizes the structure of the Halorubrum archaellum

bioRxivNovember 9, 2019
Mikhail G. PyatibratovOleg V. Fedorov
2
bioRxiv

Coarse-Grained Modeling of DNA Plectoneme Formation in the Presence of Base-Pair Mismatches

bioRxivDecember 21, 2019
Parth Rakesh DesaiKeir C. Neuman
6
Nature Communications

Chromatin fibers stabilize nucleosomes under torsional stress

Nature CommunicationsJanuary 9, 2020
Artur KaczmarczykNynke H Dekker
7
Nature Communications

The free energy landscape of retroviral integration

Nature CommunicationsOctober 20, 2019
Willem VanderlindenJan Lipfert
24
5
Physical Review Letters

Supercoiling in a Protein Increases its Stability

Physical Review LettersNovember 8, 2019
Szymon Niewieczerzał, Joanna I Sulkowska
Journal of Chromatography. a

Purification of supercoiled p53-encoding plasmid using an arginine-modified macroporous support

Journal of Chromatography. aJanuary 26, 2020
J F A ValenteF Sousa
Anti-cancer Agents in Medicinal Chemistry

Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics

Anti-cancer Agents in Medicinal ChemistryNovember 26, 2019
Yang LuA F M Motiur Rahman
1
Dalton Transactions : an International Journal of Inorganic Chemistry

Copper(ii) complexes with NNO ligands: synthesis, crystal structures, DNA cleavage, and anticancer activities

Dalton Transactions : an International Journal of Inorganic ChemistryDecember 4, 2019
Ping YangXiao-Bao Xie
1
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine-Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryOctober 30, 2019
Eman M Mohi El-DeenEman S Nossier
1
2
Journal of Inorganic Biochemistry

Structural basis and effect of copper(II) complexes with 4-oxo-thiazolidine ligands on DNA binding and nuclease activity

Journal of Inorganic BiochemistryNovember 27, 2019
Gloria AlzuetManuel Saa
The Journal of Physical Chemistry. B

Influence of Nucleoid-Associated Proteins on DNA Supercoiling

The Journal of Physical Chemistry. BNovember 12, 2019
Katelyn Dahlke, Charles E Sing
4
PloS One

Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint

PloS OneNovember 21, 2019
Rosevalentine BosireGábor Szabó
4
2

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