DNA Vaccine Delivery: Particulates

Biomaterial-based delivery systems based on micro- and nanoparticles that encapsulate plasmid DNA represent the most promising strategy for DNA vaccine delivery. Microparticulate delivery systems allow for passive targeting to antigen presenting cells through size exclusion and can allow for sustained presentation of DNA to cells through degradation and release of encapsulated vaccines. In contrast, nanoparticle encapsulation leads to increased internalization, overall greater transfection efficiency, and the ability to increase uptake across mucosal surfaces. Discover the latest research on DNA vaccine delivery here

July 28, 2020
Open Access

Characterization of Bacillus anthracis Spore Proteins Using a Nanoscaffold Vaccine Platform

Frontiers in Immunology
Dina R WeilhammerAmy Rasley
July 23, 2020
Preprint
Open Access

Oral delivery of SARS-CoV-2 DNA vaccines using attenuated Salmonella typhimurium as a carrier in rat

BioRxiv : the Preprint Server for Biology
Dezhi YangH. Baigude
July 14, 2020
Review

A review: Progress in the development of fish Vibrio spp. vaccines

Immunology Letters
Qianyu JiQing Liu
July 13, 2020

Resurrecting a p53 peptide activator - An enabling nanoengineering strategy for peptide therapeutics

Journal of Controlled Release : Official Journal of the Controlled Release Society
Wangxiao HeWuyuan Lu
July 17, 2020

A Novel Mucosal Adjuvant System for the Immunization Against Avian Coronavirus Causing Infectious Bronchitis

Journal of Virology
Shaswath S ChandrasekarAdel M Talaat
July 15, 2020
Open Access

SIV infection duration largely determines broadening of neutralizing antibody response in macaques

The Journal of Clinical Investigation
Fan WuVanessa M Hirsch
July 23, 2020

A novel formulation of Mtb72F DNA vaccine for immunization against tuberculosis

Iranian Journal of Basic Medical Sciences
Razieh DalirfardoueiMahboubeh Naderinasab
July 29, 2020
Review

What's New in Vaccine Science

Primary Care
Margot Savoy
July 23, 2020
Correction
Open Access

Erratum: Publisher Correction: New international guidance on quality, safety and efficacy of DNA vaccines

NPJ Vaccines
David W C Beasley
July 20, 2020

Advances in Development of mRNA-Based Therapeutics

Current Topics in Microbiology and Immunology
Lei HuangZhongmin Liu
July 11, 2020
Open Access

Acceptability of a hypothetical preventative HIV vaccine among people who use drugs in Vancouver, Canada

BMC Public Health
Taylor FlemingRyan McNeil
July 30, 2020
Review
Open Access

Impact of Heat Stress on Poultry Health and Performances, and Potential Mitigation Strategies

Animals : an Open Access Journal From MDPI
Sanjeev WastiBirendra Mishra
July 27, 2020

Effective inhibition of tumor in vivo with a novel DNA vaccine targeting chimeric G250

European Review for Medical and Pharmacological Sciences
T-R LiF-L Hui
July 15, 2020

Hollow Mesoporous Silica Nanoparticles with Extra-Large Mesopores for Enhanced Cancer Vaccine

ACS Applied Materials & Interfaces
Jun Yup LeeJaeyun Kim

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