DNA Vaccine Delivery: Particulates

Biomaterial-based delivery systems based on micro- and nanoparticles that encapsulate plasmid DNA represent the most promising strategy for DNA vaccine delivery. Microparticulate delivery systems allow for passive targeting to antigen presenting cells through size exclusion and can allow for sustained presentation of DNA to cells through degradation and release of encapsulated vaccines. In contrast, nanoparticle encapsulation leads to increased internalization, overall greater transfection efficiency, and the ability to increase uptake across mucosal surfaces. Discover the latest research on DNA vaccine delivery here

April 30, 2020
PreprintOpen Access

Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2

Bette KorberDavid Montefiori
May 22, 2020
Open Access

Robust antibody and cellular responses induced by DNA-only vaccination for HIV

JCI Insight
Stephen DeRosaM Juliana McElrath
May 3, 2020

CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection

The Journal of Immunology : Official Journal of the American Association of Immunologists
Althea CampuzanoChiung-Yu Hung
May 13, 2020
Open Access

Aluminum Nanoparticles Acting as a Pulmonary Vaccine Adjuvant-Delivery System (VADS) Able to Safely Elicit Robust Systemic and Mucosal Immunity

Journal of Inorganic and Organometallic Polymers and Materials
Ning WangTing Wang
May 5, 2020
Open Access

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

Tran Thi Nhu ThaoVolker Thiel
May 20, 2020
Open Access

Characterisation of alternative expression vectors for recombinant Bacillus Calmette-Guérin as live bacterial delivery systems

Memórias do Instituto Oswaldo Cruz
Larissa V NascimentoIvan P Nascimento
April 26, 2020

Screening for protective antigens of Cyprinid herpesvirus 2 and construction of DNA vaccines

Journal of Virological Methods
Xuemei YuanLi Liu
May 27, 2020
Open Access

DNA Vaccine Treatment in Dogs Experimentally Infected with Trypanosoma cruzi

Journal of Immunology Research
Minerva Arce-FonsecaOlivia Rodríguez-Morales
May 31, 2020

Pulmonary Delivery of Fenretinide: A Possible Adjuvant Treatment In COVID-19

International Journal of Molecular Sciences
Isabella OrientiGiovanna Farruggia
May 10, 2020
Open Access

Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination

The Journal of Immunology : Official Journal of the American Association of Immunologists
Lucille AdamFrédéric Martinon
April 30, 2020

Exosomes: From garbage bins to translational medicine

International Journal of Pharmaceutics
Ying LiuXiaoyu Li

Sign up to follow this feed and discover related papers.

Related Feeds


Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.


Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.


Anthrax toxin, comprising protective antigen, lethal factor, and oedema factor, is the major virulence factor of Bacillus anthracis, an agent that causes high mortality in humans and animals. Here is the latest research on Anthrax.

Anthrax Vaccines

Three different types of anthrax vaccines are available; a live-attenuated, an alum-precipitated cell-free filtrate and a protein recombinant vaccine. The effectiveness between the three is uncertain, but the live-attenuated have shown to reduce the risk of anthrax with low adverse events. Here is the latest research on anthrax vaccines.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Antianginal Drugs: Mechanisms of Action

Antianginal drugs, including nitrates, beta-blockers, and calcium channel blockers, are used in the treatment of angina pectoris. Here is the latest research on their use and their mechanism of action.

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.


An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

© 2020 Meta ULC. All rights reserved