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Down Syndrome

Down Syndrome diagram by Kateryna Kon, Shutterstock
Kateryna Kon, Shutterstock

Down syndrome is a chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe intellectual disability. Discover the latest research on Down syndrome here.

Top 20 most recent papers
May 22, 2020

Proteomic profiles of prevalent mild cognitive impairment and Alzheimer's disease among adults with Down syndrome

Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Melissa PetersenSid E O'Bryant
May 22, 2020

Amyloid accumulation in Down syndrome measured with amyloid load

Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Matthew D ZammitBradley T Christian
May 23, 2020

TET1 and 5-Hydroxymethylation Preserve the Stem Cell State of Mouse Trophoblast

Stem Cell Reports
Claire E SennerMyriam Hemberger
May 20, 2020
ReviewOpen Access

Neonatal Immune Incompatibilities between Newborn and Mother

Journal of Clinical Medicine
Borros Arneth
May 24, 2020

The effect of exercise on cardiometabolic risk factors in adults with chronic spinal cord injury: A systematic review

Archives of Physical Medicine and Rehabilitation
Matthew FarrowJames Bilzon
May 21, 2020

Postintravenous immunoglobulin stroke in a toddler with Down syndrome: a diagnostic challenge

BMJ Case Reports
Teck-Hock TohHussain Imam Mohd Ismail
May 20, 2020
ReviewOpen Access

Effects of Antiplatelet and Nonsteroidal Anti-inflammatory Medications on Platelet-Rich Plasma: A Systematic Review

Orthopaedic Journal of Sports Medicine
Christopher FreyPrathap Jayaram
May 13, 2020

Bite Force and Occlusal Patterns in the Mixed Dentition of Children with Down Syndrome

Journal of Prosthodontics : Official Journal of the American College of Prosthodontists
Mansour K AsseryMClin Dent
May 26, 2020

Nutritional challenges in children and adolescents with Down syndrome

The Lancet Child & Adolescent Health
Marianne NordstrømSvein Olav Kolset
May 24, 2020

Children with Down syndrome can benefit from language interventions; Results from a systematic review and meta-analysis

Journal of Communication Disorders
Elizabeth SmithKari-Anne B Næss
May 22, 2020

First-trimester screening for trisomy 21 via an individualized nomogram

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
Y SunQ Wu
May 23, 2020

Tracheotomy in COVID-19 patients: Optimizing patient selection and identifying prognostic indicators

Head & Neck
Thomas J StubingtonMohammed S Mansuri
May 22, 2020

Down syndrome: Distribution of brain amyloid in mild cognitive impairment

Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
David B KeatorIra T Lott
May 24, 2020

Are patients with Down syndrome vulnerable to life-threatening COVID-19?

Acta neurologica Belgica
Harald De Cauwer, Ann Spaepen
May 15, 2020
ReviewOpen Access

Effectiveness of therapeutic footwear for children: A systematic review

Journal of Foot and Ankle Research
Matthew HillNachiappan Chockalingam
May 26, 2020

The Role of Diet and Nutrition in Migraine Triggers and Treatment: A Systematic Literature Review

Nada Ahmad HindiyehSheena K Aurora

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