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Dravet Syndrome

Dravet Syndrome diagram by undefined

Dravet syndrome, previously known as severe myoclonic epilepsy of infancy (SMEI), is a rare, catastrophic, lifelong form of epilepsy with frequent and/or prolonged seizures that are often triggered by hot temperatures or fever. Discover the latest research on Dravet syndrome here.

Top 20 most recent papers
bioRxiv

Phenotype-based screening of synthetic cannabinoids in a Dravet Syndrome zebrafish model

bioRxivOctober 23, 2019
Aliesha L GriffinScott C. Baraban
16
bioRxiv

Defective excitatory/inhibitory synapse balance and increased neuron apoptosis in a zebrafish model of Dravet syndrome

bioRxivSeptember 28, 2019
Alexandre BrenetNadia Soussi-Yanicostas
7
Scientific Reports

Epilepsy and neuropsychiatric comorbidities in mice carrying a recurrent Dravet syndrome SCN1A missense mutation

Scientific ReportsOctober 2, 2019
Ana RicobarazaRuben Hernandez-Alcoceba
15
1
8
JAMA Neurology

Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens: A Randomized Clinical Trial

JAMA NeurologyDecember 2, 2019
Rima NabboutFAiRE, DS Study Group
42
11
1
Annals of Neurology

SCN1A variants in vaccine-related febrile seizures: a prospective study

Annals of NeurologyNovember 22, 2019
John A DamianoSamuel Frank Berkovic
2
1
CNS Drugs

Recent Advances in the Drug Treatment of Dravet Syndrome

CNS DrugsSeptember 23, 2019
Elaine C Wirrell, Rima Nabbout
1
6
bioRxiv

Early hippocampal hyperexcitability followed by disinhibition in a mouse model of Dravet syndrome

bioRxivOctober 2, 2019
Yael AlmogMoran Rubinstein
20
3
bioRxiv

Home-cage Monitoring Ascertains Signatures of Ictal and Interictal Behavior In Mouse Models of Generalized Seizures

bioRxivAugust 20, 2019
Miranda J JankovicVaishnav Krishnan
2
Drugs

Drug Development for Rare Paediatric Epilepsies: Current State and Future Directions

DrugsNovember 18, 2019
Stéphane AuvinJ Helen Cross
8
bioRxiv

Deletion of a non-canonical promoter regulatory element causes loss of Scn1a expression and epileptic phenotypes in mice

bioRxivSeptember 12, 2019
Jessica L HaighAlex S Nord
10
3
Neurology

Dravet syndrome and parkinsonism: A case report investigating the dopaminergic system

NeurologyAugust 23, 2019
Lisa M DeuelDrew S Kern
4
1
Molecular Therapy : the Journal of the American Society of Gene Therapy

dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice

Molecular Therapy : the Journal of the American Society of Gene TherapySeptember 3, 2019
Gaia ColasanteVania Broccoli
34
16
1
European Journal of Medicinal Chemistry

Polygala tenuifolia-Acori tatarinowii herbal pair as an inspiration for substituted cinnamic α-asaronol esters: Design, synthesis, anticonvulsant activity, and inhibition of lactate dehydrogenase study

European Journal of Medicinal ChemistrySeptember 21, 2019
Ya-Jun BaiXiao-Hui Zheng
Brain : a Journal of Neurology

Synaptic clustering differences due to different GABRB3 mutations cause variable epilepsy syndromes

Brain : a Journal of NeurologyAugust 23, 2019
Yi-Wu ShiJing-Qiong Kang
12
1
4
Anesthesia Progress

Anesthetic Management of Patient With Dravet Syndrome: A Case Report

Anesthesia ProgressJanuary 1, 2019
Naohiro OhshitaYoshihiro Momota
1
2
1
Human Mutation

SCN1A variants from bench to bedside-improved clinical prediction from functional characterization

Human MutationNovember 28, 2019
Andreas BrunklausSameer M Zuberi
Pediatric Neurology

Positron Emission Tomography in Pediatric Neurodegenerative Disorders

Pediatric NeurologyJuly 17, 2019
Harry T Chugani
2
7
PloS One

Home-cage monitoring ascertains signatures of ictal and interictal behavior in mouse models of generalized seizures

PloS OneNovember 7, 2019
Miranda J JankovicVaishnav Krishnan
Neuropediatrics

Accuracy of Flash Glucose Monitoring in a Patient with Dravet Syndrome on a Ketogenic Diet

NeuropediatricsSeptember 17, 2019
Aline KortasMarkus Rauchenzauner
European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society

Gait abnormalities in people with Dravet syndrome: A cross-sectional multi-center study

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology SocietyOctober 5, 2019
Roberto Di MarcoAlessandra Del Felice

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