Drug Efflux Transporters

Drug efflux transporters, such as P-glycoprotein (Pgp), multidrug resistance proteins (MRPs) or organic anion transporting polypeptides (OATPs), transport drug molecules out of the cells. Discover the latest research on drug efflux transporters here.

September 19, 2021

Synthesis and biological assessment of new pyrimidopyrimidines as inhibitors of breast cancer resistance protein (ABCG2).

Bioorganic Chemistry
Imen DakhlaouiLhassane Ismaili
September 18, 2021

Polybrominated diphenyl ethers BDE-47 and BDE-99 modulate murine melanoma cell phenotype in vitro.

Environmental Science and Pollution Research International
Gisleine Jarenko SteilFrancisco Filipak Neto
September 18, 2021

Reversing Multidrug Resistance by Inducing Mitochondrial Dysfunction for Enhanced Chemo-Photodynamic Therapy in Tumor.

ACS Applied Materials & Interfaces
Chao ShiXiaojun Peng
September 17, 2021
Open Access

Multimodal Detection of Dopamine by Sniffer Cells Expressing Genetically Encoded Fluorescence Sensors

BioRxiv : the Preprint Server for Biology
C. K. HerenbrinkFreja Herborg
September 17, 2021

Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.

ACS Medicinal Chemistry Letters
Joshi M RamanjuluRobert W Marquis
September 17, 2021

Transmembrane H+ fluxes and the regulation of neural induction in Xenopus laevis.

Zygote : the Biology of Gametes and Early Embryos
Ho Chi LeungSarah E Webb
September 16, 2021
Open Access

The copper resistome of group B Streptococcus reveals insight into the genetic basis of cellular survival during metal ion stress

BioRxiv : the Preprint Server for Biology
K. G. GohGlen C Ulett
September 16, 2021

Protective effect of Lactobacillus reuteri Lb11 from chicken intestinal tract against Salmonella Enteritidis SE05 in vitro.

Antonie van Leeuwenhoek
Dan Hai, Xianqing Huang
September 16, 2021
Open Access

Uptake of Aβ by OATPs might be a new pathophysiological mechanism of Alzheimer disease.

BMC Neuroscience
Jinhua WenPu Li
September 15, 2021
Open Access

Heterodimers of functionally divergent ARF-GEF paralogues prevented by self-interacting dimerisation domain

BioRxiv : the Preprint Server for Biology
G. JürgensS. Takada
September 15, 2021

Regulation of Cell Volume by Nanosecond Pulsed Electric Fields.

The Journal of Physical Chemistry. B
Qi YangTakakazu Nakabayashi

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