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Drug-Inactivating Enzymes & Resistance

Drug-Inactivating Enzymes & Resistance diagram by Swaminathan et al, Wikimedia
Swaminathan et al, Wikimedia

Drug inactivation or modification is one of the mechanisms through which resistance occurs. For instance, some penicillin-resistant bacteria produce beta-lactamases to enzymatically deactivate Penicillin G. Here is the latest research on drug inactivating enzymes and resistance.

Top 20 most recent papers
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

MET Alterations are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchFebruary 23, 2020
Ibiayi Dagogo-JackAaron N Hata
25
Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy

The third national Japanese antimicrobial susceptibility pattern surveillance program: Bacterial isolates from complicated urinary tract infection patients

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of ChemotherapyFebruary 22, 2020
Kanao KobayashiShuntaro Koda
1
Cell Biology and Toxicology

Glutathione S-transferase P influences the Nrf2-dependent response of cellular thiols to seleno-compounds

Cell Biology and ToxicologyFebruary 20, 2020
Desirée BartoliniFrancesco Galli
Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy

Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors

Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer ChemotherapyFebruary 23, 2020
Sabrina DallavalleRoberta Fruttero
Expert Opinion on Therapeutic Targets

Emerging therapeutic targets for neuromyelitis optica spectrum disorders

Expert Opinion on Therapeutic TargetsFebruary 20, 2020
Lukmanee TradtrantipAlan S Verkman
International Journal of Medical Microbiology : IJMM

Complete genome sequence and genome-scale metabolic modelling of Acinetobacter baumannii type strain ATCC 19606

International Journal of Medical Microbiology : IJMMFebruary 22, 2020
Yan ZhuJian Li
2
bioRxiv

Automated continuous evolution of proteins in vivo

bioRxivFebruary 22, 2020
Ziwei ZhongChang C Liu
76
International Journal of Environmental Research and Public Health

Molecular Diversity of ESBL-Producing Escherichia coli from Foods of Animal Origin and Human Patients

International Journal of Environmental Research and Public HealthFebruary 23, 2020
Ángel AlegríaJesús A Santos

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