Drug Resistant Epilepsy

Drug-resistant epilepsy, also known as refractory or pharmacoresistant epilepsy, is defined as failure of adequate trials of two appropriate and tolerated antiepileptic drugs (as monotherapies or in combination) to achieve sustained seizure freedom. Discover the latest research on drug-resistant epilepsy here.

January 16, 2021

Fast oscillations >40 Hz localize the epileptogenic zone: An electrical source imaging study using high-density electroencephalography

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Tamir AvigdorBirgit Frauscher
January 15, 2021

Ethical examination of deep brain stimulation's 'last resort' status

Journal of Medical Ethics
Ian Stevens, Frederic Gilbert
January 20, 2021

Preictal state detection using prodromal symptoms: A machine learning approach

Louis CousynMario Chavez
January 14, 2021
Open Access

Focused Ultrasound in Neuroscience. State of the Art and Future Perspectives

Brain Sciences
Giuseppe Roberto GiammalvaRosario Maugeri
January 19, 2021

Lateralization value of peri-ictal headache in drug-resistant focal epilepsy

Epilepsy & Behavior : E&B
Mohamed AlKhajaTariq Abalkhail
January 19, 2021

GATOR1-related focal cortical dysplasia in epilepsy surgery patients and their families: A possible gradient in severity?

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
Barbora BenovaPavel Krsek
January 13, 2021

Gabapentin add-on treatment for drug-resistant focal epilepsy

The Cochrane Database of Systematic Reviews
Mariangela PanebiancoAnthony G Marson
January 17, 2021

Personality changes in patients with refractory epilepsy after surgical treatment: A systematic review

Seizure : the Journal of the British Epilepsy Association
Elena IurinaLuis Pintor
January 16, 2021

Electroencephalography complexity in infantile spasms and its association with treatment response

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Yen-Ju ChuWang-Tso Lee
January 13, 2021

Impact of drug-resistant epilepsy on sleep in children: How do they behave?

Epilepsy & Behavior : E&B
Prateek Kumar Panda, Indar Kumar Sharawat
January 14, 2021
Open Access

Clinical manifestations and epilepsy treatment in Japanese patients with pathogenic CDKL5 variants

Brain & Development
Yu KobayashiNaomichi Matsumoto
January 19, 2021

Histological assessment of a chronically implanted cylindrically-shaped, polymer-based neural probe in the monkey

Journal of Neural Engineering
Marzio GerbellaLuca Bonini
January 13, 2021

Reply to "Impact of drug-resistant epilepsy on sleep in children: How they behave?"

Epilepsy & Behavior : E&B
Ebru ArhanAyşe Serdaroglu
January 13, 2021
Open Access

A Case of Lafora Disease Diagnosed by Axillary Skin Biopsy

Türk patoloji dergisi
Elife KimiloĞluÇağla Turan
January 19, 2021

A critical evaluation of fenfluramine hydrochloride for the treatment of Dravet syndrome

Expert Review of Neurotherapeutics
An-Sofie Schoonjans, Berten Ceulemans

Sign up to follow this feed and discover related papers.

Related Feeds

Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.

Angelman Syndrome

Angelman syndrome is a neurogenetic imprinting disorder caused by loss of the maternally inherited UBE3A gene and is characterized by generalized epilepsy, limited expressive speech, sleep dysfunction, and movement disorders. Here is the latest research.

Benign Rolandic Epilepsy

Benign Rolandic epilepsy is a partial idiopathic epilepsy of childhood presenting with a nocturnal seizure and with a typical EEG showing centrotemporal spike and multifocal or generalized sharp slow waves. Here is the latest research.

Dravet Syndrome

Dravet syndrome, previously known as severe myoclonic epilepsy of infancy (SMEI), is a rare, catastrophic, lifelong form of epilepsy with frequent and/or prolonged seizures that are often triggered by hot temperatures or fever. Discover the latest research on Dravet syndrome here.

Early Myoclonic Encephalopathy

Early myoclonic encephalopathy is an epileptic syndrome typically diagnosed by three months of age. It is characterized by frequent seizures and severe early encephalopathy and has a severely reduced life expectancy. Causes can include metabolic abnormalities or genetic mutations. Find the latest research on early myoclonic encephalopathy here.


Epilepsy is a chronic neurological disorder characterized by unprovoked and recurrent seizures. Discover the latest research on factors and mechanisms that underlie epilepsy here.

Frontal Lobe Epilepsy

Frontal lobe epilepsy is characterized by brief, recurring seizures, often during sleep. Depending on the areas of the brain that are affected, these seizures may be asymptomatic or present with motor or verbal symptoms. Find the latest research on frontal lobe epilepsy here.

Juvenile Myoclonic Epilepsy

Juvenile myoclonic epilepsy, previously known as idiopathic generalized epilepsy, is a form of generalized epilepsy whose cause is presumed to be genetic in origin. The first seizure typically occurs between the ages of 5-12, and symptoms may improve after the fourth decade of life. Seizure may be of different subtypes, including absence, myoclonic, and tonic-clonic. Find the latest research on juvenile myoclinic epilepsy here.

Lafora Disease

Lafora disease is an inherited neurodegenerative disorder characterized by the presence of abnormal glycogen inclusions, called Lafora bodies, in neurons and other tissues. Here is the latest research on this fatal autosomal recessive disorder.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

© 2021 Meta ULC. All rights reserved