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Efflux-Mediated Drug Resistance

Efflux-Mediated Drug Resistance diagram by Alila Medical Media, Shutterstock
Alila Medical Media, Shutterstock

Efflux-mediated drug resistance is one mechanism where bacteria can express proteins that pump out antibiotics, thereby rendering therapy ineffective. Discover the latest research on efflux-mediated drug resistance here.

Top 20 most recent papers

Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent

DrugsJanuary 24, 2020
George G ZhanelJames A Karlowsky
ACS Infectious Diseases

Drug permeation against efflux by two transporters

ACS Infectious DiseasesFebruary 11, 2020
Paramita SahaValentin V Rybenkov
Expert Review of Anti-infective Therapy

Mechanisms of antimicrobial resistance in Stenotrophomonas maltophilia : a review of current knowledge

Expert Review of Anti-infective TherapyFebruary 14, 2020
Teresa Gil-GilPaula Blanco
Chemistry : a European Journal

Doxorubicin Encapsulated in P-glycoprotein-Modified 2D-Nanodisks Overcomes Multidrug Resistance

Chemistry : a European JournalJanuary 9, 2020
Tingting JiangRui Guo
International Journal of Molecular Sciences

Molecular Interactions of Carbapenem Antibiotics with the Multidrug Efflux Transporter AcrB of Escherichia coli

International Journal of Molecular SciencesFebruary 5, 2020
Alessio AtzoriPaolo Ruggerone
Antimicrobial Resistance and Infection Control

Molecular surveillance of carbapenemase-producing Pseudomonas aeruginosa at three medical centres in Cologne, Germany

Antimicrobial Resistance and Infection ControlJanuary 2, 2020
Elena SchäferAndreas F Wendel
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Identifying Ortholog Selective Fragment Molecules for Bacterial Glutaredoxins by NMR and Affinity Enhancement by Modification with an Acrylamide Warhead

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryJanuary 8, 2020
Ram B KhattriThomas C Leeper
Drug Design, Development and Therapy

Levonadifloxacin, a Novel Broad-Spectrum Anti-MRSA Benzoquinolizine Quinolone Agent: Review of Current Evidence

Drug Design, Development and TherapyJanuary 11, 2020
Sachin S BhagwatMahesh Patel

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