EGFR In Non-Small Cell Lung Carcinoma

Around 10-35% of non-small cell lung carcinomas have drug-sensitizing mutations in the epidermal growth factor receptor (EGFR) gene. In these cases, tyrosine kinase inhibitor therapy is recommended. Find the latest research on EGFR and non-small cell lung carcinoma here.

September 10, 2020
Case Report
Open Access

KIF5B -EGFR Fusion: A Novel EGFR Mutation in Lung Adenocarcinoma

OncoTargets and Therapy
Hui Xu, Chuan Shao
September 16, 2020
Open Access

Afatinib for the first-line treatment of EGFR mutation-positive NSCLC in China: a review of clinical data

Future Oncology
Hai-Yan Tu, Yi-Long Wu
September 19, 2020

PLCγ1‑dependent invasion and migration of cells expressing NSCLC‑associated EGFR mutants

International Journal of Oncology
Sonam MittalMaitreyi S Rajala
September 15, 2020

Real-world evaluation of factors for interstitial lung disease incidence and radiologic characteristics in patients with epidermal growth factor receptor T790M-positive non-small cell lung cancer treated with osimertinib in Japan

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer
Akihiko GemmaYuichiro Ohe
September 19, 2020

CH7233163 overcomes osimertinib resistant EGFR-Del19/T790M/C797S mutation

Molecular Cancer Therapeutics
Kenji KashimaHiroshi Sakamoto
September 16, 2020
Open Access

Correlation of epidermal growth factor receptor mutation status in plasma and tissue samples of patients with non-small cell lung cancer

Journal of Cancer Research and Therapeutics
Mee-Sook RohChoonhee Son
September 12, 2020
Open Access

Toxicity with small molecule and immunotherapy combinations in non-small cell lung cancer

Cancer Immunology, Immunotherapy : CII
H AdderleyC R Lindsay
September 16, 2020
Case Report
Open Access

Successful treatment of nonsmall cell lung cancer patients with leptomeningeal metastases using whole brain radiotherapy and tyrosine kinase inhibitors

Journal of Cancer Research and Therapeutics
Masakuni SakaguchiTsutomu Saito
September 20, 2020

Design, synthesis and biological evaluation of novel heptamethine cyanine dye-erlotinib conjugates as antitumor agents

Bioorganic & Medicinal Chemistry Letters
Xiaoguang YangChun Guo
September 19, 2020

DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR

Cell Death & Disease
Ji GengZheng-Hong Qin

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