Endolysosomal System in Neurons

Endosomal-lysosomal processes are essential for degradation of unusable cellular material. Disruptions in these processes are associated with neurodegenerative disorders. Here is the latest research.

December 29, 2020

A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization

Experimental Cell Research
Khalisah L ZulkefliPaul A Gleeson
November 14, 2020
Review
Open Access

The return of malonyl-CoA to the brain: Cognition and other stories

Progress in Lipid Research
Rut FadóNúria Casals
January 9, 2021
Open Access

Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol

Acta Neuropathologica
Juan Carlos PolancoJürgen Götz
December 15, 2020
Open Access

NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

Developmental Cell
Oliver B DavisRoberto Zoncu
January 9, 2021
Open Access

Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro

Fluids and Barriers of the CNS
Snehal RautAbraham Al-Ahmad
December 20, 2020
Preprint
Open Access

Apoptosis is a generator of Wnt-dependent regeneration and homeostatic cell renewal in the ascidian Ciona

BioRxiv : the Preprint Server for Biology
William R. Jeffery, S. Goricki
January 11, 2021
Preprint
Open Access

Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit

BioRxiv : the Preprint Server for Biology
X. L. H. YongVictor Anggono
December 18, 2020
Review
Open Access

When Friendship Turns Sour: Effective Communication Between Mitochondria and Intracellular Organelles in Parkinson's Disease

Frontiers in Cell and Developmental Biology
Tsu-Kung LinTzu-Jou Wang
January 2, 2021
Review
Open Access

Lipid Transfer-Dependent Endosome Maturation Mediated by Protrudin and PDZD8 in Neurons

Frontiers in Cell and Developmental Biology
Michiko Shirane
December 21, 2020
Review
Open Access

Walking the line: mechanisms underlying directional mRNA transport and localisation in neurons and beyond

Cellular and Molecular Life Sciences : CMLS
Reem Abouward, Giampietro Schiavo
January 1, 2021
Review
Open Access

The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson's Disease

Frontiers in Cell and Developmental Biology
Georgia MinakakiLena F Burbulla
December 30, 2020
Review
Open Access

The axonal endo-lysosomal and autophagic systems

Journal of Neurochemistry
Marijn KuijpersTolga Soykan
January 11, 2021

Is SGSH heterozygosity a risk factor for early-onset neurodegenerative disease?

Journal of Inherited Metabolic Disease
Meghan L DouglassKim M Hemsley
January 8, 2021
Open Access

Delivery of single-domain antibodies into neurons using a chimeric toxin-based platform is therapeutic in mouse models of botulism

Science Translational Medicine
Shin-Ichiro MiyashitaMin Dong
December 20, 2020
Open Access

The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour

Cellular and Molecular Life Sciences : CMLS
Enrico CastroflorioPeter L Oliver
January 4, 2021
Preprint
Open Access

Multiscale Analysis of the Amyloid Degradation Toxicity Hypothesis of Alzheimer’s Disease

Preprints.org
Dmitry Zaretsky, Maria Zaretskaia
January 3, 2021
Review

Physiological and pathological functions of TMEM106B: a gene associated with brain aging and multiple brain disorders

Acta Neuropathologica
Tuancheng FengFenghua Hu

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