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Enhancer Activation & Histones (Keystone)

Enhancer Activation & Histones (Keystone) diagram by undefined

Enhancers are short regions of the DNA which can be bound by activator or repressor proteins to affect transcription of a particular gene. Here is the latest research on mechanisms of enhancer activation using the histone variant H3.

Top 20 most recent papers
bioRxiv

PHYTOCHROME INTERACTING FACTORs trigger environmentally responsive chromatin dynamics

bioRxivNovember 1, 2019
Björn C. WilligeJoanne Chory
35
bioRxiv

Varying co-factor requirements for MAML1-dependent transcription at different Notch-responsive target genes

bioRxivJanuary 14, 2020
Julia M RogersStephen Blacklow
1
bioRxiv

Histone chaperone Nucleophosmin regulates transcription of key genes involved in oral tumorigenesis.

bioRxivNovember 22, 2019
Parijat SenapatiTapas K Kundu
6
bioRxiv

The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate

bioRxivDecember 27, 2019
David FordAndrew Dingwall
8
bioRxiv

Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer's Disease

bioRxivNovember 7, 2019
How-Wing LeungAntonius M VanDongen
5
2
bioRxiv

Nuclear GAPDH signaling mediates pathological cardiac hypertrophy

bioRxivNovember 16, 2019
Manling ZhangEiki Takimoto
4
International Journal of Biological Sciences

Transforming growth factor beta (TGF-β) is activated by the CtBP2-p300-AP1 transcriptional complex in chronic renal failure

International Journal of Biological SciencesJanuary 14, 2020
Ping ZhouAimin Zhong
Journal of Autoimmunity

EZH2 deficiency attenuates Treg differentiation in rheumatoid arthritis

Journal of AutoimmunityJanuary 19, 2020
Xin-Yue XiaoXuan Zhang
1
JCI Insight

Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1-dependent mechanism

JCI InsightSeptember 20, 2019
Malik HamaidiaLuc Willems
5
5
BMC Cancer

Ubiquitous expressed transcript promotes tumorigenesis by acting as a positive modulator of the polycomb repressive complex 2 in clear cell renal cell carcinoma

BMC CancerSeptember 5, 2019
Jin ZengZhiqiang Chen
bioRxiv

Phosphorylated Lamin A targets active enhancers and is associated with abnormal transcriptional activation in progeria

bioRxivJune 26, 2019
Kohta IkegamiIvan P. Moskowitz
5
3
EMBO Molecular Medicine

Nuclear receptor corepressor 1 represses cardiac hypertrophy

EMBO Molecular MedicineSeptember 19, 2019
Chao LiSheng-Zhong Duan
2
2
International Journal of Molecular Sciences

Inhibition of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Hampers the Vasopressin-dependent Stimulation of Myogenic Differentiation

International Journal of Molecular SciencesAugust 30, 2019
Silvia SorrentinoBianca Maria Scicchitano
3
5
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research

EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral ResearchSeptember 6, 2019
Juraj AdamikDeborah L Galson
3
1
Cell Reports

Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis

Cell ReportsNovember 7, 2019
Yi ZengYan Wang
20
5
International Immunopharmacology

Novel pharmacological inhibition of EZH2 attenuates septic shock by altering innate inflammatory responses to sepsis

International ImmunopharmacologySeptember 14, 2019
Qianqian ZhangLunxian Tang
Oncology Letters

Clinical significance of enhancer of zeste homolog 2 and histone deacetylases 1 and 2 expression in peripheral T-cell lymphoma

Oncology LettersAugust 20, 2019
Huilai ZhangXianhuo Wang
2
3
Oncogenesis

A Ras-LSD1 axis activates PI3K signaling through PIK3IP1 suppression

OncogenesisJanuary 5, 2020
Kyunghee LeeSang Hyun Lee
Trends in Genetics : TIG

The Bivalent Genome: Characterization, Structure, and Regulation

Trends in Genetics : TIGDecember 11, 2019
Enrique BlancoLuciano Di Croce
76
Oncology Reports

Growth inhibition and transcriptional effects of ribavirin in lymphoma

Oncology ReportsJuly 20, 2019
Guadalupe Dominguez-GomezAlfonso Dueñas-Gonzalez
4
1

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