Feed Preview

Fast Growing

Enhancer Activation & Histones (Keystone)

Enhancer Activation & Histones (Keystone) diagram by undefined

Enhancers are short regions of the DNA which can be bound by activator or repressor proteins to affect transcription of a particular gene. Here is the latest research on mechanisms of enhancer activation using the histone variant H3.

Top 20 most recent papers

PHYTOCHROME INTERACTING FACTORs trigger environmentally responsive chromatin dynamics

bioRxivNovember 1, 2019
Björn C. WilligeJoanne Chory

Varying co-factor requirements for MAML1-dependent transcription at different Notch-responsive target genes

bioRxivJanuary 14, 2020
Julia M RogersStephen Blacklow

Histone chaperone Nucleophosmin regulates transcription of key genes involved in oral tumorigenesis.

bioRxivNovember 22, 2019
Parijat SenapatiTapas K Kundu

The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate

bioRxivDecember 27, 2019
David FordAndrew Dingwall

Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer's Disease

bioRxivNovember 7, 2019
How-Wing LeungAntonius M VanDongen

Nuclear GAPDH signaling mediates pathological cardiac hypertrophy

bioRxivNovember 16, 2019
Manling ZhangEiki Takimoto
International Journal of Biological Sciences

Transforming growth factor beta (TGF-β) is activated by the CtBP2-p300-AP1 transcriptional complex in chronic renal failure

International Journal of Biological SciencesJanuary 14, 2020
Ping ZhouAimin Zhong
Journal of Autoimmunity

EZH2 deficiency attenuates Treg differentiation in rheumatoid arthritis

Journal of AutoimmunityJanuary 19, 2020
Xin-Yue XiaoXuan Zhang
JCI Insight

Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1-dependent mechanism

JCI InsightSeptember 20, 2019
Malik HamaidiaLuc Willems
BMC Cancer

Ubiquitous expressed transcript promotes tumorigenesis by acting as a positive modulator of the polycomb repressive complex 2 in clear cell renal cell carcinoma

BMC CancerSeptember 5, 2019
Jin ZengZhiqiang Chen

Phosphorylated Lamin A targets active enhancers and is associated with abnormal transcriptional activation in progeria

bioRxivJune 26, 2019
Kohta IkegamiIvan P. Moskowitz
EMBO Molecular Medicine

Nuclear receptor corepressor 1 represses cardiac hypertrophy

EMBO Molecular MedicineSeptember 19, 2019
Chao LiSheng-Zhong Duan
International Journal of Molecular Sciences

Inhibition of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Hampers the Vasopressin-dependent Stimulation of Myogenic Differentiation

International Journal of Molecular SciencesAugust 30, 2019
Silvia SorrentinoBianca Maria Scicchitano
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research

EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral ResearchSeptember 6, 2019
Juraj AdamikDeborah L Galson
Cell Reports

Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis

Cell ReportsNovember 7, 2019
Yi ZengYan Wang
International Immunopharmacology

Novel pharmacological inhibition of EZH2 attenuates septic shock by altering innate inflammatory responses to sepsis

International ImmunopharmacologySeptember 14, 2019
Qianqian ZhangLunxian Tang
Oncology Letters

Clinical significance of enhancer of zeste homolog 2 and histone deacetylases 1 and 2 expression in peripheral T-cell lymphoma

Oncology LettersAugust 20, 2019
Huilai ZhangXianhuo Wang

A Ras-LSD1 axis activates PI3K signaling through PIK3IP1 suppression

OncogenesisJanuary 5, 2020
Kyunghee LeeSang Hyun Lee
Trends in Genetics : TIG

The Bivalent Genome: Characterization, Structure, and Regulation

Trends in Genetics : TIGDecember 11, 2019
Enrique BlancoLuciano Di Croce
Oncology Reports

Growth inhibition and transcriptional effects of ribavirin in lymphoma

Oncology ReportsJuly 20, 2019
Guadalupe Dominguez-GomezAlfonso Dueñas-Gonzalez

See more papers from this feed

Related Feeds

Aging Genetics (Keystone)

This feed focuses on aging epidemiology and genetic, epigenetic, and proteomic aspects underlying aging, as well as aging- associated biomarkers. Here the latest research in this domain.

Bivalency & Gene Expression (Keystone)

Bivalent chromatin are segments of DNA, bound to histone proteins, that have both repressing and activating epigenetic regulators in the same region. Here is the latest research on bivalent chromatin and gene expression.

Cell Aging (Keystone)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Cell Signaling & Cancer Epigenetics (Keystone)

Epigenetic changes are present and dysregulated in many cancers, including DNA methylation, non-coding RNA segments and post-translational protein modifications. This feed covers the latest research on signaling and epigenetics in cell growth and cancer.

ChIP-Seq (Keystone)

Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a genome-wide technique used to map histone marks and protein binding (i.e. transcription factors) on chromatin. This can reveal insight into the regulation and dynamics of gene expression. Discover the latest research on ChIP-seq here.

Chromatin Regulation and Circadian Clocks (Keystone)

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on chromatin regulation and circadian clocks here.

Chromatin Regulators: Differentiation (Keystone)

Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins in cellular differentiation.

Chromatin Remodeling (Keystone)

Chromatin remodeling is essential for regulation of gene expression, DNA replication, as well as DNA repair. Here is the latest research on chromatin remodeling complexes and mechanisms underlying this process.

Cryogenic Electron Microscopy (Keystone)

Cryogenic electron microscopy (Cryo-EM) uses a specific technique to allow for the visualization of macromolecules and their assemblies at a near-atomic resolution. Discover the latest research on Cryo-EM here.

DNA Methylation (Keystone)

DNA methylation is an epigenetic mechanism of gene regulation, and dysregulation of DNA methylation has been associated with tumorigenesis. Discover the latest research on DNA methylation here.

© 2020 Meta ULC. All rights reserved