Epigenetic Changes in Pain

Targeted epigenetic interventions provide the tools to prevent nociceptive sensitization, mood-related symptoms, and other adaptations that occur in response to injury or inflammation, which will facilitate pain management and improve treatment efficacy in many chronic pain conditions. Here is the latest research on the epigenetics changes in pain.

October 18, 2021
Open Access

Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NFκB to promote axonal regeneration and remyelination.

Journal of Neuroinflammation
Anjali YadavChia-Ching Wu
October 13, 2021
Review
Open Access

Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature).

International Journal of Molecular Sciences
Beata SmolarzHanna Romanowicz
October 8, 2021
Review

Implications on hypnotherapy: Neuroplasticity, epigenetics and pain.

Neuroscience and Biobehavioral Reviews
N CsászárI Bókkon
October 7, 2021
Comment / Editorial

A step towards understanding disparities: linking race, ancestry, epigenetics and pain.

Epigenomics
Vidya Chidambaran, Tesfaye B Mersha
October 6, 2021

Targeting the toll-like receptor pathway as a therapeutic strategy for neonatal infection.

American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Maria L DiasFiona Brigid McDonald
October 3, 2021
Review

How does hip osteoarthritis differ from knee osteoarthritis?

Osteoarthritis and Cartilage
M HallK L Bennell
September 27, 2021
Review

Histone post-translational modifications as potential therapeutic targets for pain management.

Trends in Pharmacological Sciences
Jose V Torres-PerezIstvan Nagy
September 25, 2021

The epigenetic mechanisms involved in chronic pain in rodents: A mini-review.

Current Neuropharmacology
Ting XuWen-Jun Xin
September 22, 2021

Dual BET/HDAC inhibition to relieve neuropathic pain: Recent advances, perspectives, and future opportunities.

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Maria Novella RomanelliNicoletta Galeotti
September 22, 2021

Genome-Wide Epigenomic Analyses in Patients With Nociceptive and Neuropathic Chronic Pain Subtypes Reveals Alterations in Methylation of Genes Involved in the Neuro-Musculoskeletal System.

The Journal of Pain : Official Journal of the American Pain Society
Ludwig StenzBertrand Léger
September 16, 2021

Methylome-wide association study of early life stressors and adult mental health.

Human Molecular Genetics
David M HowardCathryn M Lewis
September 10, 2021

ZFTA-YAP1 fusion-positive ependymoma can occur in the spinal cord: Letter to the editor.

Brain Pathology
Ka Young LimSung-Hye Park
September 10, 2021
Review

Acetyl-L-carnitine in chronic pain: A narrative review.

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Piercarlo Sarzi-PuttiniDiego Fornasari
September 6, 2021
Review

Terpenoid treatment in osteoporosis: this is where we have come in research.

Trends in Endocrinology and Metabolism : TEM
Daniele BellaviaGianluca Giavaresi
September 4, 2021

Discovery of novel hit compounds as potential HDAC1 inhibitors: The case of ligand- and structure-based virtual screening.

Computers in Biology and Medicine
Hajar SirousSimone Brogi

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