Epigenetic Regulation of Microglia Functions

Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.

August 3, 2020

Neuroinflammation and histone H3 citrullination are increased in X-linked Dystonia Parkinsonism post-mortem prefrontal cortex

Neurobiology of Disease
Tiziana PetrozzielloGhazaleh Sadri-Vakili
December 3, 2019
Preprint
Open Access

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

BioRxiv : the Preprint Server for Biology
Ana J Chucair-ElliottWillard M Freeman
April 16, 2020
Review
Open Access

Microglial Corpse Clearance: Lessons From Macrophages

Frontiers in Immunology
Mar Márquez-RoperoAmanda Sierra
June 9, 2020
Open Access

miR-142-3p Regulates BDNF Expression in Activated Rodent Microglia Through Its Target CAMK2A

Frontiers in Cellular Neuroscience
Neelima GuptaS Thameem Dheen
November 5, 2019
Review
Open Access

The Role of Neuronal Factors in the Epigenetic Reprogramming of Microglia in the Normal and Diseased Central Nervous System

Frontiers in Cellular Neuroscience
Tatyana VeremeykoEugene D Ponomarev
December 4, 2019
Open Access

Cx3cr1- deficient microglia exhibit a premature aging transcriptome

Life Science Alliance
Stefka GyonevaRichard M Ransohoff
February 13, 2020
Review
Open Access

Advantages and Limitations of the Neonatal Immune System

Frontiers in Pediatrics
George P TsafarasGeorgina Xanthou
March 18, 2020

How microbiota shape microglial phenotypes and epigenetics

Glia
Daniel Erny, Marco Prinz
April 3, 2020

Behavioral and physiological effects of acute and chronic kava exposure in adult zebrafish

Neurotoxicology and Teratology
Dongmei WangAllan V Kalueff
December 28, 2019
Preprint
Open Access

CSF1R inhibition by a small molecule inhibitor affects hematopoiesis and the function of macrophages.

BioRxiv : the Preprint Server for Biology
Fengyang LeiEleftherios I Paschalis
March 20, 2020

Epigenetic suppression of HIV in myeloid cells by the BRD4-selective small molecule modulator ZL0580

Journal of Virology
Edrous AlamerHaitao Hu
January 11, 2020
Open Access

Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment

Cancer Discovery
Peiwen ChenRonald A DePinho
December 13, 2019
Open Access

Characterization of Blood Surrogate Immune-Methylation Biomarkers for Immune Cell Infiltration in Chronic Inflammaging Disorders

Frontiers in Genetics
Ken Declerck, Wim Vanden Berghe
July 1, 2020

Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma

Journal of Neuropathology and Experimental Neurology
Karen TangMatija Snuderl
April 5, 2020
Review
Open Access

Role of Connexins 30, 36, and 43 in Brain Tumors, Neurodegenerative Diseases, and Neuroprotection

Cells
Oscar F SánchezSonia-Luz Albarracin
April 30, 2020

Pathogenic Infection in Male Mice Changes Sperm Small RNA Profiles and Transgenerationally Alters Offspring Behavior

Cell Reports
Shiraz TyebjiChristopher J Tonkin

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