Epigenetic Regulation of Microglia Functions

Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.

October 16, 2020
Open Access

Multi-omics integration analysis identifies novel genes for alcoholism with potential link to neurodegenerative diseases

BioRxiv : the Preprint Server for Biology
Manav KapoorA. M. Goate
August 3, 2020
Open Access

Neuroinflammation and histone H3 citrullination are increased in X-linked Dystonia Parkinsonism post-mortem prefrontal cortex

Neurobiology of Disease
Tiziana PetrozzielloGhazaleh Sadri-Vakili
September 26, 2020
Open Access

LncRNA MALAT1 facilitates inflammasome activation via epigenetic suppression of Nrf2 in Parkinson's disease

Molecular Brain
Li-Jun CaiJin-Yong Tian
December 11, 2020
Open Access

SAHA attenuates rotenone-induced toxicity in primary microglia and HT-22 cells

Toxicology and Industrial Health
Caner GünaydinNurten Kara
April 16, 2020
Open Access

Microglial Corpse Clearance: Lessons From Macrophages

Frontiers in Immunology
Mar Márquez-RoperoAmanda Sierra
January 2, 2021
Open Access

Balance between Retroviral Latency and Transcription: Based on HIV Model

Aneta PlutaCésar N Cortés-Rubio
June 9, 2020
Open Access

miR-142-3p Regulates BDNF Expression in Activated Rodent Microglia Through Its Target CAMK2A

Frontiers in Cellular Neuroscience
Neelima GuptaS Thameem Dheen
March 18, 2020

How microbiota shape microglial phenotypes and epigenetics

Daniel Erny, Marco Prinz
April 3, 2020

Behavioral and physiological effects of acute and chronic kava exposure in adult zebrafish

Neurotoxicology and Teratology
Dongmei WangAllan V Kalueff
March 20, 2020
Open Access

Epigenetic suppression of HIV in myeloid cells by the BRD4-selective small molecule modulator ZL0580

Journal of Virology
Edrous AlamerHaitao Hu
October 3, 2020

Metabolic Flexibility Assists Reprograming of Central and Peripheral Innate Immunity During Neurodevelopment

Molecular Neurobiology
Gabriela Cruz-Carrillo, Alberto Camacho-Morales
September 18, 2020
Open Access

Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE

The Journal of Experimental Medicine
Tongfei LiuHuaxi Xu
April 5, 2020
Open Access

Role of Connexins 30, 36, and 43 in Brain Tumors, Neurodegenerative Diseases, and Neuroprotection

Oscar F SánchezSonia-Luz Albarracin
November 21, 2020
Open Access

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

Communications Biology
Ana J Chucair-ElliottWillard M Freeman
May 24, 2020
Open Access

Prenatal Exposure to Valproic Acid Affects Microglia and Synaptic Ultrastructure in a Brain-Region-Specific Manner in Young-Adult Male Rats: Relevance to Autism Spectrum Disorders

International Journal of Molecular Sciences
Magdalena Gąssowska-DobrowolskaAgata Adamczyk

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