Epigenetics & Aging

Epigenetic changes, such as changes in histone modification patterns and noncoding RNA expression levels, have a strong influence on the aging process. Discover new insights into the role of epigenetics in aging in this feed.

April 16, 2021

Reconditioning the Neurogenic Niche of Adult Non-human Primates by Antisense Oligonucleotide-Mediated Attenuation of TGFβ Signaling.

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics
Sebastian PetersUlrich Bogdahn
April 15, 2021
Open Access

Aging alters the metabolic flux signature of the ER unfolded protein response in vivo in mice

BioRxiv : the Preprint Server for Biology
Catherine P SchneiderM. Hellerstein
April 16, 2021

RANKL-induced increase in cathepsin K levels restricts cortical expansion in a periostin dependent fashion: a potential new mechanism of bone fragility.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
N BonnetS Ferrari
April 14, 2021
Open Access

Prolonged Lifespan, Ameliorated Cognition, and Improved Host Defense of Caenorhabditis elegans by Lactococcus lactis subsp. cremoris

BioRxiv : the Preprint Server for Biology
T. KomuraYoshikazu Nishikawa
April 14, 2021

Triiodothyronine (T3) enhances lifespan and protects against oxidative stress via activation of Klotho in Caenorhabditis elegans.

Saswat Kumar Mohanty, Kitlangki Suchiang
April 14, 2021
Open Access

The Survey of the Health of Wisconsin (SHOW) Program: An infrastructure for Advancing Population Health Sciences.

MedRxiv : the Preprint Server for Health Sciences
Kristen M C MaleckiPaul E Peppard
April 14, 2021
Open Access

Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.

Rachana TrivediDonald A Jurivich
April 14, 2021

Specific PIWI-interacting RNAs (piRNAs) and related small noncoding RNAs are associated with ovarian aging in Ames dwarf (df/df) mice.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Joseph M DhahbiMichal M Masternak
April 13, 2021

Making Biological Sense of Genetic Studies of Age-Related Macular Degeneration.

Advances in Experimental Medicine and Biology
Nivedita SinghRinki Ratnapriya
April 12, 2021
Open Access

Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling

BioRxiv : the Preprint Server for Biology
L. A. SalasBrock C Christensen
April 12, 2021

Epigenetic and metabolic interplay in cutaneous squamous cell carcinoma.

Experimental Dermatology
Gina Pacella, Brian C Capell
April 12, 2021
Open Access

Aging-associated skeletal muscle defects in HER2/Neu transgenic mammary tumor model.

JCSM Rapid Communications
Ruizhong WangHarikrishna Nakshatri
April 12, 2021

Protective Effects of a Small Molecule Inhibitor, DDQ Against Amyloid Beta in Alzheimer's Disease.

Murali VijayanP Hemachandra Reddy

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