Epigenetics of Beta Cells in T2D

While type 2 diabetes (T2D) is heritable, less than 20% of this heritability is explained by known genetic variants. This discrepancy maybe explained by epigenetic changes and epigenetic inheritance in pancreatic cells. Here is the latest research on the epigenetic control of beta cell function and failure in T2D.

August 6, 2020
Open Access

IL-17F induces inflammation, dysfunction and cell death in mouse islets

Scientific Reports
Tara CatterallAndrew P R Sutherland
August 11, 2020
Open Access

Effect of Thunbergia laurifolia Herbal Tea on Glucose Homeostasis in Healthy Volunteers: A Single-Arm Phase I Study

Evidence-based Complementary and Alternative Medicine : ECAM
Lukana PreechasukNuntakorn Thongtang
August 12, 2020

Age Associated Changes in Transcription of Adiponectin, AdipoR1 and AdipoR2 Genes in Pancreas of Rats

Cell Journal
Marziyeh FeyziMohammad Amin Edalatmanesh
August 4, 2020
Open Access

Novel Technology for Studying Insulin Secretion: Imaging and Quantitative Analysis by a Bioluminescence Method

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Takahiro SuzukiSatoshi Inouye
August 9, 2020

NOD Mice-Good Model for T1D but Not Without Limitations

Cell Transplantation
Virginia R AldrichMidhat H Abdulreda
August 3, 2020
Open Access

Single cell transcriptomics of human islet ontogeny defines the molecular basis of β cell dedifferentiation in T2D

Molecular Metabolism
Dana AvrahamiKlaus H Kaestner
August 5, 2020

Role of sirtuin-1 (SIRT1) in hypoxic injury in pancreatic β-cells

Journal of Drug Targeting
Ye-Jee LeeSeung-Hyun Ko
August 4, 2020

An overview of glucagon-like peptide-1 receptor agonists for the treatment of metabolic syndrome: A drug repositioning

Iranian Journal of Basic Medical Sciences
Maryam RameshradHossein Hosseinzadeh
August 3, 2020

New Mechanisms of Vascular Dysfunction in Cardiometabolic Patients: Focus on Epigenetics

High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension
Samuele AmbrosiniFrancesco Paneni
August 3, 2020

Synthesis of 18 F-labeled streptozotocin derivatives and an in-vivo kinetics study using positron emission tomography

Bioorganic & Medicinal Chemistry Letters
Kenji ArimitsuHiroyuki Kimura
August 7, 2020

TLR4 signals through islet macrophages to alter cytokine secretion during diabetes

The Journal of Endocrinology
Manesh ChittezhathYusuf Ali
August 2, 2020
Open Access

Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

Clinical Epigenetics
Robert F HillaryRiccardo E Marioni
August 11, 2020

Pancreatic complications in children with cystic fibrosis

Current Opinion in Pediatrics
Zachary M Sellers

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