Epigenetics of Myotonic Dystrophy

Myotonic Dystrophy is an autosomal dominant neuromuscular disorder associated with the expansion of CTG trinucleotide repeats in the 3’ untranslated region of the myotonic dystrophy protein kinase (DMPK) gene. Here is the latest research focusing on epigenetic modifications in myotonic dystrophy.

December 11, 2020

DNA methylation at the DMPK gene locus is associated with cognitive functions in myotonic dystrophy type 1.

Édith BretonLuigi Bouchard
November 7, 2020

Epigenetics of neuromuscular disorders.

Fabio Coppedè
September 25, 2020
Open Access

MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells

BioRxiv : the Preprint Server for Biology
Silvie FranckKaren Sermon
November 27, 2019
Open Access

Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat

International Journal of Molecular Sciences
Laurène M AndréBé Wieringa
July 22, 2019
Open Access

Molecular genetics of congenital myotonic dystrophy

Neurobiology of Disease
Stella Lanni, Christopher E Pearson
January 3, 2018
Open Access

Expanded [CCTG]n repetitions are not associated with abnormal methylation at the CNBP locus in myotonic dystrophy type 2 (DM2) patients

Biochimica Et Biophysica Acta. Molecular Basis of Disease
M SantoroA Botta
March 5, 2017
Open Access

CpG Methylation, a Parent-of-Origin Effect for Maternal-Biased Transmission of Congenital Myotonic Dystrophy

American Journal of Human Genetics
Lise BarbéChristopher E Pearson
February 18, 2017
Open Access

Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability

Scientific Reports
Junko UekiHidetoshi Sakurai
January 21, 2017
Open Access

Nuclear Inositide Signaling Via Phospholipase C

Journal of Cellular Biochemistry
Stefano RattiLucia Manzoli
June 11, 2016
Open Access

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Journal of Visualized Experiments : JoVE
Ekaterina BoyarchukSlimane Ait-Si-Ali
January 13, 2016
Open Access

Epigenetics of the myotonic dystrophy-associated DMPK gene neighborhood

Lauren BuckleyMelanie Ehrlich
July 2, 2015
Open Access

Modeling diseases of noncoding unstable repeat expansions using mutant pluripotent stem cells

World Journal of Stem Cells
Shira Yanovsky-DaganRachel Eiges
July 11, 2014
Open Access

Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility

PLoS Genetics
Timothy G JenkinsDouglas T Carrell
August 14, 2013
Open Access

Therapeutic advances in muscular dystrophy

Annals of Neurology
Doris G Leung, Kathryn R Wagner

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