Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.

December 4, 2021
Review

CRISPR/Cas Technologies and Their Applications in Escherichia coli.

Frontiers in Bioengineering and Biotechnology
Huina DongDawei Zhang
October 30, 2021
Review
Open Access

Recent Approaches for Manipulating Globin Gene Expression in Treating Hemoglobinopathies.

Frontiers in Genome Editing
Claudio Mussolino, John Strouboulis
October 24, 2021
Review

Insights of CRISPR-Cas systems in stem cells: progress in regenerative medicine.

Molecular Biology Reports
Shanmugam Dilip KumarMuthupandian Saravanan
October 20, 2021
Open Access

A histidine kinase and a response regulator provide phage resistance to Marinomonas mediterranea via CRISPR-Cas regulation.

Scientific Reports
Patricia Lucas-ElíoAntonio Sánchez-Amat
September 18, 2021
Comment / Editorial

Gene splicing SETs the scene for cocaine addiction.

Neuron
Purva Bali, Paul J Kenny
September 9, 2021

Expanded CAG/CTG repeats resist gene silencing mediated by targeted Epigenome editing.

Human Molecular Genetics
Bin YangVincent Dion
September 2, 2021

Mapping the dynamic transfer functions of eukaryotic gene regulation.

Cell Systems
Jessica B LeeAlbert J Keung
September 1, 2021
Open Access

A Chemical Toolbox for Labeling and Degrading Engineered Cas Proteins.

JACS Au
Rodrigo A Gama-BrambilaXinlai Cheng
August 30, 2021
Open Access

Manipulating the NKG2D Receptor-Ligand Axis Using CRISPR: Novel Technologies for Improved Host Immunity.

Frontiers in Immunology
Eric AlvesSilvana Gaudieri
August 20, 2021

Recent advancements in CRISPR-Cas toolbox for imaging applications.

Critical Reviews in Biotechnology
Vikram Jeet Singh, Mukesh Jain
August 7, 2021
Open Access

Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling.

Cellular and Molecular Gastroenterology and Hepatology
Yeeun ChoiHyoung-Pyo Kim
August 4, 2021
Open Access

Transgenic mice for in vivo epigenome editing with CRISPR-based systems.

Nature Methods
Matthew P GemberlingCharles A Gersbach
July 29, 2021
Open Access

Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis.

Nature Communications
Mengfei LiuVijay H Shah
July 25, 2021
Review

Plant epigenomics for extenuation of abiotic stresses: challenges and future perspectives.

Journal of Experimental Botany
Dharmendra SinghMadan Pal

Sign up to follow this feed and discover related papers.

Related Feeds

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Alzheimer's Disease: RNA Sequencing

RNA sequencing studies have shed light on the genetic and molecular mechanisms related to the pathophysiology of Alzheimer's disease (AD). This feed follows papers using RNA sequencing technologies in Alzheimer's research.

Angelman Syndrome

Angelman syndrome is a neurogenetic imprinting disorder caused by loss of the maternally inherited UBE3A gene and is characterized by generalized epilepsy, limited expressive speech, sleep dysfunction, and movement disorders. Here is the latest research.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Beckwith-Wiedemann syndrome

Beckwith-Wiedemann syndrome is an imprinting disorder characterized by overgrowth, congenital malformations and predisposition to tumors. Discover the latest research on Beckwith-Wiedemann Syndrome here.

CRISPR (general)

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

CRISPR for Genome Editing

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Cancer Epigenetics

Epigenetic changes are present and dysregulated in many cancers, including DNA methylation, non-coding RNA segments and post-translational protein modifications. The epigenetic changes may or may not provide advantages for the cancer cells. Here is the latest research on cancer epigenetics.

Cancer Sequencing

Several sequencing approaches are employed to understand and examine tumor development and progression. These include whole genome as well as RNA sequencing. Here is the latest research on cancer sequencing.

CfDNA Sequencing

Circulating free DNA (cfDNA) are degraded DNA fragments released to the blood plasma. cfDNA has been shown to be a useful biomarker for a multitude of ailments other than cancer and fetal medicine. Here is the latest research on Circulating free DNA (cfDNA) sequencing.

© 2021 Meta ULC. All rights reserved
/feed-previews/epigenome-editing/7ac80f72-1cae-4d9b-b7c6-84edc1f3186e