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Epigenome Editing

Epigenome Editing diagram by qubeat, Wikimedia
qubeat, Wikimedia

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.

Top 20 most recent papers
Proceedings of the National Academy of Sciences of the United States of America

Long-range Pitx2c enhancer-promoter interactions prevent predisposition to atrial fibrillation

Proceedings of the National Academy of Sciences of the United States of AmericaOctober 23, 2019
Min ZhangJames F Martin
14
2
13
Proceedings of the National Academy of Sciences of the United States of America

Biological embedding of experience: A primer on epigenetics

Proceedings of the National Academy of Sciences of the United States of AmericaOctober 19, 2019
Maria J AristizabalKieran J O'Donnell
34
43
1
1
2
Microbiology and Molecular Biology Reviews : MMBR

CRISPR Tools To Control Gene Expression in Bacteria

Microbiology and Molecular Biology Reviews : MMBRApril 3, 2020
Antoine Vigouroux, David Bikard
93
Trends in Neurosciences

Editing the Epigenome to Tackle Brain Disorders

Trends in NeurosciencesNovember 11, 2019
X Shawn Liu, Rudolf Jaenisch
30
31
bioRxiv

JACKIE: Fast enumeration of single- and multi-copy CRISPR binding sites

bioRxivFebruary 28, 2020
Jacqueline Jufen Zhu, Albert Wu Cheng
14
Leukemia

MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells

LeukemiaNovember 27, 2019
Edith SchneiderArefeh Rouhi
SLAS Discovery

Applications of Functional Genomics for Drug Discovery

SLAS DiscoveryFebruary 7, 2020
Ami KabadiLauren Drowley
16
Yi chuan = Hereditas

Probing 3D genome by CRISPR/Cas9

Yi chuan = HereditasJanuary 21, 2020
Pei Feng Liu, Qiang Wu
1
Essays in Biochemistry

Harnessing targeted DNA methylation and demethylation using dCas9

Essays in BiochemistryNovember 15, 2019
Christian PfluegerRyan Lister
Trends in Plant Science

Revisiting the Role of Master Regulators in Tomato Ripening

Trends in Plant ScienceJanuary 14, 2020
Rufang WangRuud A de Maagd
4
Biochemical Society Transactions

Characterization and applications of Type I CRISPR-Cas systems

Biochemical Society TransactionsJanuary 11, 2020
Claudio Hidalgo-Cantabrana, Rodolphe Barrangou
Scientific Reports

Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing

Scientific ReportsMarch 22, 2020
Nozomi HanzawaYoshihiro Ogawa
2

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