Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.

July 4, 2020
Open Access

Technologies and Computational Analysis Strategies for CRISPR Applications

Molecular Cell
Kendell ClementLuca Pinello
April 15, 2020

F. novicida CRISPR-Cas systems can functionally complement each other in DNA defense while providing target flexibility

Journal of Bacteriology
Hannah K Ratner, David S Weiss
April 23, 2020
Open Access

ZNF143 in Chromatin Looping and Gene Regulation

Frontiers in Genetics
Bingyu YeGuoying Yu
April 23, 2020
Open Access

CRISPR/Cas9 Epigenome Editing Potential for Rare Imprinting Diseases: A Review

Linn Amanda SydingRadislav Sedlacek
September 10, 2020
Open Access

Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases

Frontiers in Molecular Neuroscience
Joseph Edward RittinerBoris Kantor
February 28, 2020
Open Access

JACKIE: Fast enumeration of single- and multi-copy CRISPR binding sites

BioRxiv : the Preprint Server for Biology
Jacqueline Jufen Zhu, Albert Wu Cheng
August 24, 2020
Open Access

Efficient genome editing in pathogenic mycobacteria using Streptococcus thermophilus CRISPR1-Cas9

Aniek S MeijersCoenraad P Kuijl
September 16, 2020
Open Access

UQCRH downregulation promotes Warburg effect in renal cell carcinoma cells

Scientific Reports
Yanting LuoXin Lu
May 8, 2020
Open Access

Massively parallel CRISPRi assays reveal concealed thermodynamic determinants of dCas12a binding

Proceedings of the National Academy of Sciences of the United States of America
David A SpechtGuillaume Lambert
July 8, 2020
Open Access

Therapeutic Editing of the TP53 Gene: Is CRISPR/Cas9 an Option?

Regina MirgayazovaEmil Bulatov
May 3, 2020
Comment / Editorial

Decoding the Noncoding Cancer Genome

Cancer Discovery
Peter van Galen
June 17, 2020
Open Access

Integrative computational epigenomics to build data-driven gene regulation hypotheses

Tyrone Chen, Sonika Tyagi
June 10, 2020
Open Access

Various strategies of effector accumulation to improve the efficiency of genome editing and derivative methodologies

In Vitro Cellular & Developmental Biology. Animal
Atsushi KuniiTetsushi Sakuma
May 30, 2020

CRISPR/Cas9-Based Transcriptional Activation of Endogenous IL-10 Gene in the Donor Lung for Transplantation

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
K MesakiS Keshavjee
May 16, 2020

Comprehensive Mining and Characterization of CRISPR-Cas Systems in Bifidobacterium

Meichen PanRodolphe Barrangou

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