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Epigenome Engineering (Keystone)

Epigenome Engineering (Keystone) diagram by undefined

Recent advances in epigenome engineering technologies allow now for the large-scale assessment of the functional relevance of DNA methylation. Discover the latest research here.

Top 20 most recent papers
Nature Genetics

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Nature GeneticsFebruary 19, 2020
Maria Gutierrez-ArcelusSoumya Raychaudhuri
Nature Cell Biology

Programmable base editing of mutated TERT promoter inhibits brain tumour growth

Nature Cell BiologyFebruary 19, 2020
Xinjian LiZhimin Lu
Journal of Thrombosis and Haemostasis : JTH

Identification and functional characterization of a novel splicing variant in the F8 coagulation gene causing severe hemophilia A

Journal of Thrombosis and Haemostasis : JTHFebruary 21, 2020
Rosella FamàAntonia Follenzi
Nucleic Acids Research

Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma

Nucleic Acids ResearchFebruary 22, 2020
Xiang Yi KongIngrun Alseth
Genesis : the Journal of Genetics and Development

CRISPR/Cas9 engineering of albino cystinuria Type A mice

Genesis : the Journal of Genetics and DevelopmentFebruary 21, 2020
Thomas M BeckermannMatthew H Wilson

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

bioRxivFebruary 20, 2020
Anne Ramsay BowdenSteve Jackson
Nucleic Acids Research

A memory switch for plant synthetic biology based on the phage ϕC31 integration system

Nucleic Acids ResearchFebruary 22, 2020
Joan Miquel Bernabé-OrtsDiego Orzaez
Current Opinion in Structural Biology

Allosteric regulation of CRISPR-Cas9 for DNA-targeting and cleavage

Current Opinion in Structural BiologyFebruary 20, 2020
Zhicheng Zuo, Jin Liu
Frontiers in Plant Science

Identification of an SCPL Gene Controlling Anthocyanin Acylation in Carrot (Daucus carota L.) Root

Frontiers in Plant ScienceFebruary 22, 2020
Julien CurabaMassimo Iorizzo
International Journal of Molecular Sciences

Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in vivo Genome Editing

International Journal of Molecular SciencesFebruary 23, 2020
Giovanni PasquiniVolker Busskamp
ACS Nano

Intracellular Nanomaterial Delivery via Spiral Hydroporation

ACS NanoFebruary 19, 2020
GeoumYoung KangAram J Chung

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