Epigenome Engineering

Recent advances in epigenome engineering technologies allow now for the large-scale assessment of the functional relevance of dna methylation. Discover the latest research here.

February 24, 2021

Long-term maturation of human cortical organoids matches key early postnatal transitions.

Nature Neuroscience
Aaron GordonDaniel H Geschwind
February 23, 2021
Preprint
Open Access

Seven amino acid types suffice to reconstruct the core fold of RNA polymerase

BioRxiv : the Preprint Server for Biology
S. YagiShunsuke Tagami
February 23, 2021
Open Access

Degradation of mitochondrial structure and deficiency of complex I were associated with the transgenic CMS of rice.

Biological Research
Danfeng TangRuiyang Zhou
February 23, 2021
Review
Open Access

The Role of the Z-DNA Binding Domain in Innate Immunity and Stress Granules.

Frontiers in Immunology
De Chen ChiangSiew Kit Ng
February 23, 2021
Review
Open Access

The Versatile Type V CRISPR Effectors and Their Application Prospects.

Frontiers in Cell and Developmental Biology
Baisong TongDawei Zhang
February 23, 2021
Open Access

Development and Characterization of a Modular CRISPR and RNA Aptamer Mediated Base Editing System.

The CRISPR Journal
Juan Carlos CollantesShengkan Jin
February 21, 2021
Open Access

Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement.

Science Advances
Evan A BoyleWilliam J Greenleaf
February 21, 2021
Open Access

Efficient genome editing with CRISPR/Cas9 in Pleurotus ostreatus.

AMB Express
Tatpong BoontawonYoichi Honda
February 21, 2021
Review

Mini review: genome and transcriptome editing using CRISPR-cas systems for haematological malignancy gene therapy.

Transgenic Research
Esther K ElliottLyn R Griffiths
February 20, 2021
Open Access

Harnessing A3G for efficient and selective C-to-T conversion at C-rich sequences.

BMC Biology
Wenxia YuXingxu Huang
February 20, 2021
Review
Open Access

Using CRISPR to enhance T cell effector function for therapeutic applications.

Cytokine: X
Julian J Freen-van Heeren
February 20, 2021
Open Access

CRISPR Turbo Accelerated KnockOut (CRISPy TAKO) for Rapid in vivo Screening of Gene Function.

Frontiers in Genome Editing
Sonja L PlasilGregg E Homanics
February 19, 2021

Accurate deep learning off-target prediction with novel sgRNA-DNA sequence encoding in CRISPR-Cas9 gene editing.

Bioinformatics
Jeremy CharlierVladimir Makarenkov
February 19, 2021
Review
Open Access

Review on circular RNAs and new insights into their roles in cancer.

Computational and Structural Biotechnology Journal
Xiaozhu TangChunyan Gu

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