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Epigenome Engineering

Epigenome Engineering diagram by Mari-Leaf, Shutterstock
Mari-Leaf, Shutterstock

Recent advances in epigenome engineering technologies allow now for the large-scale assessment of the functional relevance of dna methylation. Discover the latest research here.

Top 20 most recent papers
BMC Genomics

Enhanced genome assembly and a new official gene set for Tribolium castaneum

BMC GenomicsJanuary 16, 2020
Nicolae HerndonGregor Bucher

ATF4 mediates fetal globin upregulation in response to reduced β-globin

bioRxivJanuary 15, 2020
Mandy Y BoontanrartJacob E Corn

On the origin and evolution of RNA editing in metazoans

bioRxivJanuary 19, 2020
Qiye LiGuojie Zhang

Improved bacterial recombineering by parallelized protein discovery

bioRxivJanuary 16, 2020
Timothy M WannierGeorge M Church
Human Molecular Genetics

Naturally occurring NOTCH3 exon skipping attenuates NOTCH3 protein aggregation and disease severity in CADASIL patients

Human Molecular GeneticsJanuary 22, 2020
Gido GravesteijnJulie W Rutten
Breast Cancer Research : BCR

p66ShcA functions as a contextual promoter of breast cancer metastasis

Breast Cancer Research : BCRJanuary 17, 2020
Kyle LewisJosie Ursini-Siegel

Evolutionary forces on A-to-I RNA editing revealed by sequencing individual honeybee drones

bioRxivJanuary 15, 2020
Yuange DuanJian Lu
Psychological Medicine

Prospective evaluation of the DSM-5 persistent complex bereavement disorder criteria in adults: dimensional and diagnostic approaches

Psychological MedicineJanuary 17, 2020
Elie G AounDavid A Brent
BMC Biology

Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation

BMC BiologyJanuary 16, 2020
Elin LundinMats Nilsson
The Journal of Clinical Investigation

Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis

The Journal of Clinical InvestigationJanuary 17, 2020
Jeongeun HyunAnna Mae Diehl
Molecular Microbiology

A link between mitochondrial gene expression and life stage morphologies in Trypanosoma cruzi

Molecular MicrobiologyJanuary 22, 2020
Roger Ramirez-BarriosSara L Zimmer
Nucleic Acids Research

DNA targeting by Clostridium cellulolyticum CRISPR-Cas9 Type II-C system

Nucleic Acids ResearchJanuary 17, 2020
Iana FedorovaKonstantin Severinov

Antagonistic cooperativity between crystal growth modifiers

NatureJanuary 17, 2020
Wenchuan MaPeter G Vekilov

GRK2 enforces androgen receptor dependence in the prostate and prostate tumors

OncogeneJanuary 22, 2020
Adam J AdlerAnthony T Vella
Nano Letters

Ionizable Lipid Nanoparticle Mediated mRNA Delivery for Human CAR T Cell Engineering

Nano LettersJanuary 18, 2020
Margaret BillingsleyMichael J Mitchell
Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society

New approaches to genetic therapies for cystic fibrosis

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis SocietyJanuary 18, 2020
A Christopher BoydStephen L Hart

A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing

RNAJanuary 17, 2020
Pedro Henrique Costa CruzYukio Kawahara

FYN tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates anti-glioma immune responses

Neuro-oncologyJanuary 18, 2020
Andrea CombaPedro R Lowenstein
Pest Management Science

Molecular characterization and functional expression of voltage-gated sodium channel variants in Apolygus lucorum (Meyer-Dür)

Pest Management ScienceJanuary 17, 2020
Kun ZhangShaoying Wu
Nucleic Acids Research

An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype

Nucleic Acids ResearchJanuary 21, 2020
Prajakta BajadMichael F Jantsch

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