Several protein complexes are present on the ER membrane that facilitates the protein translocation across and into the ER where folding can occur. Discover the latest research on ER Membrane: Protein Translocation here.
Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. Here is the latest research on basement membranes.
Lipids are essential in many biological functions, including membrane structure, energy storage, and cell signaling. Find the latest research on the cell biology of lipids here.
Dynamin GTPases are proteins that are responsible for endocytosis in cells, as well as division of organelles, cytokinesis, and pathogen resistance. Discover the latest research on dynamin GTPases here.
Adsorptive and receptor-mediated endocytosis via clathrin-coated vesicles provides the major and best-characterized portal for uptake of multiple molecules and particles into cells. Via clathrin-dependent endocytosis, cells receive nutrients, regulate receptors and other plasma membrane constituents, take up antigens, and remove senescent, excess, and potentially harmful substances from the extracellular fluid. Discover the latest research on endocytic system here.
Extracellular vesicles are cell-derived structures containing complex cargo, including proteins and nucleic acids, that originate from endosomal systems or the plasma membrane. Here is the latest research on technologies for the analysis of extracellular vesicles.
Extracellular vesicles are implicated in propagating toxic amyloid proteins in neurodegenerative disorders. Here is the latest research on extracellular vesicles including exosomes in the CNS.
Glycosylphosphatidylinositol (GPI) is a glycolipid anchor for several cell-surface proteins that play a role in various biological processes, including signal transduction, prion disease pathogenesis, and immune response. Here is the latest research.
GTPases, including small ras sub-families and large dynamin are regulators of intracellular trafficking. They are implicated in vesicular transport and important for the communication within cells. Discover the latest search on GTPases in intracellular trafficking here.
Gap junctions are specialized intercellular communication channels that transfer molecules between neighboring cells and thereby alter intracellular signaling and metabolism. Here is the latest research on the influence of gap junctions on intercellular signaling.