Exon Skipping

Exon skipping is a method of RNA splicing used when a mutation occurs in the genes of exons. It is regulated largely by the use of antisense oligonucleotides that mask the mutated gene and allow the cellular machinery to skip over it. Exon skipping is being investigated as a therapeutic option for some diseases. Here is the latest research on exon skipping.

December 7, 2021

A YAP1::TFE3 Cutaneous Low-Grade Fibromyxoid Neoplasm: A Novel Entity!

Genes, Chromosomes & Cancer
Ashley PattonO Hans Iwenofu
December 7, 2021

Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD.

Acta Neuropathologica
Kathryn R BowlesAlison M Goate
December 7, 2021
Open Access

Single-cell characterization of CRISPR-modified transcript isoforms with nanopore sequencing.

Genome Biology
Heon Seok KimHanlee P Ji
December 7, 2021

First patient in the Iranian Registry with novel DOCK2 gene mutation, presenting with skeletal tuberculosis, and review of literature.

Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Niusha SharifinejadGholamreza Azizi
December 6, 2021
Review
Open Access

Diverse Roles and Therapeutic Potentials of Circular RNAs in Urological Cancers.

Frontiers in Molecular Biosciences
Song WangLiping Xie
December 6, 2021
Open Access

Dynamic Expression and Regulatory Network of Circular RNA for Abdominal Preadipocytes Differentiation in Chicken (Gallus gallus).

Frontiers in Cell and Developmental Biology
Weihua TianChangxin Wu
December 6, 2021
Open Access

TMPRSS3 Gene Variants With Implications for Auditory Treatment and Counseling.

Frontiers in Genetics
In Seok MoonKonstantina M Stankovic
December 6, 2021
Case Report
Open Access

Case Report: A Synonymous Mutation in NF1 Located at the Non-canonical Splicing Site Leading to Exon 45 Skipping.

Frontiers in Genetics
Pengzhen JinMinyue Dong
December 6, 2021
Case Report

Complete Remission to Afatinib in a Patient Harboring a Novel Epidermal Growth Factor Mutation in De Novo Small-Cell Lung Cancer: A Case Report: Clinical Lung Cancer.

Clinical Lung Cancer
Maximilian Johannes HochmairArschang Valipour
December 6, 2021
Review

Overall Treatment Strategy for Patients With Metastatic NSCLC With Activating EGFR Mutations.

Clinical Lung Cancer
Hidetoshi HayashiChristian Grohe
December 6, 2021

Alternative Splicing Events in Immune Infiltration of Lung Adenocarcinoma.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Tianpeng HuangXuejiao Lin
December 6, 2021

Exon skipping therapy for DMD.

Journal of Neuromuscular Diseases
December 6, 2021

A case of VEXAS syndrome associated with EBV-associated hemophagocytic lymphohistiocytosis.

Blood Cells, Molecules & Diseases
Roy L KaoDavid R Pearson
December 6, 2021

Generation of heterozygous (MRli003-A-1) and homozygous (MRli003-A-2) MYH10 knockout human iPSC lines.

Stem Cell Research
Fangfang ZhangAlessandra Moretti
December 6, 2021

Genome-wide variant calling in reanalysis of exome sequencing data uncovered a pathogenic TUBB3 variant.

European Journal of Medical Genetics
Elke de BoerLisenka E L M Vissers
December 6, 2021
Open Access

Compound heterozygous c.598_612del and c.1746-20C > G CAPN3 genotype cause autosomal recessive limb-girdle muscular dystrophy-1: a case report.

BMC Musculoskeletal Disorders
Evelina SiavrienėEglė Preikšaitienė
December 5, 2021
Preprint
Open Access

Environmentally-induced DNA methylation is inherited across generations in an aquatic keystone species (Daphnia magna)

BioRxiv : the Preprint Server for Biology
Nathalie FeinerT. Uller

Sign up to follow this feed and discover related papers.

Related Feeds

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Artificial Chromosomes

Artificial chromosomes are genetically engineered chromosomes derived from the DNA of a species. Discover the latest research on artificial chromosomes here.

Biodiversity Data

Biodiversity refers to the variety and variability of life on Earth. Biodiversity is typically a measure of variation at the genetic, species, and ecosystem level.Discover the latest research on biodiversity data here.

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

CRISPR & Single Cell Analyses

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on CRISPR-Cas applications relevant to single cell analyses. Here is the latest research.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

CRISPR (general)

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

CRISPR Genome Editing & Therapy

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

CRISPR Ribonucleases Deactivation

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on mechanisms that underlie deactivation of CRISPR ribonucleases. Here is the latest research.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

© 2021 Meta ULC. All rights reserved
/feed-previews/exon-skipping/e2b35049-d0db-4937-af14-1947ad432e2f