FGF21 in Food Choice & Metabolism

Fibroblast growth factor 21 (FGF21) is a liver‐derived hormone with pleiotropic metabolic effects. FGF21 selectively inhibits consumption of sugars, but not fat, protein or complex carbohydrates. Discover the latest research on FGF21 in food choice and metabolism here.

September 20, 2021

GWAS META-analysis followed by MENDELIAN randomisation revealed potential control mechanisms for circulating α-klotho levels.

Human Molecular Genetics
Ingrid GergeiJonathan H Tobias
September 18, 2021

FGF21 ameliorates hepatic fibrosis by multiple mechanisms.

Molecular Biology Reports
Fanrui MengDeshan Li
September 16, 2021

Another kid on the block: long-acting FGF21 analog to treat dyslipidemia and fatty liver.

The Journal of Clinical Endocrinology and Metabolism
Ranyao YangAlexei Kharitonenkov
September 8, 2021
Open Access

Homocysteine-induced endoplasmic reticulum stress activates FGF21 via CREBH, resulting in browning and atrophy of white adipose tissue in Bhmt knockout mice.

BioRxiv : the Preprint Server for Biology
Isis Trujillo-GonzalezK. Zhang
September 6, 2021
Open Access

ImmTOR nanoparticles enhance AAV transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia.

Molecular Therapy. Methods & Clinical Development
Petr O IlyinskiiTakashi Kei Kishimoto
August 28, 2021

Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure.

Journal of Hepatology
Ingrid W ZhangJoan Clària
August 23, 2021
Open Access

A Differential Pattern of Batokine Expression in Perivascular Adipose Tissue Depots From Mice.

Frontiers in Physiology
Alberto Mestres-ArenasMarion Peyrou
August 18, 2021

Impaired brown adipose tissue is differentially modulated in insulin-resistant obese wistar and type 2 diabetic Goto-Kakizaki rats.

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Tamires Duarte Afonso SerdanSandro Massao Hirabara
August 7, 2021
Open Access

Fibroblast Growth Factor 21 Response in a Preclinical Alcohol Model of Acute-on-Chronic Liver Injury.

International Journal of Molecular Sciences
Grigorios ChristidisSenem Ceren Karatayli
July 30, 2021
Open Access

FGF21 Promotes Proliferation and Estradiol Synthesis in Porcine Granulosa Cells

Yamei HuGuiyan Chu
July 28, 2021
Open Access

Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1.

JCI Insight
Yang CaoQin Yang
July 1, 2021
Open Access

FGF21 defines a potential cardio-hepatic signaling circuit in human heart failure

MedRxiv : the Preprint Server for Health Sciences
S. SommakiaDipayan Chaudhuri
July 1, 2021
Open Access

FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes.

Cell Reports
Mohammad Abu-OdehAlan R Saltiel
June 26, 2021

Adipokines in metabolic and reproductive functions in birds: An overview of current knowns and unknowns.

Molecular and Cellular Endocrinology
Ophélie BernardiJoëlle Dupont
June 25, 2021

Circulating fibroblast growth factor 21 as a potential biomarker for missed abortion in humans.

Fertility and Sterility
Yongkang YangYao Wang

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