FLT3 Inhibitors in Acute Myeloid Leukemia

FMS related tyrosine kinase 3 (FLT3) is a frequently mutated receptor tyrosine kinase in Acute Myeloid Leukemia. Novel Tyrosine kinase inhibitors against FLT3 are currently in clinical trial. Discover the latest research on FLT3 Inhibitors in Acute Myeloid Leukemia here.

January 9, 2021

A novel prognostic scoring model for newly diagnosed FLT3-ITD-positive acute myeloid leukemia

American Journal of Cancer Research
Yi ZhangJie Jin
December 6, 2020
Open Access

Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia

Cancer Discovery
Bhavana BhatnagarAnn-Kathrin Eisfeld
November 10, 2020

Importance of gene mutation analysis as prognostic factor of acute myeloid leukemia

[Rinshō ketsueki] The Japanese journal of clinical hematology
Hiroki Yamaguchi
January 14, 2021

Serine biosynthesis is a metabolic vulnerability in FLT3-ITD-driven acute myeloid leukaemia

Cancer Discovery
Stefan BjelosevicRicky W Johnstone
November 25, 2020
Open Access

Outcomes of pediatric acute myeloid leukemia patients with FLT3-ITD mutations in the pre-FLT3 inhibitor era

Blood Research
Sujin ChoiHyoung Jin Kang
November 21, 2020
Case Report

Successful bridge therapy of gilteritinib to cord blood transplantation in relapsed acute myeloid leukemia after bone marrow transplantation

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Iku KamitaniShingo Yano
January 8, 2021
Open Access

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3-ITD-driven acute myeloid leukemia

FEBS Open Bio
Rosa G Lopez-ReyesManuel S Rodriguez
December 16, 2020
Open Access

Hyperleukocytosis predicts inferior clinical outcome in pediatric acute myeloid leukemia

Lu-Hong XuFeng-Ying Yang
November 11, 2020
Open Access

Discovery of Oxazol-2-amine Derivatives as Potent Novel FLT3 Inhibitors

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Hyo Jeong KimJiyeon Ahn
December 9, 2020

Nanopore sequencing sheds a light on the FLT3 gene mutations complexity in acute promyelocytic leukemia

Leukemia & Lymphoma
Cosimo CumboFrancesco Albano
January 17, 2021
Open Access

Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines

Molecular & Cellular Proteomics : MCP
Carolien van AlphenConnie R Jimenez

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