G-Protein-Coupled Receptors (Preprints)

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here are the latest preprints on GPCRs.

January 15, 2022
Preprint
Open Access

BitterMatch: Recommendation systems for matching molecules with bitter taste receptors

BioRxiv : the Preprint Server for Biology
E. MargulisMasha Y Niv
January 14, 2022
Preprint
Open Access

Location bias contributes to functionally selective responses of biased CXCR3 agonists

BioRxiv : the Preprint Server for Biology
D. S. EigerSudarshan Rajagopal
January 13, 2022
Preprint
Open Access

Proteasome granular localization is regulated through mitochondrial respiration and kinase signaling

BioRxiv : the Preprint Server for Biology
K. A. Waite, Jeroen Roelofs
January 12, 2022
Preprint
Open Access

The Mechanisms of GPR55 Receptor Functonal Selectivity

BioRxiv : the Preprint Server for Biology
Mikhail G AkimovV. V. Bezuglov
January 12, 2022
Preprint
Open Access

Cell adhesion and immune response, two main functions altered in the transcriptome of seasonally regressed testes of two mammalian species

BioRxiv : the Preprint Server for Biology
F. M. RealF. J. Barrionuevo
January 12, 2022
Preprint
Open Access

Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo

BioRxiv : the Preprint Server for Biology
J. SinghDominic Winter
January 12, 2022
Preprint
Open Access

Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

BioRxiv : the Preprint Server for Biology
Y. GuanZekun Guo
January 12, 2022
Preprint
Open Access

Uncovering potential interventions for pancreatic cancer patients via mathematical modeling

BioRxiv : the Preprint Server for Biology
Daniel R PlaugherD. Murrugarra
January 12, 2022
Preprint
Open Access

Engineered cell differentiation and sexual reproduction in probiotic and mating yeasts

BioRxiv : the Preprint Server for Biology
Emil D. JensenEmil D. Jensen
January 11, 2022
Preprint
Open Access

Collagen XVIII promotes breast cancer through EGFR/ErbB signaling and its ablation improves the efficacy of ErbB-targeting inhibitors

BioRxiv : the Preprint Server for Biology
R. DevarajanRitva Heljasvaara
January 11, 2022
Preprint
Open Access

Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

BioRxiv : the Preprint Server for Biology
M. BaidyaArun K Shukla
January 9, 2022
Preprint
Open Access

Developmental patterning function of GNOM ARF-GEF mediated from the plasma membrane

BioRxiv : the Preprint Server for Biology
M. AdamowskiJiří Friml
January 9, 2022
Preprint
Open Access

SH3Ps recruit auxilin-like vesicle uncoating factors into clathrin-mediated endocytosis

BioRxiv : the Preprint Server for Biology
M. AdamowskiJiří Friml
January 9, 2022
Preprint
Open Access

Characterization of CAP1 and ECA4 adaptors participating in clathrin-mediated endocytosis

BioRxiv : the Preprint Server for Biology
M. AdamowskiJiří Friml
January 8, 2022
Preprint
Open Access

Dissecting conformational rearrangements and allosteric modulation in metabotropic glutamate receptor activation

BioRxiv : the Preprint Server for Biology
N. Lecat-GuilletEmmanuel Margeat
January 7, 2022
Preprint
Open Access

Covariant Fitness Clusters Reveal Structural Evolution of SARS-CoV-2 Polymerase Across the Human Population

BioRxiv : the Preprint Server for Biology
C. WangWilliam E Balch
January 7, 2022
Preprint
Open Access

Autoantibody and hormone activation of the thyrotropin G protein-coupled receptor

BioRxiv : the Preprint Server for Biology
B. FaustAashish Manglik
January 7, 2022
Preprint
Open Access

Rnf149-related is an FGF/MAPK-independent regulator of pharyngeal muscle fate specification

BioRxiv : the Preprint Server for Biology
B. VitrinelLionel Christiaen
January 7, 2022
Preprint
Open Access

A kinase translocation reporter reveals real-time dynamics of ERK activity in Drosophila

BioRxiv : the Preprint Server for Biology
A. C. YuenMarc Amoyel
January 6, 2022
Preprint
Open Access

Multifunctional role of GPCR signaling in epithelial tube formation

BioRxiv : the Preprint Server for Biology
V. VishwakarmaSeYeon Chung

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