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G-Protein-Coupled Receptors (Preprints)

G-Protein-Coupled Receptors (Preprints)   diagram by undefined

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here are the latest preprints on GPCRs.

Top 20 most recent papers
bioRxiv

Targeting dual signaling pathways in concert with immune checkpoints for the treatment of pancreatic cancer

bioRxivDecember 5, 2019
Erik S. KnudsenAgnieszka K. Witkiewicz
14
bioRxiv

Uncovering patterns of atomic interactions in static and dynamic structures of proteins

bioRxivNovember 13, 2019
A. J. VenkatakrishnanRon O. Dror
26
bioRxiv

Multiple Low Dose therapy: an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours

bioRxivOctober 29, 2019
Joao Manuel Fernandes NetoRene R. Bernards
25
bioRxiv

Downregulation of GPR183 on Infection Restricts the Early Infection and Intracellular Survival of Mycobacterium tuberculosis in Macrophage

bioRxivNovember 6, 2019
Jun TangChuan Qin
3
bioRxiv

Beta 1 Integrin Signaling Mediates Pancreatic Ductal Adenocarcinoma Resistance to MEK Inhibition

bioRxivDecember 3, 2019
Arthur L BrannonMarina Pasca di Magliano
6
bioRxiv

A trafficome-wide RNAi screen reveals deployment of early and late secretory host proteins and the entire late endo-/lysosomal vesicle fusion machinery by intracellular Salmonella

bioRxivNovember 19, 2019
Alexander KehlMichael Hensel
4
bioRxiv

Co-ordinated regulation of cell survival and cell cycle pathways by DDR2-dependent SRF transcription factor in cardiac fibroblasts

bioRxivNovember 27, 2019
Allen Sam TitusShivakumar Kailasam
1
bioRxiv

Phosphorylation of the CAMTA3 transcription factor triggers its destabilization and nuclear export.

bioRxivOctober 30, 2019
Xiyuan JiangJustin Lee
8
bioRxiv

The metastable human brain associated with autistic-like traits

bioRxivNovember 26, 2019
Takumi Sase, Keiichi Kitajo
3
bioRxiv

Grb2 binding induces phosphorylation-independent activation of Shp2

bioRxivNovember 29, 2019
Chi-Chuan LinJohn Edward Ladbury
7
bioRxiv

An accurate molecular method to sex elephants using PCR amplification of Amelogenin gene

bioRxivNovember 26, 2019
George Gwaltu Lohay
3
bioRxiv

pSpatiocyte: a high-performance simulator for intracellular reaction-diffusion systems

bioRxivNovember 30, 2019
Satya Nanda Vel ArjunanKoichi Takahashi
2
bioRxiv

Structure of the human BBSome core complex in the open conformation

bioRxivNovember 17, 2019
Björn Udo KlinkStefan Raunser
56
bioRxiv

The apparent requirement for protein synthesis during G2 phase is due to checkpoint activation

bioRxivDecember 3, 2019
Sarah LockheadJames E. Ferrell
2
bioRxiv

A complex structure of arrestin-2 bound to a G protein-coupled receptor

bioRxivOctober 29, 2019
Wanchao YinH. Eric Xu
34
bioRxiv

Lipid-mediated insertion of Toll-like receptor (TLR) ligands for facile immune cell engineering

bioRxivNovember 16, 2019
Michael H. ZhangGregory Lee Szeto
21
bioRxiv

Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

bioRxivNovember 5, 2019
Dorien A. RoosenMark Robert Cookson
31
bioRxiv

Junctophilin-4 is essential for signalling at plasma membrane-endoplasmic reticulum junctions in sensory neurons

bioRxivNovember 15, 2019
Alexandra HogeaNikita L Gamper
4
bioRxiv

p38-mitogen activated kinases mediate a developmental regulatory response to amino acid depletion and associated oxidative stress in mouse blastocyst embryos

bioRxivOctober 21, 2019
Pablo BoraAlexander William Bruce
2
bioRxiv

Deoxynivalenol Promotes Porcine Epidemic Diarrhea Virus Infection and Aggravates Gut Barrier Injury

bioRxivNovember 22, 2019
Ke-he HuangChun-feng Wang
6

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