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G-Protein-Coupled Receptors (Preprints)

G-Protein-Coupled Receptors (Preprints)   diagram by ellepigrafica, Shutterstock
ellepigrafica, Shutterstock

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here are the latest preprints on GPCRs.

Top 20 most recent papers
bioRxiv

Elevated phosphate mediates extensive cellular toxicity: from abnormal proliferation to cell death

bioRxivJanuary 2, 2020
Ping HeMohammed S. Razzaque
4
bioRxiv

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.

bioRxivDecember 27, 2019
Kazuhiro KobayashiOsamu Nureki
36
bioRxiv

Convergent Met and voltage-gated Ca2+ channel signaling on Ras-Erk MAPK drives migratory activation of dendritic cells parasitized by Toxoplasma gondii

bioRxivJanuary 8, 2020
Einar B OlafssonAntonio Barragan
11
bioRxiv

SopB- and SifA-dependent shaping of the Salmonella-containing vacuole proteome in the social amoeba Dictyosteliumdiscoideum

bioRxivDecember 28, 2019
Camila ValenzuelaCarlos A Santiviago
4
bioRxiv

Unacylated ghrelin and AZP531 suppress the 3D growth of breast cancers

bioRxivJanuary 23, 2020
CheukMan C AuKristy A Brown
bioRxiv

RFDTI: Using Rotation Forest with Feature Weighted for Drug-Target Interaction Prediction from Drug Molecular Structure and Protein Sequence

bioRxivJanuary 6, 2020
lei wangXin Yan
6
bioRxiv

Development of novel anti-malarial from structurally diverse library of molecules, targeting plant-like Calcium Dependent Protein Kinase 1, a multistage growth regulator of P. falciparum

bioRxivJanuary 15, 2020
Ravi Jainshailja singh
6
bioRxiv

Swimming ghosts of the halophilic archaeon, Haloferax volcanii

bioRxivJanuary 9, 2020
Yoshiaki KinositaRichard Berry
13
bioRxiv

Improved multi-type birth-death phylodynamic inference in BEAST 2

bioRxivJanuary 6, 2020
Jeremie ScireTanja Stadler
11
bioRxiv

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

bioRxivJanuary 9, 2020
Mie F. PedersenHans Bräuner-Osborne
12
bioRxiv

RosettaGPCR: Multiple Template Homology Modeling of GPCRs with Rosetta

bioRxivDecember 13, 2019
Brian J BenderJens Meiler
23
1
bioRxiv

Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis

bioRxivJanuary 13, 2020
Andrew B TobinGraeme Milligan
12
bioRxiv

FGFR/Heartless and Smog interact synergistically to negatively regulate Fog mediated GPCR signaling.

bioRxivDecember 30, 2019
Kumari ShwetaAnuradha Ratnaparkhi
5
bioRxiv

GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

bioRxivJanuary 23, 2020
Natura MyekuKaren E Duff
bioRxiv

An exhaustive analysis of single amino acid variants in helical transmembrane proteins

bioRxivDecember 19, 2019
Oscar Llorian-SalvadorBurkhard Rost
5
bioRxiv

Anti-inflammatory properties of chemical probes in human whole blood: focus on prostaglandin E2 production

bioRxivDecember 30, 2019
Filip BergqvistLouise Berg
1
bioRxiv

A novel cross talk of AtRAV1, an ethylene responsive transcription factor with MAP kinases imparts broad spectrum disease resistance in plants

bioRxivJanuary 9, 2020
Ravindra Kumar ChandanGopaljee Jha
11
bioRxiv

Mining downy mildew susceptibility genes: a diversity study in grapevine.

bioRxivJanuary 15, 2020
Carlotta PirrelloSilvia Vezzulli
8
bioRxiv

In vivo electrophysiological validation of DREADD-based inhibition of pallidal neurons in the non-human primate.

bioRxivJanuary 3, 2020
Marc DeffainsThomas Boraud
30
bioRxiv

The G-protein coupled receptor SRX-97 is required for concentration dependent sensing of Benzaldehyde in Caenorhabditis elegans

bioRxivJanuary 6, 2020
Nagesh Y. KadamKavita Babu
9

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