G-Protein-Coupled Receptors (Preprints)

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here are the latest preprints on GPCRs.

January 17, 2021
Preprint
Open Access

Formation and Spontaneous Long-Term Repatterning of Headless Planarian Flatworms

BioRxiv : the Preprint Server for Biology
J. BischofMichael Levin
January 12, 2021
Preprint
Open Access

Quantitative analysis of signaling responses during mouse primordial germ cell specification

BioRxiv : the Preprint Server for Biology
S. M. Morgani, Anna-Katerina Hadjantonakis
December 22, 2020
Preprint
Open Access

CGRP-receptor family reveals endogenous GPCR agonist bias and its significance in primary human cardiovascular cells

BioRxiv : the Preprint Server for Biology
A. ClarkGraham Ladds
January 7, 2021
Preprint
Open Access

Gpr161 ciliary pools prevent hedgehog pathway hyperactivation phenotypes specifically from lack of Gli transcriptional repression

BioRxiv : the Preprint Server for Biology
S.-h. HwangSaikat Mukhopadhyay
January 15, 2021
Preprint
Open Access

Characterisation of the R2R3 Myb subgroup 9 family of transcription factors in tomato

BioRxiv : the Preprint Server for Biology
G. V. Davis, Beverley Glover
December 22, 2020
Preprint
Open Access

Oligomerization of the Human Adenosine A2A Receptor Is Driven by the Intrinsically Disordered C-Terminus

BioRxiv : the Preprint Server for Biology
K. D. NguyenSongi Han
January 6, 2021
Preprint
Open Access

An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants

BioRxiv : the Preprint Server for Biology
Kui K ChanErik Procko
January 5, 2021
Preprint
Open Access

Single molecule analysis reveals positive allosteric modulators are required to stabilize the active state of a metabotropic glutamate receptor

BioRxiv : the Preprint Server for Biology
A.-M. CaoEmmanuel Margeat
December 30, 2020
Preprint
Open Access

Bab2 activates JNK signaling to reprogram Drosophila wing disc development

BioRxiv : the Preprint Server for Biology
Y. ZhaoY. Engström
January 7, 2021
Preprint
Open Access

NONCANONICAL ELECTROMECHANICAL COUPLING MECHANISM OF AN HCN CHANNEL

BioRxiv : the Preprint Server for Biology
G. DaiWilliam N. Zagotta
December 22, 2020
Preprint
Open Access

GPCR-mediated Activation of PLCg2 Initiates Dysregulated Recruitment of Neutrophils in Cold-induced Urticaria in PLAID Patients

BioRxiv : the Preprint Server for Biology
xut. jin
December 19, 2020
Preprint
Open Access

Differential Regulation of ERK and mTOR Signaling Pathways in Failing Human Hearts

MedRxiv : the Preprint Server for Health Sciences
R. K. AutenriedE Dale Abel
December 23, 2020
Preprint
Open Access

Identification of COVID-19-relevant transcriptional regulatory networks and associated kinases as potential therapeutic targets

BioRxiv : the Preprint Server for Biology
C. SuAmin Emad
January 7, 2021
Preprint
Open Access

Effects of Emodin, a Plant-Derived Anthraquinone, on TGFβ1-Induced Cardiac Fibroblast Activation and Function

BioRxiv : the Preprint Server for Biology
Mohamad AzharM. Chakrabarti
January 6, 2021
Preprint
Open Access

Binding and activation of serotonergic G-protein coupled receptors by the multimodal antidepressant vortioxetine.

BioRxiv : the Preprint Server for Biology
L. K. LadefogedBirgit Schioett
January 7, 2021
Preprint
Open Access

Overexpression of a G-protein coupled receptor-like gene affects encystment of Acanthamoeba castellanii

BioRxiv : the Preprint Server for Biology
S. RollandAscel Samba-Louaka
December 27, 2020
Preprint
Open Access

Artificial Antigen Presenting Cells for Detection and Desensitisation of Auto-reactive T cells Associated with Type 1 Diabetes

BioRxiv : the Preprint Server for Biology
Arbel Artzy-SchnirmanM. M. Stevens
December 30, 2020
Preprint
Open Access

Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG

BioRxiv : the Preprint Server for Biology
D. CarvalhoHubank

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