G-Protein-Coupled Receptors

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here is the latest research.

December 7, 2021
Open Access

AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma

BioRxiv : the Preprint Server for Biology
N. Comandante-LouMohammad Fallahi-Sichani
December 7, 2021
Open Access

Processing body dynamics drive non-genetic MEK inhibitors tolerance by fine-tuning KRAS and NRAS translation

BioRxiv : the Preprint Server for Biology
O. Vidal-CruchezPatrick Brest
December 7, 2021
Open Access

Tissue remodeling and cell signaling underpin changes in tumor microenvironment heterogeneity in glioma oncogenesis

BioRxiv : the Preprint Server for Biology
M. DinevskaTheo Mantamadiotis
December 7, 2021

Reduced MHC class II expression in medullary thyroid cancer identifies patients with poor prognosis.

Endocrine-related Cancer
Xianhui RuanXiangqian Zheng
December 7, 2021


Journal of Cellular Physiology
December 7, 2021

RPL35 promotes neuroblastoma progression via the enhanced aerobic glycolysis.

American Journal of Cancer Research
Weidong WuYong Zhu
December 7, 2021

Highly potent dopamine receptor D2 antagonist ONC206 demonstrates anti-tumorigenic activity in endometrial cancer.

American Journal of Cancer Research
Allison StaleyVictoria L Bae-Jump
December 7, 2021

aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis.

Proceedings of the National Academy of Sciences of the United States of America
Olivia Molinar-InglisJoAnn Trejo
December 7, 2021
Open Access

A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro.

Molecular Brain
Chihiro NakamotoTomonori Takeuchi
December 7, 2021

Th17 cell differentiation induced by cytopathogenic biotype BVDV-2 in bovine PBLCs.

BMC Genomics
Yanping LiXuenong Luo
December 7, 2021

Therapeutic Targets Underlying the Evolution of Potential Anti-Diabetic Agents: A Comprehensive Review.

Current Diabetes Reviews
Siddhita TiwariShubham Kumar

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