Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

September 14, 2021

Navigating genomic landscape of human adipose stem cell derived β-cells.

Stem Cells and Development
Srinivas V KoduruDino J Ravnic
September 14, 2021
Review
Open Access

C-peptide and residual β-cell function in pediatric diabetes - state of the art.

Pediatric endocrinology, diabetes, and metabolism
Milena Jamiołkowska-SztabkowskaArtur Bossowski
September 10, 2021

A therapeutic convection-enhanced macroencapsulation device for enhancing β cell viability and insulin secretion.

Proceedings of the National Academy of Sciences of the United States of America
Kisuk YangJeffrey M Karp
September 10, 2021
Review
Open Access

The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror.

International Journal of Molecular Sciences
María Sofía MartínezLisse Angarita
September 10, 2021

The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production.

Developmental Cell
Lina SakhnenyLimor Landsman
September 7, 2021

A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.

Molecular Metabolism
Nirav Florian ChhabraMartin Hrabě de Angelis
September 6, 2021

A bioinformatics analysis of the contribution of m6A methylation to the occurrence of diabetes mellitus.

Endocrine Connections
Lei LeiJia-Ping Wang
September 6, 2021
Review
Open Access

How Perturbated Metabolites in Diabetes Mellitus Affect the Pathogenesis of Hypertension?

Frontiers in Physiology
Zhangchi NingAiping Lu
August 31, 2021

A20 controls expression of beta cell regulatory genes and transcription factors.

Journal of Molecular Endocrinology
Wiktoria RatajczakCatriona Kelly
August 31, 2021

OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1.

Diabetes
Ramkumar MohanEmilyn U Alejandro
August 28, 2021
Review

Chitosan for biomedical applications, promising antidiabetic drug delivery system, and new diabetes mellitus treatment based on stem cell.

International Journal of Biological Macromolecules
Sarah I OthmanRehab Abdelmonem
August 27, 2021

Progressive endoplasmic reticulum stress over time due to human insulin gene mutation contributes to pancreatic beta cell dysfunction.

Diabetologia
Nur Shabrina AmirruddinAdrian Kee Keong Teo
August 26, 2021
Preprint
Open Access

A missense KCNQ1 Mutation Impairs Insulin Secretion in Neonatal Diabetes

BioRxiv : the Preprint Server for Biology
Z. ZhouZ. Izsvak
August 25, 2021

From insulin injections to islet transplantation: an overview of the journey.

Diabetes, Obesity & Metabolism
Paget MichelleDowning Richard
August 24, 2021

Recent Advances in the Generation of β-Cells from Induced Pluripotent Stem Cells as a Potential Cure for Diabetes Mellitus.

Advances in Experimental Medicine and Biology
Akriti AgrawalRajkumar P Thummer

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