Genetics of Killer-cell Immunoglobulin-like Receptors

Killer-cell immunoglobulin-like receptors (KIRs) are expressed on NK cells and a subset of T cells and mediate inhibition or activation of cytotoxic activity. KIRs are highly polymorphic and the ability to sequence and phenotype these variations may lead to a better understanding of various infectious and autoimmune pathologies. Find the latest research on KIRs here.

September 29, 2020
Open Access

Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations

Frontiers in Immunology
Luciana de Brito VargasDanillo G Augusto
July 14, 2020
Open Access

Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+ NKG2A- NK cells

ELife
Sabrina Bianca BennsteinMarkus Uhrberg
August 15, 2020

Natural killer cell impairment in ovarian clear cell carcinoma

Journal of Leukocyte Biology
Ornella PatriziGiovanna Tabellini
October 21, 2020
Open Access

KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling

Cancers
Lourdes GimenoAlfredo Minguela
September 16, 2020
Preprint
Open Access

Characterization of Circulating Mucosal Associated Invariant T cells in Colorectal Cancer Patients

ResearchSquare
Mohamed M Abu HassanHuda A Ahmed
August 12, 2020
Preprint
Open Access

Efficacy of Targeting SARS-CoV-2 by CAR-NK Cells

BioRxiv : the Preprint Server for Biology
M. T. MaDongfang Liu
July 15, 2020

Inhibitory KIR2DL2 Gene: Risk for Deep Endometriosis in Euro-descendants

Reproductive Sciences
Maria Lucia Carnevale MarinJorge Kalil
October 6, 2020
Open Access

Analysis of Killer Cell Immunoglobulin-Like Receptor Genes and Their HLA Ligands in Inflammatory Bowel Diseases

Journal of Immunology Research
Fereshteh BeigmohammadiNima Rezaei
July 17, 2020
Preprint
Open Access

Characterization of Circulating Mucosal Associated Invariant T cells in Colorectal Cancer Patients

ResearchSquare
Mohamed M Abu HassanHuda A Ahmed
September 16, 2020

CD56dim CD57- NKG2C+ NK cells retaining proliferative potential are possible precursors of CD57+ NKG2C+ memory-like NK cells

Journal of Leukocyte Biology
Polina A KobyzevaElena I Kovalenko
July 30, 2020
Preprint
Open Access

Genetically Determined Strength of Natural Killer Cells is Enhanced by Adaptive HLA class I Admixture in East Asians

BioRxiv : the Preprint Server for Biology
Z. DengPaul J Norman
September 29, 2020
Review
Open Access

Influence of KIR and NK Cell Reconstitution in the Outcomes of Hematopoietic Stem Cell Transplantation

Frontiers in Immunology
Fei GaoYanmin Zhao
August 18, 2020
Review
Open Access

NK cells and ILCs in tumor immunotherapy

Molecular Aspects of Medicine
Simona SivoriLorenzo Moretta
August 28, 2020
Open Access

The Enigma of Low COVID-19 Fatality Rate in India

Frontiers in Genetics
Arghadip SamaddarSanjeev Misra
October 6, 2020
Review
Open Access

The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates

Frontiers in Immunology
Jesse BruijnesteijnRonald E Bontrop

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