Genetics of Pain

Subtle changes in DNA could partly explain the variation in individual differences in pain. There is growing evidence that a number of genes play a critical role in determining pain sensitivity, pain reporting and susceptibility to developing chronic pain and their response to surgical outcomes primarily, pain.

February 23, 2021
Open Access

Cellular, physiological, and behavioral validation of a CRFR1:Cre-tdTomato transgenic rat for use in basic neuroscience research

BioRxiv : the Preprint Server for Biology
Marcus M WeeraN. W. Gilpin
February 24, 2021

Mechanobiology and Adaptive Plasticity (MAP) Theory as a Potential Confounding Factor in Predicting Musculoskeletal Foot Function.

Journal of the American Podiatric Medical Association
Greg Quinn
February 22, 2021
Open Access

The non-benzodiazepine anxiolytic etifoxine limits the sensory-affective expression of pain following streptozotocin-induced diabetic neuropathy

BioRxiv : the Preprint Server for Biology
G. GazzoPierrick Poisbeau
February 22, 2021
Open Access

The aversive value of pain in human decision-making

BioRxiv : the Preprint Server for Biology
H. SlimaniMathieu Roy
February 21, 2021

Mendelian randomization highlights insomnia as a risk factor for pain diagnoses.

Martin BrobergFinnGen
February 19, 2021

Mas-related G protein-coupled receptors (Mrgprs) - Key regulators of neuroimmune interactions.

Neuroscience Letters
Nadine SerhanNicolas Gaudenzio
February 19, 2021

Enhancement of morphine-induced antinociception after electroconvulsive shock in mice.

Molecular Pain
Ken IwataKazutaka Ikeda
February 18, 2021

Treatment of chronic musculoskeletal pain with electron modulation procedure.

Pain Management
William J NahmGerardo Hizon
February 14, 2021

The morphological and microscopical characteristics of posterior layer of human thoracolumbar fascia; A potential source of low back pain.

Morphologie : Bulletin De L'Association Des Anatomistes
S MarpalliB M George
February 13, 2021
Open Access

Abnormal neurometabolites in fibromyalgia patients: Magnetic resonance spectroscopy study.

Molecular Pain
Ye-Ha JungDo-Hyung Kang
February 12, 2021
Open Access

Lack of effect of different pain-related manipulations on opioid self-administration, reinstatement of opioid seeking, and opioid choice in rats

BioRxiv : the Preprint Server for Biology
David J ReinerS. S. Negus
February 12, 2021
Open Access

The emerging role of kainate receptor functional dysregulation in pain.

Molecular Pain
Huili LiYun Wang
February 12, 2021
Open Access

Pain Control by Targeting Oxidized Phospholipids: Functions, Mechanisms, Perspectives.

Frontiers in Endocrinology
Beatrice OehlerHeike L Rittner

Sign up to follow this feed and discover related papers.

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS: Genetics

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Alzheimer's Disease: Genetics

Alzheimer's disease is a neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations with this feed.

Antisense Oligonucleotide Therapies: ND

Antisense oligonucleotides are synthetic DNA oligomers that hybridize to a target RNA. This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases.

Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Breast Cancer: Risk Factors

Breast cancer is a multifactorial disease that is influenced by both environmental and genetic factors. Discover the latest research on the environmental and genetic risk factors for breast cancer here.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Cell-Type-Specific Viral Vectors

Viral vectors are used in biological research and therapy to deliver genetic material into cells. However, the efficiency of viral vectors varies depending on the cell type. Here is the latest research on cell-type-specific viral vectors.

© 2021 Meta ULC. All rights reserved