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Genetics of Pain

Genetics of Pain diagram by Sepideh Sadaghiani et al
Sepideh Sadaghiani et al

Subtle changes in DNA could partly explain the variation in individual differences in pain. There is growing evidence that a number of genes play a critical role in determining pain sensitivity, pain reporting and susceptibility to developing chronic pain and their response to surgical outcomes primarily, pain.

Top 20 most recent papers
bioRxiv

Transcriptional reprogramming of distinct peripheral sensory neuron subtypes after axonal injury

bioRxivNovember 16, 2019
William RenthalClifford J Woolf
36
Molecular Psychiatry

The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure

Molecular PsychiatryNovember 19, 2019
Samuel A. McLeanRonald C. Kessler
67
1
bioRxiv

Perinatal selective serotonin reuptake inhibitor exposure and behavioral outcomes: a systematic review and meta-analyses of animal studies

bioRxivDecember 6, 2019
Anouschka S. RamsteijnJocelien D.A. Olivier
2
Science Translational Medicine

Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models

Science Translational MedicineNovember 20, 2019
Ping LiaoHuai-Yu Yang
7
bioRxiv

Evolutionarily ancient BAH-PHD protein mediates Polycomb silencing

bioRxivDecember 6, 2019
Elizabeth T WilesEric U Selker
6
bioRxiv

Cell-type specificity of neuronal excitability and morphology in the central amygdala

bioRxivNovember 18, 2019
Anisha P. AdkeYarimar Carrasquillo
24
bioRxiv

Antibody responses to immunization require sensory neurons

bioRxivNovember 30, 2019
Aisling TynanKevin J. Tracey
23
bioRxiv

Novel Analgesic Agents Obtained by Molecular Hybridization of Orthosteric and Allosteric Ligands

bioRxivDecember 5, 2019
Carlo MateraSimona Bertoni
1
Circulation Research

Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes

Circulation ResearchNovember 19, 2019
Zhi-Fen ChenChad A Cowan
1
bioRxiv

Effect Of Inflammatory Pain On Alcohol-Induced Dopamine Release In The Nucleus Accumbens: Behavioural Implications In Rat Models.

bioRxivDecember 2, 2019
Yolanda Campos-JuradoLucía Hipólito
8
bioRxiv

Junctophilin-4 is essential for signalling at plasma membrane-endoplasmic reticulum junctions in sensory neurons

bioRxivNovember 15, 2019
Alexandra HogeaNikita L Gamper
4
bioRxiv

Genome-wide association and functional analyses identify CASC20 and KIF26B as target loci in heterotopic ossification

bioRxivNovember 21, 2019
Konstantinos HatzikotoulasJeremy Mark Wilkinson
7
Scientific Reports

Population genomics of two congeneric Palaearctic shorebirds reveals differential impacts of Quaternary climate oscillations across habitats types

Scientific ReportsDecember 3, 2019
Hui Xian TanF Gözde Çilingir
bioRxiv

Clinically significant acute pain disturbs motor cortex intracortical inhibition and facilitation in orthopedic trauma patients: A TMS study

bioRxivNovember 28, 2019
Marianne JodoinLouis De Beaumont
3
bioRxiv

Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

bioRxivDecember 5, 2019
Dara BreeDan M Levy
2
bioRxiv

Evaluation of the impact of Shigella virulence genes on the basis of clinical features observed in patients with shigellosis

bioRxivDecember 6, 2019
Visnu Pritom ChowdhuryKaisar Ali Talukder
1
Brain : a Journal of Neurology

A causal role for TRESK loss of function in migraine mechanisms

Brain : a Journal of NeurologyNovember 20, 2019
Philippa PettingillMuhammed Z Cader
19
bioRxiv

Predictive Coding Models for Pain Perception

bioRxivNovember 18, 2019
Yuru SongZhe Sage Chen
3
Methods in Molecular Biology

Gene Fusion Discovery with INTEGRATE

Methods in Molecular BiologyNovember 16, 2019
Jin Mai Zhang, Christopher A Maher
2
Cell

Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

CellNovember 19, 2019
Alfredo M ValenciaCigall Kadoch
144
1
3

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