Feed Preview

Fast Growing

Genetics of Pain

Genetics of Pain diagram by Sepideh Sadaghiani et al
Sepideh Sadaghiani et al

Subtle changes in DNA could partly explain the variation in individual differences in pain. There is growing evidence that a number of genes play a critical role in determining pain sensitivity, pain reporting and susceptibility to developing chronic pain and their response to surgical outcomes primarily, pain.

Top 20 most recent papers

Transcriptional reprogramming of distinct peripheral sensory neuron subtypes after axonal injury

bioRxivNovember 16, 2019
William RenthalClifford J Woolf
Molecular Psychiatry

The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure

Molecular PsychiatryNovember 19, 2019
Samuel A. McLeanRonald C. Kessler

Perinatal selective serotonin reuptake inhibitor exposure and behavioral outcomes: a systematic review and meta-analyses of animal studies

bioRxivDecember 6, 2019
Anouschka S. RamsteijnJocelien D.A. Olivier
Science Translational Medicine

Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models

Science Translational MedicineNovember 20, 2019
Ping LiaoHuai-Yu Yang

Evolutionarily ancient BAH-PHD protein mediates Polycomb silencing

bioRxivDecember 6, 2019
Elizabeth T WilesEric U Selker

Cell-type specificity of neuronal excitability and morphology in the central amygdala

bioRxivNovember 18, 2019
Anisha P. AdkeYarimar Carrasquillo

Antibody responses to immunization require sensory neurons

bioRxivNovember 30, 2019
Aisling TynanKevin J. Tracey

Novel Analgesic Agents Obtained by Molecular Hybridization of Orthosteric and Allosteric Ligands

bioRxivDecember 5, 2019
Carlo MateraSimona Bertoni
Circulation Research

Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes

Circulation ResearchNovember 19, 2019
Zhi-Fen ChenChad A Cowan

Effect Of Inflammatory Pain On Alcohol-Induced Dopamine Release In The Nucleus Accumbens: Behavioural Implications In Rat Models.

bioRxivDecember 2, 2019
Yolanda Campos-JuradoLucía Hipólito

Junctophilin-4 is essential for signalling at plasma membrane-endoplasmic reticulum junctions in sensory neurons

bioRxivNovember 15, 2019
Alexandra HogeaNikita L Gamper

Genome-wide association and functional analyses identify CASC20 and KIF26B as target loci in heterotopic ossification

bioRxivNovember 21, 2019
Konstantinos HatzikotoulasJeremy Mark Wilkinson
Scientific Reports

Population genomics of two congeneric Palaearctic shorebirds reveals differential impacts of Quaternary climate oscillations across habitats types

Scientific ReportsDecember 3, 2019
Hui Xian TanF Gözde Çilingir

Clinically significant acute pain disturbs motor cortex intracortical inhibition and facilitation in orthopedic trauma patients: A TMS study

bioRxivNovember 28, 2019
Marianne JodoinLouis De Beaumont

Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

bioRxivDecember 5, 2019
Dara BreeDan M Levy

Evaluation of the impact of Shigella virulence genes on the basis of clinical features observed in patients with shigellosis

bioRxivDecember 6, 2019
Visnu Pritom ChowdhuryKaisar Ali Talukder
Brain : a Journal of Neurology

A causal role for TRESK loss of function in migraine mechanisms

Brain : a Journal of NeurologyNovember 20, 2019
Philippa PettingillMuhammed Z Cader

Predictive Coding Models for Pain Perception

bioRxivNovember 18, 2019
Yuru SongZhe Sage Chen
Methods in Molecular Biology

Gene Fusion Discovery with INTEGRATE

Methods in Molecular BiologyNovember 16, 2019
Jin Mai Zhang, Christopher A Maher

Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

CellNovember 19, 2019
Alfredo M ValenciaCigall Kadoch

See more papers from this feed

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Alzheimer's Disease: Genetics

Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Breast Cancer: Risk Factors

Breast cancer is a multifactorial disease that is influenced by both environmental and genetic factors. Discover the latest research on the environmental and genetic risk factors for breast cancer here.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Cell-Type-Specific Viral Vectors

Viral vectors are used in biological research and therapy to deliver genetic material into cells. However, the efficiency of viral vectors varies depending on the cell type. Here is the latest research on cell-type-specific viral vectors.

Childhood Vascular Tumor: Genetics

Childhood vascular tumors are formed from cells related to blood vessels or lymph vessels. Here is the latest research on the genetics of childhood vascular tumors.

© 2019 Meta ULC. All rights reserved