Genome Editing in Cardiovascular Diseases

Genome editing is a powerful tool to study specific mutations or genes involved in the development and progression of cardiovascular disease. Discover the latest research on Genome Editing in Cardiovascular Disease here.

April 18, 2021

CRISPR/Cas9-mediated knockout of PIM3 suppresses tumorigenesis and cancer cell stemness in human hepatoblastoma cells.

Cancer Gene Therapy
Raoud MarayatiElizabeth A Beierle
April 17, 2021

Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell development.

Immunity
Luyi TianShalin H Naik
April 16, 2021

How orthodontic research can be enriched and advanced by the novel and promising evolutions in biomedicine.

Journal of Orthodontics
Mohamed G HassanAthanasios E Athanasiou
April 16, 2021
Open Access

A stress-free strategy to correct point mutations in patient iPS cells.

Stem Cell Research
Jingli CaiLorraine Iacovitti
April 16, 2021
Review

Genetic therapies for the first molecular disease.

The Journal of Clinical Investigation
Phillip A DoerflerMitchell J Weiss
April 16, 2021
Open Access

CRISPR/Cas9 ribonucleoprotein-mediated knockin generation in hTERT-RPE1 cells.

STAR Protocols
Sabrina GhettiLuca L Fava
April 15, 2021
Review

Current applications of SCNT in advanced breeding and genome editing in livestock.

Reproduction : the Official Journal of the Society for the Study of Fertility
Cesare Galli, Giovanna Lazzari
April 14, 2021
Open Access

Constitutive depletion of Slc34a2/NaPi-IIb in rats causes perinatal mortality.

Scientific Reports
Eva Maria Pastor-ArroyoCarsten A Wagner
April 14, 2021

Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition.

Nature Genetics
Daichi InoueOmar Abdel-Wahab
April 14, 2021
Open Access

Base editing repairs an SGCA mutation in human primary muscle stem cells.

JCI Insight
Helena EscobarSimone Spuler
April 13, 2021
Preprint
Open Access

Comprehensive analysis of prime editing outcomes in human embryonic stem cells

BioRxiv : the Preprint Server for Biology
O. HabibSangsu Bae
April 12, 2021
Preprint
Open Access

Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy

BioRxiv : the Preprint Server for Biology
N.-V. MohamedThomas M. Durcan
April 12, 2021
Review
Open Access

Hermansky-Pudlak Syndrome and Lung Disease: Pathogenesis and Therapeutics.

Frontiers in Pharmacology
Pamela Velázquez-DíazYang Zhou
April 11, 2021

Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.

Cell
James K NuñezJonathan S Weissman
April 10, 2021
Open Access

Generation of Murine Bone Marrow and Fetal Liver Chimeras.

Current Protocols
Stéphane ChappazBenjamin T Kile
April 8, 2021
Open Access

Zbp1-positive cells are osteogenic progenitors in periodontal ligament.

Scientific Reports
Tsugumi UedaShinya Murakami
April 10, 2021

The Genetic Basis of Reporter Mouse Strains.

Advances in Experimental Medicine and Biology
Gyeong-Nam Kim, Young Hoon Sung

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